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Extract from the Register of European Patents

EP About this file: EP4056580

EP4056580 - METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  12.08.2022
Database last updated on 02.11.2024
FormerThe international publication has been made
Status updated on  14.05.2021
Most recent event   Tooltip24.05.2024Amendment by applicant 
Applicant(s)For all designated states
CHUGAI SEIYAKU KABUSHIKI KAISHA
5-1, 5-chome Ukima
Kita-ku
Tokyo 115-8543 / JP
[2022/37]
Inventor(s)01 / NOMURA, Kenichi
c/o CHUGAI SEIYAKU KABUSHIKI KAISHA,
135, Komakado 1-chome
Gotemba-shi, Shizuoka 412-8513 / JP
02 / MORITA, Yuya
c/o CHUGAI SEIYAKU KABUSHIKI KAISHA
200, Kajiwara
Kamakura-shi, Kanagawa 247-8530 / JP
03 / HASHIMOTO, Satoshi
c/o CHUGAI SEIYAKU KABUSHIKI KAISHA,
135 Komakado 1-chome
Gotemba-shi, Shizuoka 412-8513 / JP
 [2022/37]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstraße 3
81675 München / DE
[2022/37]
Application number, filing date20884129.605.11.2020
[2022/37]
WO2020JP41279
Priority number, dateJP2019020240807.11.2019         Original published format: JP 2019202408
[2022/37]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021090856
Date:14.05.2021
Language:JA
[2021/19]
Type: A1 Application with search report 
No.:EP4056580
Date:14.09.2022
Language:EN
[2022/37]
Search report(s)International search report - published on:JP14.05.2021
(Supplementary) European search report - dispatched on:EP08.11.2023
ClassificationIPC:C07K1/04, C07K1/06, C07K7/64
[2022/37]
CPC:
C07K7/64 (EP,CN,KR); C07K1/061 (KR); C07K1/04 (CN,KR);
C07K1/063 (EP,US); C07K1/026 (US); C07K1/06 (CN);
C07K1/1077 (EP); C07K5/0808 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/37]
TitleGerman:VERFAHREN ZUM HERSTELLEN EINER PEPTIDVERBINDUNG, DIE EINE STERISCH GEHINDERTE AMINOSÄURE UMFASST[2022/37]
English:METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID[2022/37]
French:PROCÉDÉ DE FABRICATION DE COMPOSÉ PEPTIDE CONTENANT UN ACIDE AMINÉ À ENCOMBREMENT STÉRIQUE IMPORTANT[2022/37]
Entry into regional phase26.04.2022Translation filed 
25.05.2022National basic fee paid 
25.05.2022Search fee paid 
25.05.2022Designation fee(s) paid 
25.05.2022Examination fee paid 
Examination procedure25.05.2022Examination requested  [2022/37]
23.05.2024Amendment by applicant (claims and/or description)
23.05.2024Date on which the examining division has become responsible
Fees paidRenewal fee
23.11.2022Renewal fee patent year 03
22.11.2023Renewal fee patent year 04
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[Y]  - DI GIOIA M. LUISA ET AL, "N -Methylation of Peptides on Selected Positions during the Elongation of the Peptide Chain in Solution Phase", THE JOURNAL OF ORGANIC CHEMISTRY, (20050501), vol. 70, no. 10, doi:10.1021/jo0478959, ISSN 0022-3263, pages 3892 - 3897, XP093095550 [Y] 1-28 * Title; abstract; scheme 2, 3, 4, 5; tables 1, 2, 3 *

DOI:   http://dx.doi.org/10.1021/jo0478959
 [Y]  - ANDREAS F.B. RäDER ET AL, "Improving oral bioavailability of cyclic peptides by N -methylation", BIOORGANIC & MEDICINAL CHEMISTRY, AMSTERDAM, NL, (20170831), vol. 26, no. 10, doi:10.1016/j.bmc.2017.08.031, ISSN 0968-0896, pages 2766 - 2773, XP055598620 [Y] 1-28 * Title; Abstract; Scheme 1 *

DOI:   http://dx.doi.org/10.1016/j.bmc.2017.08.031
 [YD]  - TURNER RUSHIA A. ET AL, "Selective, On-Resin N -Methylation of Peptide N -Trifluoroacetamides", ORGANIC LETTERS, US, (20131004), vol. 15, no. 19, doi:10.1021/ol402341u, ISSN 1523-7060, pages 5012 - 5015, XP093095443 [YD] 1-28 * Title; Abstract; Scheme 3 *

DOI:   http://dx.doi.org/10.1021/ol402341u
 [YD]  - MILLER S C ET AL, "SITE-SELECTIVE N-METHYLATION OF PEPTIDES ON SOLID SUPPORT", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, (19970101), vol. 119, doi:10.1021/JA9635443, ISSN 0002-7863, XP001128157 [YD] 1-28 * Title; Abstract; Scheme 1; Table 1 *

DOI:   http://dx.doi.org/10.1021/ja9635443
International search[A]JP2015509940  [A] 1-28;
 [A]  - Brown Zachary Z., Schafmeister Christian E., "Exploiting an inherent neighboring group effect of alpha- amino acids to synthes Z.ize extremely hindered dipeptides", Journal of the American Chemical Society, (20080000), vol. 130, no. 44, doi:10.1021/ ja806063k, pages 14382 - 14383, XP055821615 [A] 1-28 * 2, 1 *

DOI:   http://dx.doi.org/10.1021/ja806063k
 [A]  - CARPINO, L. A. et al., "Protected amino acid chlorides vs. protected amino acid fluorides: reactivity comparisons", Tetrahedron Letters, (19980000), vol. 39, no. 3 / 4, doi:10.1016/S0040-4039(97)10504-4, pages 241 - 244, XP004100931 [A] 1-28

DOI:   http://dx.doi.org/10.1016/S0040-4039(97)10504-4
 [A]  - Brandt Wolfgang, Herberg Thomas, Wessjohann Ludger, "Systematic conformational investigations of peptoids and peptoid-peptide chimeras", Biopolymers (Peptide Science, (20110000), vol. 96, no. 5, doi:10.1002/bip.21620, pages 651 - 668, XP055821617 [A] 1-28 * 1 *

DOI:   http://dx.doi.org/10.1002/bip.21620
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.