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Extract from the Register of European Patents

EP About this file: EP3999072

EP3999072 - BORON-CONTAINING RHO KINASE INHIBITORS [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  16.02.2024
Database last updated on 09.07.2024
FormerRequest for examination was made
Status updated on  22.04.2022
FormerThe international publication has been made
Status updated on  22.01.2021
Most recent event   Tooltip17.06.2024New entry: Reply to examination report 
Applicant(s)For all designated states
Percipiad, Inc.
46 Steamwhistle Drive
Warminster PA 18974 / US
[2022/21]
Inventor(s)01 / HORMANN, Robert, Eugene
413 Richards Road
Melrose Park, PA 19027 / US
02 / PADIDAM, Malla
228 Cassandra Drive
Chalfont, PA 18914 / US
 [2022/21]
Representative(s)Studio Torta S.p.A., et al
Via Viotti, 9
10121 Torino / IT
[N/P]
Former [2022/21]Casciano, Lidia Giulia Rita, et al
Studio Torta S.p.A.
Via Viotti, 9
10121 Torino / IT
Application number, filing date20841243.717.07.2020
[2022/21]
WO2020US42538
Priority number, dateUS201962875270P17.07.2019         Original published format: US 201962875270 P
[2022/21]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021011873
Date:21.01.2021
Language:EN
[2021/03]
Type: A1 Application with search report 
No.:EP3999072
Date:25.05.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 21.01.2021 takes the place of the publication of the European patent application.
[2022/21]
Search report(s)International search report - published on:US21.01.2021
(Supplementary) European search report - dispatched on:EP07.06.2023
ClassificationIPC:C07F5/02, A61P27/06, A61P25/28
[2023/27]
CPC:
C07F5/025 (EP,US); A61K45/06 (US); A61P25/28 (EP);
A61P27/06 (EP); C07F5/02 (EP)
Former IPC [2022/21]A61K31/69, C07F5/02, A61P21/00, A61P25/28, A61P35/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/21]
TitleGerman:BORHALTIGE RHO-KINASE-INHIBITOREN[2022/21]
English:BORON-CONTAINING RHO KINASE INHIBITORS[2022/21]
French:INHIBITEURS DE LA RHO KINASE CONTENANT DU BORE[2022/21]
Entry into regional phase12.01.2022National basic fee paid 
12.01.2022Search fee paid 
12.01.2022Designation fee(s) paid 
12.01.2022Examination fee paid 
Examination procedure12.01.2022Examination requested  [2022/21]
27.12.2023Amendment by applicant (claims and/or description)
27.12.2023Date on which the examining division has become responsible
15.02.2024Despatch of a communication from the examining division (Time limit: M04)
14.06.2024Reply to a communication from the examining division
Fees paidRenewal fee
18.07.2022Renewal fee patent year 03
24.07.2023Renewal fee patent year 04
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]  - DAYAL NEETU ET AL, "Potently inhibiting cancer cell migration with novel 3H-pyrazolo[4,3-f]quinoline boronic acid ROCK inhibitors", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 180, doi:10.1016/J.EJMECH.2019.06.089, ISSN 0223-5234, (20190629), pages 449 - 456, (20190629), XP085819385 [A] 1-15 * figures 1-4 * * abstract *

DOI:   http://dx.doi.org/10.1016/j.ejmech.2019.06.089
International search[A]US2010280011  (DELONG MITCHELL A [US], et al) [A] 1, 15, 20/(1,15) * para [0165], [0167], [0191], Table 3 *;
 [A]US2017137443  (WANG GUANGDI [US], et al) [A] 1, 15, 20/(1,15) * para [0017], [0021], Fig 9; Fig 10 *;
 [A]  - JIANG et al., "Boron-Based 4-Hydroxytamoxifen Bioisosteres for Treatment of de Novo Tamoxifen Resistant Breast Cancer", ACS Med. Chem. Lett., (20120000), vol. 3, doi:doi.org/10.1021/ml3000287., pages 392 - 396, XP055195676 [A] 1, 15, 20/(1,15) * abstract; pg 393, Fig 1; pg 394, coi 1, para 2 to pg 395, col 1, para 1 *

DOI:   http://dx.doi.org/10.1021/ml3000287
 [A]  - Oliveira Ramon Guerra De, Guerra Fabiana Sélos, Mermelstein Cláudia Dos Santos, Fernandes Patrícia Dias, Bastos Isadora Tairinne De Sena, Costa Fanny Nascimento, Barroso Regina Cely Rodrigues, Ferreira Fabio Furlan, Fraga Carlos Alberto Manssour, "Synthesis and pharmacological evaluation of novel isoquinoline N-sulphonylhydrazones designed as ROCK inhibitors", JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, (20181200), vol. 33, no. 1, doi:https://doi.org/10.1080/14756366.2018.1490732., pages 1181 - 1193, XP055785427 [A] 1, 15, 20/(1,15) * pg 1182, col 1, para 2 to col 2, para 1; Fig 1; pg 1184, col 1, para 1 *

DOI:   http://dx.doi.org/10.1080/14756366.2018.1490732
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.