Extract from the Register of European Patents

EP About this file: EP4130274

EP4130274 - METHOD FOR EDITING TARGET RNA [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  06.01.2023
Database last updated on 28.03.2026
FormerThe international publication has been made
Status updated on  08.06.2022
Most recent event   Tooltip21.03.2026New entry: Renewal fee paid 
Applicant(s)For all designated states
EditForce, Inc.
1-9-17, Tenjin, Chuo-ku
Fukuoka-shi, Fukuoka 810-0001 / JP
[N/P]
Former [2023/06]For all designated states
Editforce, Inc.
1-9-17, Tenjin, Chuo-ku
Fukuoka-shi, Fukuoka, 810-0001 / JP
Inventor(s)01 / ICHINOSE, Mizuho
c/o NATIONAL UNIVERSITY CORPORATION TOKAI
NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM
1, Furo-cho, Chikusa-ku
Nagoya-shi, Aichi 464-8601 / JP
02 / GUTMANN, Bernard
c/o EditForce, Inc.
1-9-17, Tenjin, Chuo-ku
Fukuoka-shi, Fukuoka 810-0001 / JP
03 / YAGI, Yusuke
c/o EditForce, Inc.
1-9-17, Tenjin, Chuo-ku
Fukuoka-shi, Fukuoka 810-0001 / JP
04 / AKAIWA, Yumi
c/o EditForce, Inc.
1-9-17, Tenjin, Chuo-ku
Fukuoka-shi, Fukuoka 810-0001 / JP
05 / SHIMAJIRI, Yasuka
c/o EditForce, Inc.
1-9-17, Tenjin, Chuo-ku
Fukuoka-shi, Fukuoka 810-0001 / JP
06 / NAKAMURA, Takahiro
c/o KYUSHU UNIVERSITY,
NATIONAL UNIVERSITY CORPORATION
744, Motooka, Nishi-ku
Fukuoka-shi, Fukuoka 819-0395 / JP
 [2023/06]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[2023/06]
Application number, filing date21781411.031.03.2021
[2023/06]
WO2021JP14096
Priority number, dateJP2020006506531.03.2020         Original published format: JP 2020065065
[2023/06]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021201198
Date:07.10.2021
Language:JA
[2021/40]
Type: A1 Application with search report 
No.:EP4130274
Date:08.02.2023
Language:EN
[2023/06]
Search report(s)International search report - published on:JP07.10.2021
(Supplementary) European search report - dispatched on:EP19.04.2024
ClassificationIPC:C12N15/52, C07K14/415, C12N1/15, C12N1/19, C12N1/21, C12N5/10, C12N15/29
[2023/06]
CPC:
C07K14/415 (EP,IL,KR,US); C12N15/79 (KR); C12N5/10 (IL,US);
C12N15/102 (EP,KR); C12N15/52 (EP,IL); C12N15/70 (EP);
C12N15/74 (IL); C12N15/80 (IL); C12N15/81 (IL);
A61K48/005 (EP); C12N2510/00 (EP,KR) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/06]
TitleGerman:VERFAHREN ZUR BEARBEITUNG VON ZIEL-RNA[2023/06]
English:METHOD FOR EDITING TARGET RNA[2023/06]
French:PROCÉDÉ D'ÉDITION D'ARN CIBLE[2023/06]
Entry into regional phase20.10.2022Translation filed 
20.10.2022National basic fee paid 
20.10.2022Search fee paid 
20.10.2022Designation fee(s) paid 
20.10.2022Examination fee paid 
Examination procedure20.10.2022Examination requested  [2023/06]
08.11.2024Amendment by applicant (claims and/or description)
08.11.2024Date on which the examining division has become responsible
Fees paidRenewal fee
27.02.2023Renewal fee patent year 03
15.02.2024Renewal fee patent year 04
14.02.2025Renewal fee patent year 05
20.03.2026Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[Y]   GERKE PHILIPP ET AL: "Towards a plant model for enigmatic U-to-C RNA editing: the organelle genomes, transcriptomes, editomes and candidate RNA editing factors in the hornwort Anthoceros agrestis", NEW PHYTOLOGIST, vol. 225, no. 5, 14 December 2019 (2019-12-14), GB, pages 1974 - 1992, XP093073777, ISSN: 0028-646X, Retrieved from the Internet DOI: 10.1111/nph.16297 [Y] 1-10 * the whole document *

