blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP4158352

EP4158352 - METHOD AND KIT FOR THE EARLY DETECTION OF SEPSIS [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  03.03.2023
Database last updated on 07.10.2024
FormerThe international publication has been made
Status updated on  10.12.2021
Formerunknown
Status updated on  02.06.2021
Most recent event   Tooltip27.04.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Loop Diagnostics, S.L.
Santa Maria, 4 - 5
42001 Soria / ES
For all designated states
Fundació Institut d'Investigació Biomèdica de Bellvitge (IDIBELL)
Hospital Duran i Reynals
2ª planta, Av. Gran Via, 199-203
08908 Hospitalet de Llobregat, Barcelona / ES
[2023/14]
Inventor(s)01 / HERNÁNDEZ JIMÉNEZ, Enrique
08028 Barcelona / ES
02 / JANSEN, Raoul
6336 XV Hulsberg / NL
03 / SABATER RIERA, Joan
08908 L'Hospitalet de Llobregat, Barcelona / ES
 [2023/14]
Representative(s)ABG Intellectual Property Law, S.L.
Avenida de Burgos, 16D
Edificio Euromor
28036 Madrid / ES
[2023/14]
Application number, filing date21727499.231.05.2021
[2023/14]
WO2021EP64544
Priority number, dateEP2020038246201.06.2020         Original published format: EP 20382462
[2023/14]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021245025
Date:09.12.2021
Language:EN
[2021/49]
Type: A1 Application with search report 
No.:EP4158352
Date:05.04.2023
Language:EN
The application published by WIPO in one of the EPO official languages on 09.12.2021 takes the place of the publication of the European patent application.
[2023/14]
Search report(s)International search report - published on:EP09.12.2021
ClassificationIPC:G01N33/68
[2023/14]
CPC:
G01N33/6893 (EP,US); G01N33/6869 (US); G01N2333/52 (EP,US);
G01N2400/50 (EP,US); G01N2800/26 (EP,US); G01N2800/382 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/14]
TitleGerman:VERFAHREN UND KIT ZUM FRÜHEN NACHWEIS VON SEPSIS[2023/14]
English:METHOD AND KIT FOR THE EARLY DETECTION OF SEPSIS[2023/14]
French:MÉTHODE ET TROUSSE DE DÉTECTION PRÉCOCE DE SEPTICÉMIE[2023/14]
Entry into regional phase16.12.2022National basic fee paid 
16.12.2022Designation fee(s) paid 
16.12.2022Examination fee paid 
Examination procedure16.12.2022Examination requested  [2023/14]
16.12.2022Date on which the examining division has become responsible
19.07.2023Amendment by applicant (claims and/or description)
Fees paidRenewal fee
11.05.2023Renewal fee patent year 03
25.04.2024Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[A]US5262296  (OGAWA ETSUKO [JP], et al) [A] 14 * claim 6 *;
 [Y]US2004106142  (IVEY RICHARD M [US], et al) [Y] 7,8,10 * [0066];; table 1 *;
 [A]  - HARRY MOSCOVITZ ET AL, "Plasma cytokine determinations in emergency department patients as a predictor of bacteremi and infectious disease severity :", CRITICAL CARE MEDICINE., US, (19940701), vol. 22, no. 7, doi:10.1097/00003246-199407000-00009, ISSN 0090-3493, pages 1102 - 1107, XP055747031 [A] 1-7,10 * abstract *

DOI:   http://dx.doi.org/10.1097/00003246-199407000-00009
 [A]  - TRAVIS L. HOLLOWAY ET AL, "Toll-like receptor responses are suppressed in trauma ICU patients", JOURNAL OF SURGICAL RESEARCH., US, (20161101), vol. 206, no. 1, doi:10.1016/j.jss.2016.06.056, ISSN 0022-4804, pages 139 - 145, XP055748273 [A] 14 * (p 141, col 1, para 2) *

