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Extract from the Register of European Patents

EP About this file: EP4210742

EP4210742 - BISPECIFIC ANTIBODY AGAINST CD3 AND CD20 IN COMBINATION THERAPY FOR TREATING FOLLICULAR LYMPHOMA [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  16.06.2023
Database last updated on 17.09.2024
FormerThe international publication has been made
Status updated on  23.03.2022
Formerunknown
Status updated on  07.10.2021
Most recent event   Tooltip03.11.2023Amendment by applicant 
Applicant(s)For all designated states
Genmab A/S
Carl Jacobsens Vej 30
2500 Valby / DK
[2023/42]
Former [2023/29]For all designated states
Genmab A/S
Kalvebod Brygge 43
1560 Copenhagen V / DK
Inventor(s)01 / ELLIOTT, Brian
Plainsboro, New Jersey 08536 / US
02 / AHMADI, Tahamtan
Plainsboro, New Jersey 08536 / US
03 / CHIU, Christopher
Plainsboro, New Jersey 08536 / US
04 / BREIJ, Esther C. W.
3584 CT Utrecht / NL
05 / HIEMSTRA, Ida
3584 CT Utrecht / NL
06 / JURE-KUNKEL, Maria N.
Plainsboro, New Jersey 08536 / US
 [2023/29]
Representative(s)Genmab A/S
Carl Jacobsens Vej 30
2500 Valby / DK
[N/P]
Application number, filing date21777653.310.09.2021
[2023/29]
WO2021EP75017
Priority number, dateUS202063076740P10.09.2020         Original published format: US 202063076740 P
[2023/29]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2022053655
Date:17.03.2022
Language:EN
[2022/11]
Type: A1 Application with search report 
No.:EP4210742
Date:19.07.2023
Language:EN
The application published by WIPO in one of the EPO official languages on 17.03.2022 takes the place of the publication of the European patent application.
[2023/29]
Search report(s)International search report - published on:EP17.03.2022
ClassificationIPC:A61K39/395, A61P35/02, C07K16/28, A61K39/00
[2023/29]
CPC:
C07K16/2887 (EP,IL,KR,US); A61K39/395 (EP,IL,KR); A61K31/454 (IL,KR,US);
A61P35/00 (US); A61P35/02 (EP,IL,KR); C07K16/2809 (EP,IL,KR,US);
C07K16/468 (US); A61K2039/507 (EP,IL,KR); A61K2039/545 (KR);
A61K2300/00 (KR); C07K2317/24 (IL,US); C07K2317/31 (EP,IL,KR,US);
C07K2317/52 (IL,US); C07K2317/565 (EP,IL,KR,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/29]
Extension statesBA04.04.2023
ME04.04.2023
Validation statesKH04.04.2023
MA04.04.2023
MD04.04.2023
TN04.04.2023
TitleGerman:BISPEZIFISCHER ANTIKÖRPER GEGEN CD3 UND CD20 IN EINER KOMBINATIONSTHERAPIE ZUR BEHANDLUNG VON FOLLIKELLYMPHOM[2023/29]
English:BISPECIFIC ANTIBODY AGAINST CD3 AND CD20 IN COMBINATION THERAPY FOR TREATING FOLLICULAR LYMPHOMA[2023/29]
French:ANTICORPS BISPÉCIFIQUE CONTRE CD3 ET CD20 EN POLYTHÉRAPIE POUR LE TRAITEMENT D'UN LYMPHOME FOLLICULAIRE[2023/29]
Entry into regional phase04.04.2023National basic fee paid 
04.04.2023Designation fee(s) paid 
04.04.2023Examination fee paid 
Examination procedure04.04.2023Examination requested  [2023/29]
04.04.2023Date on which the examining division has become responsible
01.11.2023Amendment by applicant (claims and/or description)
Fees paidRenewal fee
24.08.2023Renewal fee patent year 03
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Cited inInternational search[A]WO2016110576  (GENMAB AS [DK]) [A] 1-48* the whole document *;
 [A]  - MORSCHHAUSER FRANCK ET AL, "Rituximab plus Lenalidomide in Advanced Untreated Follicular Lymphoma", THE NEW ENGLAND JOURNAL OF MEDICINE, US, (20180906), vol. 379, no. 10, doi:10.1056/NEJMoa1805104, ISSN 0028-4793, pages 934 - 947, XP055855089 [A] 1-48 * the whole document *

DOI:   http://dx.doi.org/10.1056/NEJMoa1805104
 [AD]  - PATRICK J. ENGELBERTS ET AL, "DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing", EBIOMEDICINE, NL, (20200201), vol. 52, doi:10.1016/j.ebiom.2019.102625, ISSN 2352-3964, page 102625, XP055762370 [AD] 1-48 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.ebiom.2019.102625
 [AD]  - VAN DER HORST HILMA J ET AL, "Duobody-CD3xCD20 Induces Potent Anti-Tumor Activity in Malignant Lymph Node B Cells from Patients with DLBCL, FL and MCL Ex Vivo, Irrespective of Prior Treatment with CD20 Monoclonal Antibodies", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, (20191113), vol. 134, doi:10.1182/BLOOD-2019-125765, ISSN 0006-4971, page 4066, XP086675260 [AD] 1-48 * the whole document *

DOI:   http://dx.doi.org/10.1182/blood-2019-125765
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 WO2009089004
 WO2010129304
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 WO2013060867
 WO2015001085
 WO2016110576
 WO2019155008
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 US20100155133
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