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Extract from the Register of European Patents

EP About this file: EP4085055

EP4085055 - AMINOPYRIMIDINE COMPOUNDS [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  07.10.2022
Database last updated on 14.11.2024
FormerThe international publication has been made
Status updated on  10.07.2021
Formerunknown
Status updated on  03.02.2021
Most recent event   Tooltip27.12.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
Tyra Biosciences, Inc.
2333 State Street Suite 201
Carlsbad, CA 92008 / US
[2022/45]
Inventor(s)01 / HUDKINS, Robert, L.
2333 State Street, Suite 201
Carlsbad, CA 92008 / US
02 / BENSEN, Daniel, C.
2333 State Street, Suite 201
Carlsbad, CA 92008 / US
 [2022/45]
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2022/45]
Application number, filing date20845540.230.12.2020
[2022/45]
WO2020US67417
Priority number, dateUS201962954899P30.12.2019         Original published format: US 201962954899 P
US202062968461P31.01.2020         Original published format: US 202062968461 P
[2022/45]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021138392
Date:08.07.2021
Language:EN
[2021/27]
Type: A1 Application with search report 
No.:EP4085055
Date:09.11.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 08.07.2021 takes the place of the publication of the European patent application.
[2022/45]
Search report(s)International search report - published on:EP08.07.2021
ClassificationIPC:C07D403/04, C07D417/12, A61K31/541, A61P35/00
[2022/45]
CPC:
C07D403/04 (EP,US); A61P35/00 (US); C07D401/14 (US);
C07D417/12 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/45]
TitleGerman:AMINOPYRIMIDIN-VERBINDUNGEN[2022/45]
English:AMINOPYRIMIDINE COMPOUNDS[2022/45]
French:COMPOSÉS D'AMINOPYRIMIDINE[2022/45]
Entry into regional phase01.08.2022National basic fee paid 
01.08.2022Designation fee(s) paid 
01.08.2022Examination fee paid 
Examination procedure01.08.2022Examination requested  [2022/45]
01.08.2022Date on which the examining division has become responsible
02.03.2023Amendment by applicant (claims and/or description)
Fees paidRenewal fee
01.08.2022Renewal fee patent year 03
27.12.2023Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[A]WO2007149427  (MERCK & CO INC [US], et al) [A] 1-65* page 54, compound I-17; page 66, example 8;; claim - *
by applicantJPH0586892
 US2011008347
 CN102741256
 US2013009621
 WO2014071419
 WO2015099127
 WO2015120094
 WO2015150900
 US2015366866
 US9254288
 US9267176
 WO2016030509
 EP2203449
 EP3023101
 WO2016084883
 AU2014362227
 WO2016105503
 US2016215350
 US2016235744
 WO2016139227
 US9447098
    - BEENKEN, A., Nat. Rev. Drug Discov., (20090000), vol. 8, pages 235 - 253
    - JOHNSON et al., Adv. Cancer Res., (19930000), vol. 60, pages 1 - 40
    - WILKIE et al., Curr. Biol., (19950000), vol. 5, pages 500 - 507
    - JOHNSON et al., Mol. Cell. Biol., (19950000), vol. 11, pages 4627 - 4634
    - CHELLAIAH et al., J. Biol. Chem., (19940000), vol. 269, pages 11620 - 11627
    - ZIMMER et al., J. Biol. Chem., (19930000), vol. 268, pages 7899 - 7903
    - CHEON et al., Proc. Natl. Acad. Sci. U.S.A., (19940000), vol. 91, pages 989 - 993
    - MIKI et al., Proc. Natl. Acad. Sci. U.S.A., (19920000), vol. 89, pages 246 - 250
    - BAROY et al., PloS One, (20160000), vol. 11, no. 9, page e0163859
    - REN et al., Int. J. Cancer, (20160000), vol. 139, no. 4, pages 836 - 40
    - MARCHWICKA et al., CellBiosci., (20160000), vol. 6, page 7
    - KASAIAN et al., BMC Cancer., (20150000), vol. 15, page 984
    - VAKIL et al., Neuro-Oncology, vol. 18, page iii93
    - ASTSATUROV et al., Journal of Clinical Oncology, vol. 34, page iii93
    - NGUYEN et al., Molecular Cancer Therapeutics, vol. 14, no. 12
    - REUTHER et al., Journal of Molecular Diagnostics, vol. 17, no. 6, page 813
    - MOEINI et al., Clin. Cancer. Res., (20160000), vol. 22, no. 2, pages 291 - 300