DOI:   http://dx.doi.org/10.1016/j.jss.2016.06.056
 [A]  - MILENA KARINA COLÓ BRUNIALTI ET AL, "Influence of EDTA and heparin on lipopolysaccharide binding and cell activation, evaluated at single-cell level in whole blood : LPS Interaction and Cell Activation in WB", CYTOMETRY, US, (20020215), vol. 50, no. 1, doi:10.1002/cyto.10049, ISSN 0196-4763, pages 14 - 18, XP055748274 [A] 14 * (p 15, col 1, para 3) *

DOI:   http://dx.doi.org/10.1002/cyto.10049
 [A]  - SZODORAY P ET AL, "CORCULATING CYTOKINES IN PRIMARY SJOGREN'S SYNDROME DETERMINED BY A MULTIPLEX CYTOKINE ARRAY SYSTEM", SCANDINAVIAN JOURNAL OF IMMUNOLOGY, BLACKWELL SCIENCE PUBL., OXFORD, GB, (20040601), vol. 59, no. 6, doi:10.1111/J.0300-9475.2004.01432.X, ISSN 0300-9475, pages 592 - 599, XP001204356 [A] 14 * (p 593, col 2, para 1) *

DOI:   http://dx.doi.org/10.1111/j.0300-9475.2004.01432.x
 [Y]  - JESSICA Z. KUBICEK-SUTHERLAND ET AL, "Direct detection of bacteremia by exploiting host-pathogen interactions of lipoteichoic acid and lipopolysaccharide", SCIENTIFIC REPORTS, (20190417), vol. 9, no. 1, doi:10.1038/s41598-019-42502-5, XP055748276 [Y] 1-25,28-44 * abstract *

DOI:   http://dx.doi.org/10.1038/s41598-019-42502-5
 [Y]  - KATHRYN E HALLY ET AL, "Platelets regulate leucocyte responses to Toll-like receptor stimulation", CLINICAL & TRANSLATIONAL IMMUNOLOGY, GB, (20180101), vol. 7, no. 7, doi:10.1002/cti2.1036, ISSN 2050-0068, page e1036, XP055746116 [Y] 1-25,28-44 * abstract *

DOI:   http://dx.doi.org/10.1002/cti2.1036
 [Y]  - SALOMAO REINALDO ET AL, "Lipopolysaccharide-cell interaction and induced cellular activation in whole blood of septic patients", JOURNAL OF ENDOTOXIN RESEARCH, UK, (20021001), vol. 8, no. 5, doi:10.1179/096805102125000704, ISSN 0968-0519, pages 371 - 379, XP055829747 [Y] 1-25,28-44 * (p 372, col 2, first lines)(p 377, col 2, last para);; figure 4 *

DOI:   http://dx.doi.org/10.1179/096805102125000704
 [Y]  - GUADALUPE MARTIN ET AL, "Role of plasma matrix-metalloproteases (MMPs) and their polymorphisms (SNPs) in sepsis development and outcome in ICU patients", SCIENTIFIC REPORTS, (20140516), vol. 4, no. 1, doi:10.1038/srep05002, XP055748226 [Y] 7,10 * abstract *

DOI:   http://dx.doi.org/10.1038/srep05002
 [Y]  - PING ZHANG ET AL, "The Lineage-c-Kit+Sca-1+ Cell Response to Escherichia coli Bacteremia in Balb/c Mice", STEM CELLS (MIAMISBURG), (20080701), vol. 26, no. 7, doi:10.1634/stemcells.2007-1027, ISSN 1066-5099, pages 1778 - 1786, XP055748277 [Y] 7,10 * page 1183 *

DOI:   http://dx.doi.org/10.1634/stemcells.2007-1027
 [Y]  - SANNE VAN DEN BERG ET AL, "Distinctive Cytokines as Biomarkers Predicting Fatal Outcome of Severe Staphylococcus aureus Bacteremia in Mice", PLOS ONE, (20130301), vol. 8, no. 3, doi:10.1371/journal.pone.0059107, page e59107, XP055748178 [Y] 7,10 * p 3, col 1, para 1 *