DOI:   http://dx.doi.org/10.1111/nph.16297
 [Y]   GUTMANN BERNARD ET AL: "The Expansion and Diversification of Pentatricopeptide Repeat RNA-Editing Factors in Plants", MOLECULAR PLANT, vol. 13, no. 2, 1 February 2020 (2020-02-01), pages 215 - 230, XP093146879, ISSN: 1674-2052, Retrieved from the Internet DOI: 10.1016/j.molp.2019.11.002 [Y] 1-10 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.molp.2019.11.002
 [T]   ICHINOSE MIZUHO ET AL: "U-to-C RNA editing by synthetic PPR-DYW proteins in bacteria and human culture cells", COMMUNICATIONS BIOLOGY, vol. 5, no. 1, 15 September 2022 (2022-09-15), XP093146870, ISSN: 2399-3642, Retrieved from the Internet DOI: 10.1038/s42003-022-03927-3 [T]

DOI:   http://dx.doi.org/10.1038/s42003-022-03927-3
 [T]   ROYAN SANTANA ET AL: "A synthetic RNA editing factor edits its target site in chloroplasts and bacteria", COMMUNICATIONS BIOLOGY, vol. 4, no. 1, 10 May 2021 (2021-05-10), XP093146873, ISSN: 2399-3642, Retrieved from the Internet DOI: 10.1038/s42003-021-02062-9 [T]

DOI:   http://dx.doi.org/10.1038/s42003-021-02062-9
International search[XY]   DATABASE Protein 25 July 2016 (2016-07-25), ANONYMOUS : "hypothetical protein SELMODRAFT_107192 [Selaginella moellendorffii]", XP055915656, retrieved from NCBI Database accession no. EFJ21522 [X] 2-4, 8-10 [Y] 1, 7
 [XY]   DATABASE Nucleotide 26 July 2016 (2016-07-26), ANONYMOUS : "Megaceros tosanus clone 1 pentatricopeptide repeat protein (PPR) gene, partial cds", XP055915666, retrieved from NCBI Database accession no. EU495537 [X] 2-4, 8-10 [Y] 1, 5-7
 [Y]   OLDENKOTT BASTIAN, YANG YINGYING, LESCH ELENA, KNOOP VOLKER, SCHALLENBERG-RDINGER MAREIKE: "Plant-type pentatricopeptide repeat proteins with a DYW domain drive C-to-U RNA editing in Escherichia coli", COMMUNICATIONS BIOLOGY, vol. 2, no. 1, 1 December 2019 (2019-12-01), pages 1 - 8, XP055915676, DOI: 10.1038/s42003-019-0328-3 [Y] 1, 5-7

DOI:   http://dx.doi.org/10.1038/s42003-019-0328-3
by applicantWO2013058404
 WO2014175284
   LURIN, C.ANDRES, C.AUBOURG, S.BELLAOUI, M.BITTON, F.BRUYERE, C.CABOCHE, M.DEBAST, C.GUALBERTO, J.HOFFMANN, B. ET AL.: "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins reveals their essential role in organelle biogenesis", PLANT CELL, vol. 16, 2004, pages 2089 - 2103, XP055219280, DOI: 10.1105/tpc.104.022236 [Y] 1, 5-7

