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Extract from the Register of European Patents

EP About this file: EP4137585

EP4137585 - CANCER INFORMATIVE BIOMARKER SIGNATURE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  05.01.2024
Database last updated on 03.09.2024
FormerThe application has been published
Status updated on  20.01.2023
Most recent event   Tooltip05.01.2024Application deemed to be withdrawnpublished on 07.02.2024  [2024/06]
Applicant(s)For all designated states
Institut D'Investigacions Biomèdiques August Pi I Sunyer - IDIBAPS
C/Rosselló 149-153
08036 Barcelona / ES
For all designated states
Universitat de Barcelona
Centre de Patents de la UB
Baldiri Reixac 4 - Torre D
08028 Barcelona / ES
For all designated states
Hospital Clínic de Barcelona
C/ Villaroel, 170
08036 Barcelona / ES
For all designated states
Consejo Superior de Investigaciones Científicas (CSIC)
C/ Serrano 117
28006 Madrid / ES
For all designated states
Institució Catalana De Recerca I Estudis Avançats (ICREA)
Passeig Lluís Companys, 23
08010 Barcelona / ES
[2023/08]
Inventor(s)01 / MAUREL SANTASUSANA, Joan
BARCELONA / ES
02 / CASCANTE SERRATOSA, Marta
BARCELONA / ES
03 / PEDROSA EGUILAZ, Leire
BARCELONA / ES
04 / FOGUET COLL, Carles
BARCELONA / ES
05 / THOMSON OKATSU, Timothy
BARCELONA / ES
06 / POSTIGO, Antonio
BARCELONA / ES
07 / BENITEZ, Daniel
BARCELONA / ES
08 / CAMPS POLO, Jordi
BARCELONA / ES
 [2023/08]
Representative(s)ZBM Patents - Zea, Barlocci & Markvardsen
Rambla de Catalunya, 123
08008 Barcelona / ES
[N/P]
Former [2023/08]ZBM Patents - Zea, Barlocci & Markvardsen
Rambla Catalunya, 123
08008 Barcelona / ES
Application number, filing date21382772.820.08.2021
[2023/08]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP4137585
Date:22.02.2023
Language:EN
[2023/08]
Search report(s)(Supplementary) European search report - dispatched on:EP24.02.2022
ClassificationIPC:C12Q1/6886
[2023/08]
CPC:
C12Q1/6886 (EP); C12Q2600/106 (EP); C12Q2600/158 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/08]
Extension statesBANot yet paid
MENot yet paid
Validation statesKHNot yet paid
MANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:KREBSINFORMATIONSBIOMARKERSIGNATUR[2023/08]
English:CANCER INFORMATIVE BIOMARKER SIGNATURE[2023/08]
French:SIGNATURE DE BIOMARQUEURS INFORMATIFS DU CANCER[2023/08]
Examination procedure23.08.2023Application deemed to be withdrawn, date of legal effect  [2024/06]
13.09.2023Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2024/06]
Fees paidPenalty fee
Additional fee for renewal fee
31.08.202303   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[IA]WO2019090263  (GENENTECH INC [US], et al) [I] 10-12 * abstract * [A] 1-9,13;
 [IA]  - MARK AYERS ET AL, "IFN-γ-related mRNA profile predicts clinical response to PD-1 blockade", THE JOURNAL OF CLINICAL INVESTIGATION, GB, (20170801), vol. 127, no. 8, doi:10.1172/JCI91190, ISSN 0021-9738, pages 2930 - 2940, XP055608325 [I] 10-12 * abstract * * page 2932, column 2 - page 2933, column 2 * [A] 1-9,13

DOI:   http://dx.doi.org/10.1172/JCI91190
 [IA]  - LI YING ET AL, "A Novel Prognostic Signature Based on Metabolism-Related Genes to Predict Survival and Guide Personalized Treatment for Head and Neck Squamous Carcinoma", FRONTIERS IN ONCOLOGY, (20210614), vol. 11, doi:10.3389/fonc.2021.685026, XP055891972 [I] 10-12 * abstract * * page 9, columns 1-2 * [A] 1-9,13

DOI:   http://dx.doi.org/10.3389/fonc.2021.685026
 [T]  - PEDROSA L, "An immune-metabolic signature correlates with immunesuppressive patterns and with outcome, across tumor types", ANNALS OF ONCOLOGY, (20210901), vol. 32, suppl. 5, doi:10.1016/j.annonc.2021.08.1380, page S847, XP055892357 [T] * abstract *

DOI:   http://dx.doi.org/10.1016/j.annonc.2021.08.1380
by applicantUS7473767
    - BURTIS C. A. et al., Statistical Treatment of Reference Values, (20080000), vol. Chapter 14
    - CRISTESCU R. et al., "Pan-tumor genomic biomarkers for PD-1 checkpoint blockade-based immunotherapy", Science, (20180000), vol. 362, page 3593
    - CHAROENTONG P. et al., "Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade", Cell Rep., (20170103), vol. 18, no. 1, doi:10.1016/j.celrep.2016.12.019, pages 248 - 262, XP055532384

DOI:   http://dx.doi.org/10.1016/j.celrep.2016.12.019
    - MARABELLE A. et al., "Association of tumour mutational burden with outcomes in patients with advanced solid tumours treated with pembrolizumab: prospective biomarker analysis of the multicohort, open-label, phase 2 KEYNOTE-158 study", Lancet Oncol., (20200000), vol. 21, no. 10, doi:10.1016/S1470-2045(20)30445-9, pages 1353 - 1365, XP086271665

DOI:   http://dx.doi.org/10.1016/S1470-2045(20)30445-9
    - PARE L. et al., "Association between PD1 mRNA and response to anti-PD1 monotherapy across multiple cancer types", Ann Oncol., (20180000), vol. 29, no. 10, pages 2121 - 2128
    - SHITARA K et al., "Efficacy and Safety of Pembrolizumab or Pembrolizumab Plus Chemotherapy vs Chemotherapy Alone for Patients With First-line, Advanced Gastric Cancer: The KEYNOTE-062 Phase 3 Randomized Clinical Trial", JAMA Oncol, (20201001), vol. 6, no. 10, pages 1571 - 1580
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