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Extract from the Register of European Patents

EP About this file: EP4015516

EP4015516 - BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  20.05.2022
Database last updated on 24.08.2024
FormerThe international publication has been made
Status updated on  22.01.2021
Most recent event   Tooltip24.07.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Korea Research Institute of Bioscience and Biotechnology
125, Gwahak-ro, Yuseong-gu
Daejeon 34141 / KR
[2022/25]
Inventor(s)01 / KIM, Bo Yeon
125, Gwahak-ro, Yuseong-gu
Daejeon 34141 / KR
02 / SOUNG, Nak Kyun
125, Gwahak-ro, Yuseong-gu
Daejeon 34141 / KR
03 / AHN, Mija
125, Gwahak-ro, Yuseong-gu
Daejeon 34141 / KR
04 / HAN, Ho Jin
125, Gwahak-ro, Yuseong-gu
Daejeon 34141 / KR
05 / RYOO, In Ja
125, Gwahak-ro, Yuseong-gu
Daejeon 34141 / KR
06 / HWANG, Joonsung
125, Gwahak-ro, Yuseong-gu
Daejeon 34141 / KR
 [2022/25]
Representative(s)Altmann Stößel Dick Patentanwälte PartG mbB
Theodor-Heuss-Anlage 2
68165 Mannheim / DE
[2022/25]
Application number, filing date20841558.814.07.2020
[2022/25]
WO2020KR09262
Priority number, dateKR2019008504515.07.2019         Original published format: KR 20190085045
[2022/25]
Filing languageKO
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021010731
Date:21.01.2021
Language:KO
[2021/03]
Type: A1 Application with search report 
No.:EP4015516
Date:22.06.2022
Language:EN
[2022/25]
Search report(s)International search report - published on:KR21.01.2021
(Supplementary) European search report - dispatched on:EP26.07.2023
ClassificationIPC:C07D405/12, A61K31/404, A61P35/00
[2022/25]
CPC:
A61P35/00 (EP,KR); C07D405/12 (EP,CN,KR,US); A61K31/404 (KR);
A61P35/04 (US); C07D209/30 (CN); C07D307/85 (CN)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/25]
TitleGerman:AUF BENZOFURAN BASIERENDES N-ACYLHYDRAZONDERIVAT UND DIESES ENTHALTENDE PHARMAZEUTISCHE ZUSAMMENSETZUNG[2022/25]
English:BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME[2022/25]
French:DÉRIVÉ DE N-ACYLHYDRAZONE À BASE DE BENZOFURANE ET COMPOSITION PHARMACEUTIQUE LE COMPRENANT[2022/25]
Entry into regional phase10.02.2022Translation filed 
10.02.2022National basic fee paid 
10.02.2022Search fee paid 
10.02.2022Designation fee(s) paid 
10.02.2022Examination fee paid 
Examination procedure10.02.2022Examination requested  [2022/25]
31.01.2024Amendment by applicant (claims and/or description)
31.01.2024Date on which the examining division has become responsible
Fees paidRenewal fee
16.07.2022Renewal fee patent year 03
27.07.2023Renewal fee patent year 04
24.07.2024Renewal fee patent year 05
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]  - Pubchem, "5,7-dibromo-N-[(Z)-(2-methyl-1H-indol-3-yl)methylideneamino]-1-benzofuran-2-carboxamide", PubChem, (20190115), Database accession no. 135563355, URL: https%3A%2F%2Fpubchem.ncbi.nlm.nih.gov%2Fcompound%2F135563355, XP093064537 [X] 1-4 * abstract *
 [X]  - Cap, "2-Benzofurancarboxylic acid, 5-ethoxy-, 2-[(1,2-dimethyl-1H-indol-3-yl)methylene]hydrazide", REGISTRY, (20180430), Database accession no. 2221847-46-5, XP093064559 [X] 1-4 * abstract *
 [X]  - Cap, "2-Benzofurancarboxylic acid, 5-bromo-7-iodo-, 2-[(2-methyl-1H-indol-3-yl)methylene]hydrazide", REGISTRY, (20180429), Database accession no. 2221523-47-1, XP093064564 [X] 1-4 * abstract *
 [X]  - Cap, "2-Benzofurancarboxylic acid, 5-ethoxy-, 2-[(2-methyl-1H-indol-3-yl)methylene]hydrazide", REGISTRY, (20180425), Database accession no. 2218954-87-9, XP093064571 [X] 1-4 * abstract *
 [X]  - Cap, "2-Benzofurancarboxylic acid, 5-bromo-, 2-[(1,2-dimethyl-1H-indol-3-yl)methylene]hydrazide", REGISTRY, (20060605), Database accession no. 890561-50-9, XP093064572 [X] 1-4 * abstract *
 [X]  - Chemcats, "2-Benzofurancarboxylic acid, 5-bromo-, 2-[[2-(1-methylpropyl)-1H-indol-3-yl]methylene]hydrazide", REGISTRY, (20060124), Database accession no. 872528-89-7, XP093064579 [X] 1,2,4 * abstract *
 [X]  - "2-Benzofurancarboxylic acid, 5-chloro-, 2-[(1,2-dimethyl-1H-indol-3-yl)methylene]hydrazide", REGISTRY, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (20020822), Database accession no. RN 444671-24-3, URL: STN, XP055889691 [X] 1-6 * abstract *
 [X]  - Chemical Library, "2-Benzofurancarboxylic acid, 5-chloro-, 2-[(2-methyl-1H-indol-3-yl)methylene]hydrazide", REGISTRY, (20020820), Database accession no. 444292-03-9, XP093064588 [X] 1-6 * abstract *
 [A]  - DAS MUKHERJEE DIPANWITA ET AL, "Development of Novel Bis(indolyl)-hydrazide-Hydrazone Derivatives as Potent Microtubule-Targeting Cytotoxic Agents against A549 Lung Cancer Cells", BIOCHEMISTRY, (20160519), vol. 55, no. 21, doi:10.1021/acs.biochem.5b01127, ISSN 0006-2960, pages 3020 - 3035, XP093064611 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1021/acs.biochem.5b01127
International search[X]US2002128292  (CAI SUI XIONG [US], et al) [X] 1-17 * See claims 11, 13 and 28; and paragraphs [0136], [0148] and [0149]. *;
 [A]WO2013032907  (BROAD INST INC [US], et al) [A] 1-17 * See claims 1, 4, 8(compound 41) and 14. *;
 [A]US2014357682  (LLOYD DAVID GEORGE [IE], et al) [A] 1-17 * See entire document. *;
 [A]KR101790193B  [A] 1-17* See entire document. *
 [AX]  - Chemical Abstract Compound. STN express. RN: 2220348-97-8 (27 April 2018). See the compounds. [A] 7-17 * See the compounds. * [X] 1-6
 [X]  - Chemical Abstract Compound. STN express. RN: 444671-24-3 (22 August 2002). See the compounds. [X] 1-6 * See the compounds. *
 [X]  - Chemical Abstract Compound. STN express. RN: 444292-03-9 (20 August 2002). See the compounds. [X] 1-6 * See the compounds. *
by applicantKR20140128238
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