Extract from the Register of European Patents

EP About this file: EP4112641

EP4112641 - METHODS OF TREATING CANCERS USING PD-1 AXIS BINDING ANTAGONISTS AND ANTI-GPC3 ANTIBODIES [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  10.10.2025
Database last updated on 08.04.2026
FormerExamination is in progress
Status updated on  06.06.2025
FormerRequest for examination was made
Status updated on  07.07.2023
FormerThe application has been published
Status updated on  02.12.2022
Most recent event   Tooltip10.10.2025Withdrawal of applicationpublished on 12.11.2025  [2025/46]
Applicant(s)For all designated states
CHUGAI SEIYAKU KABUSHIKI KAISHA
5-1, 5-chome Ukima
Kita-ku
Tokyo 115-8543 / JP
For all designated states
GENENTECH, INC.
1 DNA Way
South San Francisco, CA 94080 / US
[2023/01]
Inventor(s)01 / ENDO, Mika
Kamakura-shi Kanagawa 247-8530 / JP
02 / KATO, Atsuhiko
Gotemba-shi Shizuoka 412-8513 / JP
03 / OHTOMO, Toshihiko
Tokyo 103-8324 / JP
04 / ADACHI, Kenji
Gotemba-shi Shizuoka 412-8513 / JP
05 / KINOSHITA, Yasuko
Kamakura-shi Kanagawa 247-8530 / JP
 [2023/01]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstraße 3
81675 München / DE
[2023/01]
Application number, filing date21217994.914.03.2017
[2023/01]
Priority number, dateJP2016005142415.03.2016         Original published format: JP 2016051424
[2023/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP4112641
Date:04.01.2023
Language:EN
[2023/01]
Search report(s)(Supplementary) European search report - dispatched on:EP07.12.2022
ClassificationIPC:C07K16/28, C07K16/30, A61K39/395, A61P35/00
[2023/01]
CPC:
C07K16/2827 (EP,CN,KR,US); C07K16/303 (EP,CN,KR,US); A61P35/00 (EP,CN,KR,US);
A61P43/00 (EP); A61K2039/505 (EP,CN,KR); A61K2039/507 (EP,CN,KR);
C07K2317/24 (CN,KR,US); C07K2317/54 (US); C07K2317/55 (US);
C07K2317/56 (US); C07K2317/622 (US); C07K2317/732 (CN,KR);
C07K2317/76 (EP,CN,KR,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/32]
Former [2023/01]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:VERFAHREN ZUR KREBSBEHANDLUNG MIT PD-1-ACHSENBINDENDEN ANTAGONISTEN UND ANTI-GPC3-ANTIKÖRPERN[2023/01]
English:METHODS OF TREATING CANCERS USING PD-1 AXIS BINDING ANTAGONISTS AND ANTI-GPC3 ANTIBODIES[2023/01]
French:PROCÉDÉS DE TRAITEMENT DE CANCERS AU MOYEN D'ANTAGONISTES SE LIANT À L'AXE PD-1 ET D'ANTICORPS ANTI-GPC3[2023/01]
Examination procedure03.07.2023Amendment by applicant (claims and/or description)
03.07.2023Examination requested  [2023/32]
03.07.2023Date on which the examining division has become responsible
11.06.2025Despatch of a communication from the examining division (Time limit: M04)
06.10.2025Application withdrawn by applicant  [2025/46]
Parent application(s)   TooltipEP17715545.4  / EP3430054
Fees paidRenewal fee
28.01.2022Renewal fee patent year 03
28.01.2022Renewal fee patent year 04
28.01.2022Renewal fee patent year 05
28.01.2022Renewal fee patent year 06
14.02.2023Renewal fee patent year 07
15.02.2024Renewal fee patent year 08
14.02.2025Renewal fee patent year 09
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 [I]   YU SAWADA ET AL: "Programmed death-1 blockade enhances the antitumor effects of peptide vaccine-induced peptide-specific cytotoxic T lymphocytes", INTERNATIONAL JOURNAL OF ONCOLOGY, vol. 46, no. 1, 30 October 2014 (2014-10-30), GR, pages 28 - 36, XP055370119, ISSN: 1019-6439, DOI: 10.3892/ijo.2014.2737

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 [A]   A. X. ZHU ET AL: "First-in-Man Phase I Study of GC33, a Novel Recombinant Humanized Antibody Against Glypican-3, in Patients with Advanced Hepatocellular Carcinoma", CLINICAL CANCER RESEARCH, vol. 19, no. 4, 29 January 2013 (2013-01-29), pages 920 - 928, XP055207838, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-12-2616

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-12-2616
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