Extract from the Register of European Patents

EP About this file: EP4127152

EP4127152 - METHODS, COMPOSITIONS, AND KITS FOR IDENTIFYING REGIONS OF GENOMIC DNA BOUND TO A PROTEIN [Right-click to bookmark this link]
StatusGrant of patent is intended
Status updated on  11.03.2026
Database last updated on 11.04.2026
FormerExamination is in progress
Status updated on  28.02.2026
FormerGrant of patent is intended
Status updated on  02.11.2025
FormerExamination is in progress
Status updated on  18.04.2025
FormerRequest for examination was made
Status updated on  06.01.2023
FormerThe international publication has been made
Status updated on  09.10.2021
Most recent event   Tooltip07.04.2026New entry: Renewal fee paid 
Applicant(s)For all designated states
Altius Institute For Biomedical Sciences
2211 Elliott Avenue, 4th Floor
Seattle, WA 98121 / US
For all designated states
The Brigham & Women's Hospital, Inc.
75 Francis Street
Boston, Massachusetts 02115 / US
[2023/06]
Inventor(s)01 / STAMATOYANNOPOULOS, John A.
2211 Elliott Avenue, 4th Floor
Seattle, Washington 98121 / US
02 / STERGACHIS, Andrew B.
75 Francis St.
Boston, Massachusetts 02115 / US
 [2023/06]
Representative(s)Boult Wade Tennant LLP
Salisbury Square House
8 Salisbury Square
London EC4Y 8AP / GB
[2023/06]
Application number, filing date21780901.102.04.2021
[2023/06]
WO2021US25644
Priority number, dateUS202063004361P02.04.2020         Original published format: US 202063004361 P
[2023/06]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021203047
Date:07.10.2021
Language:EN
[2021/40]
Type: A1 Application with search report 
No.:EP4127152
Date:08.02.2023
Language:EN
The application published by WIPO in one of the EPO official languages on 07.10.2021 takes the place of the publication of the European patent application.
[2023/06]
Search report(s)International search report - published on:US07.10.2021
(Supplementary) European search report - dispatched on:EP04.04.2024
ClassificationIPC:C12Q1/6806, C12N9/10, C12N9/22, C12N15/09, C12Q1/68, C40B30/00, C40B30/04, G01N1/28, C12Q1/6869
[2024/18]
CPC:
C12N9/1007 (EP,US); C12Q1/6806 (EP,US); C12Q1/6869 (EP,US);
C12Y201/01072 (EP,US)
C-Set:
C12Q1/6806, C12Q2521/125, C12Q2522/10, C12Q2535/122, C12Q2537/164, C12Q2565/631 (EP);
C12Q1/6806, C12Q2521/125, C12Q2535/122 (EP);
C12Q1/6869, C12Q2521/125, C12Q2522/10, C12Q2535/122, C12Q2537/164, C12Q2565/631 (EP)
Former IPC [2023/06]C12N9/10, C12N9/22, C12N15/09, C12Q1/68, C40B30/00, C40B30/04, G01N1/28
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/06]
TitleGerman:VERFAHREN, ZUSAMMENSETZUNGEN UND KITS ZUR IDENTIFIZIERUNG VON REGIONEN GENOMISCHER DNA, DIE AN EIN PROTEIN GEBUNDEN IST[2023/06]
English:METHODS, COMPOSITIONS, AND KITS FOR IDENTIFYING REGIONS OF GENOMIC DNA BOUND TO A PROTEIN[2023/06]
French:PROCÉDÉS, COMPOSITIONS ET KITS POUR IDENTIFIER DES RÉGIONS D'ADN GÉNOMIQUE LIÉES À UNE PROTÉINE[2023/06]
Entry into regional phase26.10.2022National basic fee paid 
26.10.2022Search fee paid 
26.10.2022Designation fee(s) paid 
26.10.2022Examination fee paid 
Examination procedure26.10.2022Examination requested  [2023/06]
22.10.2024Amendment by applicant (claims and/or description)
22.10.2024Date on which the examining division has become responsible
24.04.2025Despatch of a communication from the examining division (Time limit: M04)
13.08.2025Reply to a communication from the examining division
03.11.2025Communication of intention to grant the patent
25.02.2026Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
11.03.2026Communication of intention to grant the patent
Fees paidRenewal fee
14.03.2023Renewal fee patent year 03
13.03.2024Renewal fee patent year 04
13.03.2025Renewal fee patent year 05
06.04.2026Renewal fee patent year 06
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Documents cited:Search[E]   SHIPONY ZOHAR ET AL: "Long-range single-molecule mapping of chromatin accessibility in eukaryotes", NATURE METHODS, NATURE PUBLISHING GROUP US, NEW YORK, vol. 17, no. 3, 10 February 2020 (2020-02-10), pages 319 - 327, XP037050146, ISSN: 1548-7091, [retrieved on 20200210], DOI: 10.1038/S41592-019-0730-2

