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Extract from the Register of European Patents

EP About this file: EP3868374

EP3868374 - USING FATTY ACID SYNTHASE INHIBITORS TO TREAT FIBROSIS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  16.09.2022
Database last updated on 24.08.2024
FormerThe application has been published
Status updated on  23.07.2021
Most recent event   Tooltip16.09.2022Application deemed to be withdrawnpublished on 19.10.2022  [2022/42]
Applicant(s)For all designated states
Mayo Foundation for Medical Education and Research
200 First Street S.W.
Rochester, MN 55905 / US
[2021/34]
Inventor(s)01 / LEOF, Edward B.
4120 Windsor Hills Lane S.W.
Rochester, MN Minnesota 55902 / US
02 / LUPU, Ruth
2167 Hill Place S.W.
Rochester, MN Minnesota 55902-2473 / US
03 / KANG, Jeong-Han
6424 Shetland Drive N.W.
Rochester, MN Minnesota 55901-5661 / US
04 / JUNG, Mi-Yeon
6424 Shetland Drive N.W.
Rochester, MN Minnesota 55901-5661 / US
 [2021/34]
Representative(s)Fish & Richardson P.C.
Highlight Business Towers
Mies-van-der-Rohe-Straße 8
80807 München / DE
[2021/34]
Application number, filing date21150195.222.03.2017
[2021/34]
Priority number, dateUS201662311615P22.03.2016         Original published format: US 201662311615 P
[2021/34]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP3868374
Date:25.08.2021
Language:EN
[2021/34]
Type: A3 Search report 
No.:EP3868374
Date:10.11.2021
Language:EN
[2021/45]
Search report(s)(Supplementary) European search report - dispatched on:EP12.10.2021
ClassificationIPC:A61K31/365, A61K31/34, A61K31/341, A61K31/713, C12N15/11, A61K48/00, A61K38/00, A61P11/00, A61P43/00
[2021/34]
CPC:
A61K31/365 (EP,US); A61K31/341 (EP,US); A61K31/713 (EP,US);
A61P11/00 (EP,US); A61P43/00 (EP,US); C12N15/1137 (EP,US);
C12N2310/14 (EP,US); C12N2310/531 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/34]
TitleGerman:VERWENDUNG VON FETTSÄURESYNTHASEINHIBITOREN ZUR BEHANDLUNG VON FIBROSE[2021/34]
English:USING FATTY ACID SYNTHASE INHIBITORS TO TREAT FIBROSIS[2021/34]
French:UTILISATION D'INHIBITEURS D'ACIDE GRAS SYNTHASE POUR TRAITER LA FIBROSE[2021/34]
Examination procedure11.05.2022Application deemed to be withdrawn, date of legal effect  [2022/42]
01.06.2022Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2022/42]
Parent application(s)   TooltipEP17771043.1  / EP3432879
Fees paidRenewal fee
04.05.2021Renewal fee patent year 03
04.05.2021Renewal fee patent year 04
31.03.2021Renewal fee patent year 05
28.03.2022Renewal fee patent year 06
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Documents cited:Search[X]US2004214804  (GULVE ERIC ARTHUR [US], et al) [X] 1-3 * claims 1, 4-7, 14, 26 *;
 [X]US2010190856  (COLOMER BOSCH RAMON [ES], et al) [X] 1-3,5 * paragraphs [0003] , [00 4] , [ 100] *;
 [A]US2010197708  (TALLEY JOHN JEFFREY [US], et al) [A] 1-3,5,6* the whole document *;
 [X]US2015157634  (BLAZAR BRUCE R [US], et al) [X] 1-3,5 * paragraphs [0020] , [ 167] *;
 [X]  - JOANA RELAT ET AL, "Different fatty acid metabolism effects of (-)-Epigallocatechin-3-Gallate and C75 in Adenocarcinoma lung ca", BMC CANCER, BIOMED CENTRAL, LONDON, GB, (20120706), vol. 12, no. 1, doi:10.1186/1471-2407-12-280, ISSN 1471-2407, page 280, XP021120446 [X] 1-3,5 * abstract *

DOI:   http://dx.doi.org/10.1186/1471-2407-12-280
 [X]  - CONG CHEN ET AL, "4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic Acid (C75), an Inhibitor of Fatty-acid Synthase, Suppresses the Mitochondrial Fatty Acid Synthesis Pathway and Impairs Mitochondrial Function", JOURNAL OF BIOLOGICAL CHEMISTRY, US, (20140613), vol. 289, no. 24, doi:10.1074/jbc.M114.550806, ISSN 0021-9258, pages 17184 - 17194, XP055521476 [X] 1-3,5 * page 17184 *

DOI:   http://dx.doi.org/10.1074/jbc.M114.550806
 [A]  - CAMELIA R BAN ET AL, "Fibrosis in diabetes complications: pathogenic mechanisms and circulating and urinary markers", VASCULAR HEALTH AND RISK MANAGEMENT, NZ, (20080101), vol. 4, no. 3, doi:10.2147/VHRM.S1991, ISSN 1176-6344, pages 575 - 596, XP055521488 [A] 1-3,5,6 * the whole document *

DOI:   http://dx.doi.org/10.2147/VHRM.S1991
by applicant   - ANDRIANIFAHANANA et al., FASEB J, (20130000), vol. 27, no. 11, pages 4444 - 54
    - "NCBI", Database accession no. NP _001274689.1
    - JONES et al., Clin Cancer Res, (20150000), vol. 21, no. 24, pages 5434 - 38
    - "GenBank", Database accession no. NP 004095.4
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.