    - SCHROCK et al., J Thorac. Oneal., (20180000), no. 18, pages S1556 - 0864
    - PEKMEZCI et al., Acta Nurotaphol. Commun., vol. 6, no. 1, page 47
    - LOWERY et al., Clin Cancer Res, (20180000), page 0078
    - RYLAND et al., J Clin Pathol, (20180000), pages 2018 - 205195
    - FERGUSON et al., J Neuropatho/Exp Neural, (20180000), vol. 77, no. 6, pages 437 - 442
    - WU et al., BMC Cancer, (20180000), vol. 18, no. 1, page 343
    - SHIBATA et al., Cancer Sci, (20180000), vol. 109, no. 5, pages 1282 - 1291
    - CHAKRABARTY et al., Br J Cancer, (20170000), vol. 1117, no. 11, pages 1592 - 1599
    - HALL et al., PLoS One, (20160000), vol. 11, no. 9, page e1062594
    - JOHNSON et al., Oncologist, (20170000), vol. 22, no. 12, pages 1478 - 1490
    - YANG et al., Am J Hum Genet, (20160000), vol. 98, no. 5, pages 843 - 856
    - BABINATURNER, Nat Rev Cancer, (20170000), vol. 17, no. 5, pages 318 - 332
    - RYLAND et al., J Clin Pathol., (20180514), pages 2018 - 205195
    - KUMAR et al., Am JClin Pathol, (20150000), vol. 143, no. 5, pages 738 - 748
    - GRAND et al., Genes Chromosomes Cancer, (20040000), vol. 40, no. 1, pages 78 - 83
    - REESER et al., J Mol Diagn, (20170000), vol. 19, no. 5, pages 682 - 696
    - BASTURK et al., Mod Pathol, (20170000), vol. 30, no. 12, pages 1760 - 1772
    - WANG et al., Cancer, (20170000), vol. 123, no. 20, pages 3916 - 3924
    - SHIMADA et al., Oncotarget, (20170000), vol. 8, no. 55, pages 93567 - 93579
    - BUSSE et al., Genes Chromosomes Cancer, (20170000), vol. 56, no. 10, pages 730 - 749
    - SHI et al., J Transl Med., (20160000), vol. 14, no. 1, page 339
    - GALLO et al., Cytokine Growth Factor Rev, (20150000), vol. 26, pages 425 - 449
    - DAVIES et al., J. Cancer Res., (20050000), vol. 65, page 7591
    - KELLEHER et al., Carcinogenesis, (20130000), vol. 34, page 2198
    - CAZIER et al., Nat. Commun., (20140000), vol. 5, page 3756
    - LIU et al., Genet. Mo/. Res., (20140000), vol. 13, page 1109
    - TRUDEL et al., Blood, (20060000), vol. 107, page 4039
    - LIAO et al., Cancer Res, (20130000), vol. 73, pages 5195 - 5205
    - MARTINCORENA et al., Science, (20150000), vol. 348, page 880
    - RIVERA et al., Acta. Neuropathol, (20160000), vol. 131, no. 6, pages 847 - 63
    - LO IACONO et al., Oncotarget., (20160000), vol. 7, no. 12, pages 14394 - 404
    - LI et al., Hum. Pathol, (20160000), vol. 55, pages 143 - 50
    - YOZA et al., Genes Cells., (20160000), vol. 10, no. 10, pages 1049 - 1058
    - BUNNEY et al., EbioMedicine, (20150000), vol. 2, no. 3, pages 194 - 204
    - BYRON et al., Neoplasia, (20130000), vol. 15, no. 8, pages 975 - 88
    - THUSSBAS et al., J. Clin. Oneal., (20060000), vol. 24, no. 23, pages 3747 - 55
    - CHELL et al., Oncogene, (20130000), vol. 32, no. 25, pages 3059 - 70
    - TANIZAKI et al., Cancer Res, (20180000), vol. 78, no. 19, pages 5668 - 5679
    - YANG et al., EBioMedicine, no. 18, pages S2352 - 3964
    - DE MATTOS-ARRUDA et al., Oncotarget, (20180000), vol. 9, no. 29, pages 20617 - 20630
    - STONE et al., Acta Neuropathol, (20170000), vol. 135, no. 1, pages 115 - 129
    - OLIVEIRA et al., J Exp Clin Cancer Res, (20180000), vol. 37, no. 1, page 84
    - CHA et al., Mo/Oneal, (20180000), vol. 12, no. 7, pages 993 - 1003
    - IKEDA et al., Oncologist, (20180000), vol. 23, no. 5, pages 586 - 593
    - PELAEZ-GARDA et al., PLoS One, (20130000), vol. 8, no. 5, page e63695
    - WELANDER et al., World J Surg, (20180000), vol. 42, no. 2, pages 482 - 489
    - CHANDRANI et al., Ann Oneal, (20170000), vol. 28, no. 3, pages 597 - 603
    - DALIN et al., Nat Commun, (20170000), vol. 8, no. 1, page 1197
    - TAURIN et al., Intl Gynecol Cancer, (20180000), vol. 28, no. 1, pages 152 - 160
    - HAUGH et al., J Invest Dermatol, (20180000), vol. 138, no. 2, pages 384 - 393
    - GREENMAN et al., Nature, (20070000), vol. 446, no. 7132, pages 153 - 158
    - HELSTEN et al., Clin Cancer Res, (20160000), vol. 22, no. 1, pages 259 - 267
