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Extract from the Register of European Patents

EP About this file: EP4021912

EP4021912 - PRODRUGS OF THE TYROSINE KINASE INHIBITOR FOR TREATING CANCER [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  03.06.2022
Database last updated on 07.10.2024
FormerThe international publication has been made
Status updated on  05.03.2021
Most recent event   Tooltip21.08.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Risen (Suzhou) Pharma Tech Co., Ltd.
Suite 501-Building G
388 Ruoshui Road
Suzhou, Jiangsu 215000 / CN
[2022/27]
Inventor(s)01 / LU, Jiasheng
No. 559, 1357 Huqingping Highway Shanghai
Shanghai 201702 / CN
02 / GU, Jiamin
Room 507, 508 Jinmen Road
Suzhou, Jiangsu 215000 / CN
03 / CHEN, Gang
388 Ruoshui Street, Suite 501 - Building G
Suzhou, Jiangsu 215000 / CN
04 / ZHANG, Qiguo
388 Ruoshui Street, Suite 501 - Building G
Suzhou, Jiangsu 215000 / CN
05 / SUN, Chengyong
388 Ruoshui Street, Suite 501 - Building G
Suzhou, Jiangsu 215000 / CN
06 / KONG, Xianqi
12, rue Papillon Dollard-des-Ormeaux
Québec H9B 3J7 / CA
 [2022/27]
Representative(s)Høiberg P/S
Adelgade 12
1304 Copenhagen K / DK
[2022/27]
Application number, filing date20857153.928.08.2020
[2022/27]
WO2020CA51177
Priority number, dateCN20191081750530.08.2019         Original published format: CN201910817505
CN20191081867530.08.2019         Original published format: CN201910818675
CN20191081877930.08.2019         Original published format: CN201910818779
US202062994364P25.03.2020         Original published format: US 202062994364 P
[2022/27]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021035360
Date:04.03.2021
Language:EN
[2021/09]
Type: A1 Application with search report 
No.:EP4021912
Date:06.07.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 04.03.2021 takes the place of the publication of the European patent application.
[2022/27]
Search report(s)International search report - published on:CA04.03.2021
(Supplementary) European search report - dispatched on:EP25.07.2023
ClassificationIPC:C07F9/6558, A61K31/4439, A61K31/675, A61P35/00, C07D401/06, C07D401/14, C07D405/12
[2023/34]
CPC:
C07F9/65583 (EP,IL); A61P35/00 (EP,IL); C07D401/06 (EP,IL);
C07D401/14 (EP,IL); C07D405/12 (EP,IL); Y02P20/55 (EP)
Former IPC [2022/27]C07F9/6558, A61K31/4439, A61K31/675, A61P35/00, C07D401/06, C07D401/14
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/27]
TitleGerman:PRODRUGS DES TYROSINKINASEINHIBITORS ZUR BEHANDLUNG VON KREBS[2022/27]
English:PRODRUGS OF THE TYROSINE KINASE INHIBITOR FOR TREATING CANCER[2022/27]
French:PROMÉDICAMENTS DE L'INHIBITEUR DE TYROSINE KINASE POUR LE TRAITEMENT DU CANCER[2022/27]
Entry into regional phase22.03.2022National basic fee paid 
22.03.2022Search fee paid 
22.03.2022Designation fee(s) paid 
22.03.2022Examination fee paid 
Examination procedure22.03.2022Examination requested  [2022/27]
21.02.2024Amendment by applicant (claims and/or description)
21.02.2024Date on which the examining division has become responsible
Fees paidRenewal fee
22.03.2022Renewal fee patent year 03
16.08.2023Renewal fee patent year 04
21.08.2024Renewal fee patent year 05
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Documents cited:Search[XI]CN106317017  (LI JIANCHENG) [X] 1,2,9,11-14 * compounds 1, 2 and the de-boc variant of compound 2 on page 5 * * Use of compounds as prodrug of the parent drug Axitinib and for therapeutic treatment of ophthalmic diseases, where modified pharmacokinetics and solubility are required: see paragraphs 4-8 *[I] 3-8,15
International search[Y]WO0102369  (AGOURON PHARMA [US]) [Y] 13-26, 31-37 **see the whole document** D5: CHEKAL B. P. et al., "Development of an Efficient Pd-Catalyzed Coupling Process for *;
 [X]CN106336397  (GUO MINGSHAN) [X] 1-12,27-29 **see claims 1-5 and the examples**;
 [X]CN106478596  (LI JIANCHENG) [X] 1-5, 10-12, 27-29 **see claims 1-4, 6-9 and the examples**;
 [PX]WO2019196945  (HINOVA PHARMACEUTICALS INC [CN]) [PX] 1-5 **see p. 8**;
 [X]  - Chekal et al., "Development of an Efficient Pd-Catalyzed Coupling Process for Axitinib", Organic Process Research & Development, (20140000), vol. 18, no. 1, pages 266 - 274, XP055636708 [X] 1-5 **see scheme 6**

DOI:   http://dx.doi.org/10.1021/op400088k
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.