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Extract from the Register of European Patents

EP About this file: EP4049724

EP4049724 - PHARMACEUTICAL COMPOSITION FOR PROTECTING CARTILAGE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  23.02.2024
Database last updated on 02.11.2024
FormerRequest for examination was made
Status updated on  29.07.2022
FormerThe international publication has been made
Status updated on  01.05.2021
Most recent event   Tooltip23.02.2024Application deemed to be withdrawnpublished on 27.03.2024  [2024/13]
Applicant(s)For all designated states
Kyoto University
36-1, Yoshida-honmachi
Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
For all designated states
Kyoto Drug Discovery & Development Co., Ltd.
302, Saito Bio Hills Center, 7-18
Saitoasagi 7-chome
Ibaraki-shi, Osaka, 567-0085 / JP
[2022/35]
Inventor(s)01 / NISHITANI, Kohei
c/o Kyoto University, 36-1, Yoshida-honmachi,
Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
02 / KAKIZUKA, Akira
c/o Kyoto University, 36-1, Yoshida-honmachi,
Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
03 / IKEDA, Hanako
c/o Kyoto University, 36-1, Yoshida-honmachi,
Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
04 / MATSUDA, Shuichi
c/o Kyoto University, 36-1, Yoshida-honmachi,
Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
05 / IWAI, Sachiko
c/o Kyoto University, 36-1, Yoshida-honmachi,
Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
06 / SAITO, Motoo
c/o Kyoto University, 36-1, Yoshida-honmachi,
Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
07 / MUSASHI, Kunihiro
c/o KYOTO DRUG DISCOVERY & DEVELOPMENT CO., LTD.
302, Saito Bio Hills Center, 7-18, Saitoasagi 7-
chome
Ibaraki-shi, Osaka 567-0085 / JP
 [2022/35]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[2022/35]
Application number, filing date20879043.623.10.2020
[2022/35]
WO2020JP39896
Priority number, dateJP2019019332924.10.2019         Original published format: JP 2019193329
[2022/35]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021079983
Date:29.04.2021
Language:JA
[2021/17]
Type: A1 Application with search report 
No.:EP4049724
Date:31.08.2022
Language:EN
[2022/35]
Search report(s)International search report - published on:JP29.04.2021
(Supplementary) European search report - dispatched on:EP03.04.2023
ClassificationIPC:A61P19/02, A61P19/04, A61P43/00, A61K31/655
[2022/35]
CPC:
A61K31/655 (EP,CN,KR,US); A61P19/00 (CN); A61P19/02 (EP,CN,KR,US);
A61P19/04 (EP,CN,KR); A61P43/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/35]
TitleGerman:PHARMAZEUTISCHE ZUSAMMENSETZUNG ZUM SCHUTZ VON KNORPEL[2022/35]
English:PHARMACEUTICAL COMPOSITION FOR PROTECTING CARTILAGE[2022/35]
French:COMPOSITION PHARMACEUTIQUE POUR PROTÉGER LE CARTILAGE[2022/35]
Entry into regional phase04.05.2022Translation filed 
04.05.2022National basic fee paid 
04.05.2022Search fee paid 
04.05.2022Designation fee(s) paid 
04.05.2022Examination fee paid 
Examination procedure04.05.2022Examination requested  [2022/35]
02.12.2022Amendment by applicant (claims and/or description)
31.10.2023Application deemed to be withdrawn, date of legal effect  [2024/13]
21.11.2023Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2024/13]
Fees paidRenewal fee
18.10.2022Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
31.10.202304   M06   Not yet paid
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Documents cited:Search[A]WO2010038153  (UNIV BRITISH COLUMBIA [CA], et al) [A] 1-14 * claim 4 *;
 [X]EP2599771  (DAITO CHEMIX CORP [JP], et al) [X] 1-14 * page 20, paragraphs 100, 103; table 1; compound 49 *;
 [X]EP3042658  (UNIV KYOTO [JP]) [X] 1-4 * page 13; claim 1; table 1; compound 32 *;
 [A]  - HELLIWELL P. S., "OSTEOARTHRITIS AND PAGET'S DISEASE", RHEUMATOLOGY, GB, vol. 34, no. 11, doi:10.1093/rheumatology/34.11.1061, ISSN 1462-0324, (19950101), pages 1061 - 1063, URL: http://dx.doi.org/10.1093/rheumatology/34.11.1061, XP093034062 [A] 1-14 * abstract *

