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Extract from the Register of European Patents

EP About this file: EP3843751

EP3843751 - COMBINATION PRODUCT OF A BCL-2/BCL-XL INHIBITOR AND A CHEMOTHERAPEUTIC AGENT AND USE THEREOF IN THE PREVENTION AND/OR TREATMENT OF DISEASES [Right-click to bookmark this link]
StatusThe patent has been granted
Status updated on  23.02.2024
Database last updated on 24.08.2024
FormerGrant of patent is intended
Status updated on  18.10.2023
FormerRequest for examination was made
Status updated on  04.06.2021
FormerThe international publication has been made
Status updated on  05.02.2021
Most recent event   Tooltip08.08.2024Lapse of the patent in a contracting state
New state(s): SE
published on 11.09.2024 [2024/37]
Applicant(s)For all designated states
Ascentage Pharma (Suzhou) Co., Ltd.
Unit 701, Building B7, 218 Xinghu Street
Suzhou Industrial Park
Suzhou, Jiangsu 215000 / CN
For all designated states
Ascentage Pharma Group Corp Limited
9/F, Wah Yuen Building
149 Queen's Road Central
Hong Kong / HK
[2023/46]
Former [2021/27]For all designated states
Ascentage Pharma (Suzhou) Co., Ltd.
Unit 701, Building B7, 218 Xinghu Street
Suzhou Industrial Park
Suzhou, Jiangsu 215000 / CN
For all designated states
Ascentage Pharma Group Corp Limited
9/F., Wah Yuen Building
149 Queen's Road Central
Hong Kong / CN
Inventor(s)01 / YANG, Dajun
Unit 701, Building B7 218 Xinghu Street, Suzhou
Industrial Park
Suzhou, Jiangsu 215000 / CN
02 / ZHAI, Yifan
Unit 701, Building B7 218 Xinghu Street, Suzhou
Industrial Park
Suzhou, Jiangsu 215000 / CN
03 / FANG, Douglas Dong
Unit 701, Building B7 218 Xinghu Street, Suzhou
Industrial Park
Suzhou, Jiangsu 215000 / CN
04 / TANG, Qiuqiong
Unit 701, Building B7 218 Xinghu Street, Suzhou
Industrial Park
Suzhou, Jiangsu 215000 / CN
 [2021/27]
Representative(s)Lavoix
Bayerstraße 83
80335 München / DE
[2021/27]
Application number, filing date20847777.830.07.2020
[2021/27]
WO2020CN105810
Priority number, dateWO2019CN9862531.07.2019         Original published format: PCT/CN2019/098625
CN20201063108903.07.2020         Original published format: CN202010631089
[2021/27]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021018240
Date:04.02.2021
Language:EN
[2021/05]
Type: A1 Application with search report 
No.:EP3843751
Date:07.07.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 04.02.2021 takes the place of the publication of the European patent application.
[2021/27]
Type: B1 Patent specification 
No.:EP3843751
Date:27.03.2024
Language:EN
[2024/13]
Search report(s)International search report - published on:CN04.02.2021
(Supplementary) European search report - dispatched on:EP14.04.2022
ClassificationIPC:A61K31/496, A61K31/55, A61P35/00, A61P35/02, A61P35/04
[2023/44]
CPC:
A61P35/00 (EP,CN); A61K45/06 (EP,CN,US); A61K31/55 (EP,CN,US);
A61K31/496 (EP,CN,US); A61K31/635 (CN,US); A61K31/675 (CN,US);
A61P35/02 (EP,CN,US); A61P35/04 (EP) (-)
C-Set:
A61K31/496, A61K2300/00 (CN,EP);
A61K31/55, A61K2300/00 (EP,CN);
A61K31/635, A61K2300/00 (CN);
A61K31/675, A61K2300/00 (CN)
Former IPC [2022/19]A61K31/675, A61K31/496, A61K31/337, A61K31/282, A61K31/4745, A61K31/55, A61K31/635, A61P35/00, A61P35/02, A61P35/04, A61K45/06
Former IPC [2021/27]A61K31/675, A61K31/496, A61K31/337, A61K31/282, A61K31/4745, A61P35/00, A61P35/02, A61P35/04
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/27]
Extension statesBANot yet paid
MENot yet paid
Validation statesKHNot yet paid
MANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:KOMBINATIONSPRODUKT AUS BCL-2/BCL-XL-INHIBITOR UND CHEMOTHERAPEUTIKUM UND VERWENDUNG DAVON ZUR VORBEUGUNG UND/ODER BEHANDLUNG VON ERKRANKUNGEN[2021/27]
English:COMBINATION PRODUCT OF A BCL-2/BCL-XL INHIBITOR AND A CHEMOTHERAPEUTIC AGENT AND USE THEREOF IN THE PREVENTION AND/OR TREATMENT OF DISEASES[2021/27]
French:PRODUIT ASSOCIANT UN INHIBITEUR DE BCL-2/BCL-XL ET UN AGENT CHIMIOTHÉRAPEUTIQUE, ET UTILISATION ASSOCIÉE DANS LA PRÉVENTION ET/OU LE TRAITEMENT DE MALADIES[2021/27]
Entry into regional phase31.03.2021National basic fee paid 
31.03.2021Search fee paid 
31.03.2021Designation fee(s) paid 
31.03.2021Examination fee paid 
Examination procedure31.03.2021Examination requested  [2021/27]
25.10.2022Amendment by applicant (claims and/or description)
19.10.2023Communication of intention to grant the patent
15.02.2024Fee for grant paid
15.02.2024Fee for publishing/printing paid
15.02.2024Receipt of the translation of the claim(s)
Fees paidRenewal fee
10.06.2022Renewal fee patent year 03
12.06.2023Renewal fee patent year 04
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipBG27.03.2024
FI27.03.2024
HR27.03.2024
LT27.03.2024
LV27.03.2024
SE27.03.2024
NO27.06.2024
RS27.06.2024
GR28.06.2024
[2024/37]
Former [2024/36]BG27.03.2024
FI27.03.2024
HR27.03.2024
LT27.03.2024
LV27.03.2024
NO27.06.2024
RS27.06.2024
GR28.06.2024
Former [2024/35]BG27.03.2024
FI27.03.2024
HR27.03.2024
LT27.03.2024
NO27.06.2024
RS27.06.2024
GR28.06.2024
Former [2024/33]LT27.03.2024
NO27.06.2024
Documents cited:Search[X]  - KLANOVA MAGDALENA ET AL, "Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma", CLINICAL CANCER RESEARCH, US, vol. 22, no. 5, doi:10.1158/1078-0432.CCR-15-1191, ISSN 1078-0432, (20160301), pages 1138 - 1149, INTERNET, URL: https://watermark.silverchair.com/1138.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA_swggP3BgkqhkiG9w0BBwagggPoMIID5AIBADCCA90GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM681oV1tZGhcReAVyAgEQgIIDrhfBnZKT9C4nKBtHY0qroBYn1qzuJeDdrVUCOIUQF5WkucEmCtWbDpe0867e46PuyGgs5BzxhE6yFxdp9CLHCo029dvgTb5, (20220401), XP055908513 [X] 1,2,5-14 * abstract * * page 1144; figure 4 * * page 1140, column left, paragraph first *

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-15-1191
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.