    - KIM et al., BMC Urol, (20180000), vol. 18, page 68
    - JUSAKUL et al., Cancer Discov, (20170000), vol. 7, no. 10, pages 1116 - 1135
    - PREMOV et al., Oncogene, (20170000), vol. 36, no. 22, pages 3168 - 3177
    - GEELVINK et al., Int J Mol Sci, (20180000), vol. 19, no. 9, page E2548
    - LEE et al., Exp TherMed, (20180000), vol. 16, no. 2, pages 1343 - 1349
    - CHESI et al., Blood, (20010000), vol. 97, no. 3, pages 729 - 736
    - GE et al., Am J Cancer Res, (20170000), vol. 7, no. 7, pages 1540 - 1553
    - JIAO et al., Nat Genet, (20130000), vol. 45, no. 12, pages 1470 - 1473
    - GUYARD et al., Respir Res., (20180000), vol. 18, no. 1, page 120
    - PAIK et al., Clin Cancer Res., (20170000), vol. 23, no. 18, pages 5366 - 5373
    - ROY et al., ModPatho/., (20170000), vol. 30, no. 8, pages 1133 - 1143
    - HOANG et al., Sci TranslMed, vol. 5, no. 197, pages 197 - 102
    - KIM et al., Ann Oneal., vol. 28, no. 6, pages 1250 - 1259
    - YONG-XING et al., Hum. Mol. Genet., (20000000), vol. 9, no. 13, pages 2001 - 2008
    - EEVA-MARIA LAITINEN et al., PLoS One, (20120000), vol. 7, no. 6, page e39450
    - HART et al., Oncogene, (20000000), vol. 19, no. 29, pages 3309 - 3320
    - SHIANG et al., Cell, (19940000), vol. 76, pages 335 - 342
    - ROSSEAU et al., Nature, (19940000), vol. 371, pages 252 - 254
    - TAVORMINA et al., Nature Genet, (19950000), vol. 10, pages 165 - 172
    - REARDON et al., Nature Genet, (19940000), vol. 8, pages 275 - 279
    - YE et al., Plast. Reconstr. Surg., (20160000), vol. 137, no. 3, pages 952 - 61
    - BELLUS et al., Am. J. Med. Genet., (19990000), vol. 85, no. 1, pages 53 - 65
    - NAGAHARA et al., Clin. Pediatr. Endocrinol., (20160000), vol. 25, no. 3, pages 103 - 106
    - HIBBERD et al., Am. J. Med. Genet. A., doi: 10.1002/ajmg.a.37862, page 2016
    - DIAS et al., Exp. Mol. Pathol., (20160000), vol. 101, no. 1, pages 116 - 23
    - LIN et al., Mol. Med. Rep., (20160000), vol. 14, no. 3, pages 1941 - 6
    - BARNETT et al., Hum. Mutat., (20160000), vol. 37, no. 9, pages 955 - 63
    - KRSTEVSKA-KONSTANTINOVA et al., Med. Arch., (20160000), vol. 70, no. 2, pages 148 - 50
    - RON et al., Am. J. Case Rep., (20160000), vol. 15, no. 17, pages 254 - 8
    - FERNANDES et al., Am. J. Med. Genet. A., (20160000), vol. 170A, no. 7, pages 1908 - 11
    - BENNETT et al., Am. J. Hum. Genet., (20160000), vol. 98, no. 3, pages 579 - 87
    - LCHIYAMA et al., J. Eur. Acad. Dermatol. Venereal., (20160000), vol. 30, no. 3, pages 442 - 5
    - ZHAO et al., Int. J. Clin. Exp. Med., (20150000), vol. 8, no. 10, pages 19241 - 9
    - LEGEAI-MALLET, Endocr. Dev., (20160000), vol. 30, pages 98 - 105
    - TAKAGI, Am. J. Med. Genet. A., (20150000), vol. 167A, no. 11, pages 2851 - 4
    - GONCALVES, Fertil. Steril., (20150000), vol. 104, no. 5, pages 1261 - 7
    - SARABIPOUR et al., J. Mol. Biol., (20160000), vol. 428, no. 20, pages 3903 - 3910
    - MAZEN et al., Sex Dev., (20160000), vol. 10, no. 1, pages 16 - 22
    - TAYLAN et al., J Allergy Clin lmmunol, (20150000), vol. 136, no. 2, pages 507 - 9
    - KANT et al., EuroJourn Endocrinol, (20150000), vol. 172, no. 6, pages 763 - 770
    - GONZALEZ-DEL ANGEL et al., Am Jmed Genet A, (20180000), vol. 176, no. 1, pages 161 - 166
    - LEIDENG, IntJBiol Sci, (20170000), vol. 13, no. 9, pages 1163 - 1171
    - LAJEUNIE et al., Eur JHum Genet, (20060000), vol. 14, no. 3, pages 289 - 298
    - KARADIMAS et al., PrenatDiagn, (20060000), vol. 26, no. 3, pages 258 - 261
    - LBRAHIMI et al., Hum Mol Genet, (20040000), vol. 13, no. 19, pages 2313 - 2324
    - TRARBACH et al., J Clin Endocrinol Metab., (20060000), vol. 91, no. 10, pages 4006 - 4012
    - DODE et al., Nat Genet, (20030000), vol. 33, no. 4, pages 463 - 465
    - TURNERGROSE, Nat. Rev. Cancer, (20100000), vol. 10, no. 2, pages 116 - 129
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.