DOI:   http://dx.doi.org/10.1093/rheumatology/34.11.1061
 [A]  - YAN MOQI ET AL, "The role of leptin in osteoarthritis", MEDICINE, US, (20180401), vol. 97, no. 14, doi:10.1097/MD.0000000000010257, ISSN 0025-7974, page e0257, XP093034066 [A] 1-14 * abstract *

DOI:   http://dx.doi.org/10.1097/MD.0000000000010257
 [A]  - RANNOU F ET AL, "Cartilage breakdown in rheumatoid arthritis", JOINT BONE SPINE, ELSEVIER, AMSTERDAM, NL, vol. 73, no. 1, doi:10.1016/J.JBSPIN.2004.12.013, ISSN 1297-319X, (20060101), pages 29 - 36, (20060101), XP028072811 [A] 1-14 * abstract *

DOI:   http://dx.doi.org/10.1016/j.jbspin.2004.12.013
International search[A]WO2012014994  (DAITO CHEMIX CORP [JP], et al) [A] 1-11 * 1, 7 - 1 5, 0003, 1 ~ 3 *;
 [A]WO2012043891  (DAITO CHEMIX CORP [JP], et al) [A] 1-11 * 1 - 3 *;
 [A]WO2014129495  (UNIV KYOTO [JP]) [A] 1-11 * 1 - 5 *;
 [A]WO2015033981  (UNIV KYOTO [JP]) [A] 1-11 * 1-22 *;
 [A]WO2015129809  (UNIV KYOTO [JP]) [A] 1-11 * 1 - 5 *;
 [A]WO2019131720  (UNIV KYOTO [JP], et al) [A] 1-11 * 1 - 4 *;
 [A]  - Kakizuka, Akira, "Breakdown of ATP homeostasis and diseases", Journal of clinical and experimental medicine, JP , (20150101), vol. 254, no. 5, ISSN 0039-2359, pages 361 - 367, XP009536049 [A] 1-11
 [A]  - Bartolome Fernando; Wu Hsiu-Chuan; Burchell Victoria S; Preza Elisavet; Wray Selina; Mahoney Colin J; Fox Nick C; Calvo Andrea; Canosa Antonio; Moglia Cristina; Mandrioli Jessica; Chiò Adriano; Orrell Richard W; Houlden Henry; Hardy John; Abramov Andrey Y; Plun-Favreau Helene, "Pathogenic VCP Mutations Induce Mitochondrial Uncoupling and Reduced ATP Levels", Neuron, (20130000), vol. 78, no. 1, pages 57 - 64, XP028547116 [A] 1-11 * SUMMARY *

DOI:   http://dx.doi.org/10.1016/j.neuron.2013.02.028
 [A]  - Blythe Emily E., Olson Kristine C., Chau Vincent, Deshaies Raymond J., "Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP . NPLOC4 . UFDIL is enhanced by a mutation that causes multisystem proteinopathy", PNAS, (20170000), vol. 114, no. 22, doi:10.1073/pnas.1706205114, pages E4380 - E4388, XP055820663 [A] 1-11 * Abstract, Introduction *

DOI:   http://dx.doi.org/10.1073/pnas.1706205114
by applicantWO2012014994
 WO2012043891
 WO2014129495
 WO2015033981
 WO2015129809
 WO2019131720
 JP2019193329
    - YAZICI Y et al., Osteoarthritis Cartilage, (20171000), vol. 25, no. 10, pages 1598 - 1606
    - SAKATA S et al., J Orthop Res, (20150300), vol. 33, no. 3, pages 359 - 65
    - J Cell Biol, (19960400), vol. 133, no. 2, pages 457 - 68
    - M. UDO et al., Osteoarthritis Cartilage, (20160000), vol. 24, pages 1284 - 91
    - "Osteoarthritis cartilage histopathology", Osteoarthritis Cartilage, (20060100), vol. 14, no. 1, pages 13 - 29
    - WU PSANDELL L et al., Arthritis Rheumatol, (20140000), vol. 66, no. 5, pages 1256 - 65
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.