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Extract from the Register of European Patents

EP About this file: EP3906925

EP3906925 - USE OF FLAP INHIBITORS TO REDUCE NEUROINFLAMMATION MEDIATED INJURY IN THE CENTRAL NERVOUS SYSTEM [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  16.09.2022
Database last updated on 03.01.2025
FormerThe application has been published
Status updated on  08.10.2021
Most recent event   Tooltip16.09.2022Application deemed to be withdrawnpublished on 19.10.2022  [2022/42]
Applicant(s)For all designated states
Bioscience Pharma Partners, LLC
6135 East Harvard Street
Phoenix, AZ 85257 / US
[2021/45]
Inventor(s)01 / HEIDENREICH, Kim A
Denver, 80220 / US
02 / MURPHY, Robert C
Denver, 80231 / US
 [2021/45]
Representative(s)Rudkin, Mairi Ellen
Marks & Clerk LLP The Beacon
176 St Vincent Street
Glasgow G2 5SG / GB
[N/P]
Former [2021/45]Rudkin, Mairi Ellen
Marks & Clerk LLP
Aurora
120 Bothwell Street
Glasgow G2 7JS / GB
Application number, filing date21166657.304.02.2015
[2021/45]
Priority number, dateUS201461935763P04.02.2014         Original published format: US 201461935763 P
[2021/45]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3906925
Date:10.11.2021
Language:EN
[2021/45]
Search report(s)(Supplementary) European search report - dispatched on:EP11.10.2021
ClassificationIPC:A61K31/4709, A61K31/405, A61K31/404, A61K9/00, A61P25/00
[2021/45]
CPC:
A61K31/4709 (EP,US); A61K31/404 (EP,US); A61K31/405 (EP,US);
A61K45/06 (EP,US); A61K9/0043 (EP,US); A61P25/00 (EP)
C-Set:
A61K31/404, A61K2300/00 (US,EP);
A61K31/405, A61K2300/00 (US,EP);
A61K31/4709, A61K2300/00 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/45]
TitleGerman:VERWENDUNG VON FLAP-HEMMERN ZUR VERRINGERUNG VON NERVENENTZÜNDUNGSVERMITTELTEN LÄSIONEN DES ZENTRALEN NERVENSYSTEMS[2021/45]
English:USE OF FLAP INHIBITORS TO REDUCE NEUROINFLAMMATION MEDIATED INJURY IN THE CENTRAL NERVOUS SYSTEM[2021/45]
French:UTILISATION D'INHIBITEURS DE FLAP POUR RÉDUIRE UNE LÉSION MEDIÉE PAR UNE NEURO-INFLAMMATION DANS LE SYSTÈME NERVEUX CENTRAL[2021/45]
Examination procedure11.05.2022Application deemed to be withdrawn, date of legal effect  [2022/42]
01.06.2022Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2022/42]
Parent application(s)   TooltipEP15705756.3  / EP3102209
Fees paidRenewal fee
05.07.2021Renewal fee patent year 03
05.07.2021Renewal fee patent year 04
05.07.2021Renewal fee patent year 05
05.07.2021Renewal fee patent year 06
05.07.2021Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
28.02.202208   M06   Not yet paid
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Documents cited:Search[XI]WO0205825  (BRISTOL MYERS SQUIBB CO [US]) [X] 1-4,6,11-15 * page 1, lines 10-18; claims 7-8, 11-12 * [I] 5,7-10;
 [A]US2013090315  (VANLANDINGHAM JACOB W [US], et al) [A] 1-15 * paragraphs [0063] - [0065] *;
 [XI]US2013310421  (PRATICO DOMENICO [US]) [X] 1-4,6,10-15 * paragraphs [0010] , [0017] , [0042] - [0044] - [0050] - [0051] - [0078]; example 2; claims 1,2,7,10-13,18-22 * [I] 5,7-9;
 [XI]  - C. VOIGT ET AL, "Effect of leukotriene inhibitors on evolution of experimental brain contusions", NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, (20120511), vol. 38, no. 4, doi:10.1111/j.1365-2990.2011.01211.x, ISSN 0305-1846, pages 354 - 366, XP055187126 [X] 1-6,11-15 * abstract * * page 360, column 2, paragraphs 2-3; figures 3,6 * * page 361, column 1, paragraph 3 - column 2, paragraph 2 * * page 363, column 2, paragraph 4 * [I] 7-10

DOI:   http://dx.doi.org/10.1111/j.1365-2990.2011.01211.x
 [XI]  - HÄRTIG WOLFGANG ET AL, "Impact of 5-lipoxygenase inhibitors on the spatiotemporal distribution of inflammatory cells and neuronal COX-2 expression following experimental traumatic brain injury in rats", BRAIN RESEARCH, ELSEVIER, AMSTERDAM, NL, (20121223), vol. 1498, doi:10.1016/J.BRAINRES.2012.12.022, ISSN 0006-8993, pages 69 - 84, XP028577724 [X] 1-6,11-15 * abstract * * page 81, column 2, paragraph 3.5 * [I] 7-10

DOI:   http://dx.doi.org/10.1016/j.brainres.2012.12.022
 [XI]  - YOSHIKAWA K ET AL, "Inhibition of 5-lipoxygenase activity in mice during cuprizone-induced demyelination attenuates neuroinflammation, motor dysfunction and axonal damage", PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, CHURCHILL LIVINGSTONE, EDINBURGH, vol. 85, no. 1, doi:10.1016/J.PLEFA.2011.04.022, ISSN 0952-3278, (20110412), pages 43 - 52, (20110422), XP028373456 [X] 1-6,11-15 * abstract * * page 46, column 2, paragraph 3 - page 48, column 2, paragraph 2 * [I] 7-10

DOI:   http://dx.doi.org/10.1016/j.plefa.2011.04.022
 [XI]  - KAI-HSIANG KANG ET AL, "Protection of dopaminergic neurons by 5-lipoxygenase inhibitor", NEUROPHARMACOLOGY, (20131001), vol. 73, doi:10.1016/j.neuropharm.2013.06.014, ISSN 0028-3908, pages 380 - 387, XP055187128 [X] 1-6,11-15 * abstract * [I] 7-10

DOI:   http://dx.doi.org/10.1016/j.neuropharm.2013.06.014
 [A]  - SANTIAGO FARIAS ET AL, "Injury-Related Production of Cysteinyl Leukotrienes Contributes to Brain Damage following Experimental Traumatic Brain Injury", JOURNAL OF NEUROTRAUMA, (20091101), vol. 26, no. 11, doi:10.1089/neu.2009.0877, ISSN 0897-7151, pages 1977 - 1986, XP055187130 [A] 1-15 * abstract * * page 1984, column 2, paragraph 3; figure 4 *

DOI:   http://dx.doi.org/10.1089/neu.2009.0877
 [A]  - HANSON LEAH R ET AL, "Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease", BMC NEUROSCIENCE, BIOMED CENTRAL, LONDON, GB, (20081210), vol. 9, no. Suppl 3, doi:10.1186/1471-2202-9-S3-S5, ISSN 1471-2202, page S5, XP021042511 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1186/1471-2202-9-S3-S5
 [XP]  - CHELSEA E. CORSER-JENSEN ET AL, "Blocking leukotriene synthesis attenuates the pathophysiology of traumatic brain injury and associated cognitive deficits", EXPERIMENTAL NEUROLOGY, (20140601), vol. 256, doi:10.1016/j.expneurol.2014.03.008, ISSN 0014-4886, pages 7 - 16, XP055187111 [XP] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.expneurol.2014.03.008
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