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Extract from the Register of European Patents

EP About this file: EP4087583

EP4087583 - ARGINASE INHIBITORS AND METHODS OF USE [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  14.10.2022
Database last updated on 11.09.2024
FormerThe international publication has been made
Status updated on  16.07.2021
Most recent event   Tooltip12.07.2024Amendment by applicant 
Applicant(s)For all designated states
Merck Sharp & Dohme LLC
126 East Lincoln Avenue
Rahway, New Jersey 07065 / US
[2022/46]
Inventor(s)01 / ACHAB, Abdelghani Abe
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
02 / CHILDERS, Matthew, L.
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
03 / FISCHER, Christian
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
04 / GATHIAKA, Symon
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
05 / LI, Derun
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
06 / LU, Min
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
07 / PALANI, Anandan
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
08 / PALTE, Rachel, L.
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
09 / PU, Qinglin
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
10 / SLOMAN, David, L.
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
11 / ZHANG, Hongjun
254 Park Street
Boston, Massachusetts 02132 / US
 [2022/46]
Representative(s)Merck Sharp & Dohme LLC
120 Moorgate
London EC2M 6UR / GB
[2022/46]
Application number, filing date20911563.318.12.2020
[2022/46]
WO2020US65798
Priority number, dateUS202062958056P07.01.2020         Original published format: US 202062958056 P
[2022/46]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021141751
Date:15.07.2021
Language:EN
[2021/28]
Type: A1 Application with search report 
No.:EP4087583
Date:16.11.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 15.07.2021 takes the place of the publication of the European patent application.
[2022/46]
Search report(s)International search report - published on:US15.07.2021
(Supplementary) European search report - dispatched on:EP02.01.2024
ClassificationIPC:A61K31/69, A61P35/00, C07F5/02, A61K45/06
[2024/04]
CPC:
C07F5/025 (EP,US); A61K31/69 (EP); A61K45/06 (EP);
A61P35/00 (EP); Y02A50/30 (EP)
C-Set:
A61K31/69, A61K2300/00 (EP)
Former IPC [2022/46]A61K31/69, A61P35/00, C07F5/02
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/46]
TitleGerman:ARGINASE-INHIBITOREN UND VERFAHREN ZUR VERWENDUNG[2022/46]
English:ARGINASE INHIBITORS AND METHODS OF USE[2022/46]
French:INHIBITEURS D'ARGINASE ET MÉTHODES D'UTILISATION[2022/46]
Entry into regional phase08.08.2022National basic fee paid 
08.08.2022Search fee paid 
08.08.2022Designation fee(s) paid 
08.08.2022Examination fee paid 
Examination procedure08.08.2022Examination requested  [2022/46]
11.07.2024Amendment by applicant (claims and/or description)
11.07.2024Date on which the examining division has become responsible
Fees paidRenewal fee
09.12.2022Renewal fee patent year 03
12.12.2023Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]EP3034509  (MARS INC [US]) [X] 1-7,17-21 * page 2, paragraph 0006 * * page 11; compound 11 * * page 12; compound 24 *;
 [X]WO2017075363  (CALITHERA BIOSCIENCES INC [US]) [X] 1-7,17-21 * page 2, paragraph 1 * * page 83; claim 36 *;
 [X]WO2019177873  (MERCK SHARP & DOHME [US], et al) [X] 1-7,17-21 * page 1, paragraph 1 * * page 261; example 9 *;
 [XI]WO2019245890  (MERCK SHARP & DOHME [US], et al) [X] 1-7,10,13,15-21 * page 86, paragraph 1 * * page 1, paragraph 1 * * page 88, paragraph 5 * * page 88, paragraph 3 * * page 89, paragraph 2 * * page 86, paragraph 5 * * page 6; compound I * * page 64; compound IV * * page 65; compound V * * page 68; compound VI * * page 84; compound VII *[I] 11,12,14;
 [E]EP3897622  (MERCK SHARP & DOHME [US]) [E] 1-9,17-21 * page 1, paragraph 1 * * page 101; claims 35,36 *
International search[A]US2017121352  (SJOGREN ERIC B [US], et al) [A] 1-3* ; entire document *;
 [A]US2017319536  (BLASZCZYK ROMAN [PL], et al) [A] 1-3 * ; entire document *;
 [A]WO2019177873  (MERCK SHARP & DOHME [US], et al) [A] 1-3 * ; p66 *;
 [A]  - "1,2-Dioxaspiro[4.5]dec-7-en-4-ylboronic acid", PubChem Compound, U.S. National Library of Medicine, (20120212), Database accession no. CID 87392280, URL: ncbi, XP055840762 [A] 1-3 * ; p2 *
 [A]  - ERB et al., "An Easy Route to (Hetero)arylboronic Acids", Chemistry A European Journal, (20140526), vol. 20, no. 22, pages 6608 - 6612, XP055840759 [A] 1-3 * ; p6611 *

DOI:   http://dx.doi.org/10.1002/chem.201402487
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