DOI:   http://dx.doi.org/10.1371/journal.pone.0059107
 [Y]  - CHIA-TE KUNG ET AL, "Serum adhesion molecules as predictors of bacteremia in adult severe sepsis patients at the emergency department", CLINICA CHIMICA ACTA, AMSTERDAM, NL, (20130601), vol. 421, doi:10.1016/j.cca.2013.02.023, ISSN 0009-8981, pages 116 - 120, XP055748235 [Y] 7,10 * abstract *

DOI:   http://dx.doi.org/10.1016/j.cca.2013.02.023
 [Y]  - DANFENG XU ET AL, "Brain-derived neurotrophic factor is regulated via MyD88/NF-[kappa]B signaling in experimental Streptococcus pneumoniae meningitis", SCIENTIFIC REPORTS, (20170614), vol. 7, no. 1, doi:10.1038/s41598-017-03861-z, XP055748241 [Y] 7,10 * abstract *

DOI:   http://dx.doi.org/10.1038/s41598-017-03861-z
 [Y]  - CHEN JINWU ET AL, "Coagulation factors VII, IX and X are effective antibacterial proteins against drug-resistant Gram-negative bacteria", CELL RESEARCH, NATURE PUBLISHING GROUP, GB, CN, vol. 29, no. 9, doi:10.1038/S41422-019-0202-3, ISSN 1001-0602, (20190809), pages 711 - 724, (20190809), XP036875198 [Y] 7,10 * abstract *

DOI:   http://dx.doi.org/10.1038/s41422-019-0202-3
 [Y]  - BOSMANN M ET AL, "Therapeutic potential of targeting IL-17 and IL-23 in sepsis", CLINICAL AND TRANSLATIONAL MEDICINE, INTERNATIONAL SOCIETY FOR TRANSLATIONAL MEDICINE, SE, (20120427), vol. 1, no. 1, doi:10.1186/2001-1326-1-4, ISSN 2001-1326, pages 4 - 1, XP002717294 [Y] 7,10 * abstract *

DOI:   http://dx.doi.org/10.1186/2001-1326-1-4
by applicantUS347
 US6303
 US4436727
 US4477575
 US4866034
 US4877611
 US4912094
 US5166051
 US5480792
 US5525524
 US5631171
 US5679526
 US5824799
 WO9850399
 US5851776
 US5885527
 US5922615
 US5939272
 US5947124
 US5955377
 US5985579
 US6019944
 US6113855
 US6143576
 US6391265
 WO03011223
 WO03099195
 US6764840
 US7125493
    - DELLINGER et al., Intensive Care Med, (20130000), vol. 39, pages 165 - 228
    - COBURN et al., JAMA, (20120000), vol. 308, pages 502 - 511
    - TANG et al., Lancet Infect Dis, (20070000), vol. 7, pages 210 - 217
    - UZZAN et al., Crit Care Med, (20060000), vol. 34, pages 1996 - 2003
    - CHEVAL et al., Intensive Care Med, (20000000), vol. 26, pages 153 - 158
    - UGARTE et al., Crit Care Med, (19990000), vol. 27, pages 498 - 504
    - VEGA et al., Crit Care Med, (20090000), vol. 37, pages 1806 - 1807
    - KIRCHHOFER et al., Arterioscler. Thromb. Vase. Biol., (19950000), vol. 15, pages 1098 - 1106
    - KIRCHHOFER et al., J. Clin. Invest., (19940000), vol. 93, pages 2073 - 83
    - SABROE et al., JI, (20030000), pages 1630 - 5
    - "Swiss-Prot", Database accession no. 000206
    - FENG Y et al., Nat Commun, (20190522), vol. 10, no. 1, page 2272
    - "database", Database accession no. ENSG00000226979
    - JAYESH M. BHATT, European Respiratory Review, (20130000), vol. 22, pages 205 - 2016
    - WATERS VRATJEN F, Ann Am Thorac Soc, (20151100), vol. 12, pages 200 - 6
    - FUCHS et al., N Engl J Med., (19940908), vol. 331, no. 10, pages 637 - 42
    - TREGGIARI et al., Contemp Clin Trials, (20090000), vol. 30, pages 256 - 268
    - FISCHER, Intensive Care Med, (20030000), vol. 29, pages 1043 - 51
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.