DOI:   http://dx.doi.org/10.1038/s41592-019-0730-2
 [Y]   RHOADS ANTHONY ET AL: "PacBio Sequencing and Its Applications", GENOMICS PROTEOMICS AND BIOINFORMATICS, BEIJING GENOMICS INSTITUTE, BEIJING, CN, vol. 13, no. 5, 2 November 2015 (2015-11-02), pages 278 - 289, XP029335898, ISSN: 1672-0229, DOI: 10.1016/J.GPB.2015.08.002

DOI:   http://dx.doi.org/10.1016/j.gpb.2015.08.002
 [A]   WENGER AARON M ET AL: "Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP US, NEW YORK, vol. 37, no. 10, 12 August 2019 (2019-08-12), pages 1155 - 1162, XP036897227, ISSN: 1087-0156, [retrieved on 20190812], DOI: 10.1038/S41587-019-0217-9

DOI:   http://dx.doi.org/10.1038/s41587-019-0217-9
International search[XY] US2010221716  (FLUSBERG BENJAMIN et al.) [X] 1, 2, 7, 8, 54-57 * entire document *[Y] 3-6, 9, 10, 58
 [XY] WO2018227025  (ARC BIO LLC et al.) [X] 41,42, 44, 47, 48, 50 * entire document *[Y] 43, 45, 46, 49
 [Y] US2017369855  (NOVINA CARL et al.) [Y] 9, 10, 49 * entire document *
 [Y] US6413751  (BENKOVIC STEPHEN J et al.) [Y] 58 * entire document *
 [A] US2012115132  (COPENHAVER GREGORY P et al.) [A] 1-10, 41-50, 54-58 * entire document *
 [A] WO2019139951  (THE US SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES et al.) [A] 1-10, 41-50, 54-58 * entire document *
 [A] US2018265922  (WEITZ DAVID A et al.) [A] 1-10, 41-50, 54-58 * entire document *
 [Y]   ANTON BRIAN P., HARHAY GREGORY P., SMITH TIMOTHY P. L., BLOM JOCHEN, ROBERTS RICHARD J.: "Comparative Methylome Analysis of the Occasional Ruminant Respiratory Pathogen Bibersteinia trehalosi", PLOS ONE, PUBLIC LIBRARY OF SCIENCE, vol. 11, no. 8, 24 August 2016 (2016-08-24), pages e0161499, XP055925794, DOI: 10.1371/journal.pone.0161499 [Y] 3, 5, 43, 45 * . entire document *

DOI:   http://dx.doi.org/10.1371/journal.pone.0161499
 [Y]   MURRAY IAIN A, MORGAN RICHARD D, LUYTEN YVETTE, FOMENKOV ALEXEY, CORRA IVAN R., DAI NAN, ALLAW MOHAMMED B, ZHANG XING, CHENG XIAO: "The non-specific adenine DNA methyltransferase M.EcoGII", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, GB, vol. 46, no. 2, 25 January 2018 (2018-01-25), GB , pages 840 - 848, XP055925795, ISSN: 0305-1048, DOI: 10.1093/nar/gkx1191 [Y] 4, 6, 46 * . entire document *

DOI:   http://dx.doi.org/10.1093/nar/gkx1191
by applicant  SHIPONY, Z. ET AL., NATURE METHODS, vol. 17, no. 3, 2020, pages 319 - 327 [Y] 3-6, 9, 10, 58
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