DOI:   http://dx.doi.org/10.1105/tpc.104.022236
   CHENG, S.GUTMANN, B.ZHONG, X.YE, Y.FISHER, M. F.BAI, F.CASTLEDEN, ISONG, Y.SONG, B.HUANG, J. ET AL.: "Redefining the structural motifs that determine RNA binding and RNA editing by pentatricopeptide repeat proteins in land plants", PLANT J., vol. 85, 2016, pages 532 - 547
   BARKAN, A.ROJAS, M.FUJII, S.YAP, ACHONG, Y. SBOND, C. S.SMALL, I.: "A combinatorial amino acid code for RNA recognition by pentatricopeptide repeat proteins", PLOS GENET, vol. 8, 2012, pages el 002910
   SHEN, C.ZHANG, DGUAN, ZLIU, YYANG, ZYANG, Y.WANG, X.WANG, QZHANG, Q.FAN, S. ET AL., NAT. COMMUN., vol. 7, 2016, pages 11285
   YAGI, Y.HAYASHI, S.KOBAYASHI, KHIRAYAMA, T.NAKAMURA, T.: "Elucidation of the RNA recognition code for pentatricopeptide repeat proteins involved in organelle RNA editing in plants", PLOS ONE, vol. 8, 2013, pages e57286
   KOBAYASHI, T.YAGI, Y.NAKAMURA, T.: "Comprehensive Prediction of Target RNA Editing Sites for PLS-Class PPR Proteins in Arabidopsis thaliana", PLANT CELL PHYSIOL., vol. 60, 2019, pages 862 - 874
   YAN, J.YAO, YHONG, SYANG, Y.SHEN, C.ZHANG, QZHANG, D.ZOU, T.YIN, P.: "Delineation of pentatricopeptide repeat codes for target RNA prediction", NUCLEIC ACIDS RES., vol. 47, 2019, pages 3728 - 3738, XP055769935, DOI: 10.1093/nar/gkz075

DOI:   http://dx.doi.org/10.1093/nar/gkz075
   TAKENAKA, M., ZEHRMANN, A., BRENNICKE, A., AND GRAICHEN, K.: "Improved computational target site prediction for pentatricopeptide repeat RNA editing factors", PLOS ONE, vol. 8, 2013, pages e65343
   KNIE, N.GREWE, F.FISCHER, S.KNOOP, V.: "Reverse U-to-C editing exceeds C-to-U RNA editing in some ferns - a monilophyte-wide comparison of chloroplast and mitochondrial RNA editing suggests independent evolution of the two processes in both organelles", BMC EVOL. BIOL., vol. 16, 2016, pages 134
   GERKE, P.SZOVENYI, PNEUBAUER, ALENZ, HGUTMANN, B.MCDOWELL, R.SMALL, I.SCHALLENBERG-RUDINGER, M.KNOOP, V.: "Towards a plant model for enigmatic U-to-C RNA editing: the organelle genomes, transcriptomes, editomes and candidate RNA editing factors in the homwort Anthoceros agrestis", NEW PHYTOLOGIST, vol. 225, 2020, pages 1974 - 1992
   GUTMANN B.ROYAN S.SCHALLENBERG-RUDINGER M.LENZ H.CASTLEDEN I.R.MCDOWELL R.VACHER M.A.TONTI-FILIPPINI JBOND C.SKNOOP V: "The Expansion and Diversification of Pentatricopeptide Repeat RNA-Editing Factors in Plants", MOLECULAR PLANT, vol. 13, 2020, pages 215 - 230
   OLDENKOTT, BYANG, YLESCH, EKNOOP, V.SCHALLENBERG-RUDINGER, M: "Plant-type pentatricopeptide repeat proteins with a DYW domain drive C-to-U RNA editing in Escherichia coli", COMMUNICATIONS BIOLOGY, vol. 2, 2019, pages 85, XP055915676, DOI: 10.1038/s42003-019-0328-3

DOI:   http://dx.doi.org/10.1038/s42003-019-0328-3
   LETUNIC, 1BORK, P, NUCLEIC ACIDS RES., vol. 44, 2016, pages W242 - 245
   CHATEIGNER-BOUTIN, A.L. ET AL., PLANT J., vol. 56, 2008, pages 590 - 602
   LARSSON, A.: "AliView: a fast and lightweight alignment viewer and editor for large data sets", BIOINFONNATICS, vol. 30, no. 22, 2014, pages 3276 - 3278, Retrieved from the Internet
   RUWE ET AL., NEW PHYTOL., vol. 222, 2019, pages 218 - 229
   NUCLEIC ACIDS RESEARCH, vol. 40, no. 6, 2012, pages 2712 - 2723
   ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 410
   K. KATOHD.M. STANDLEY, MOL. BIOL. EVOL., vol. 30, no. 4, 2013, pages 772 - 780
   SALVADOR CAPELLA-GUTIERREZ, BIOINFORMATICS, vol. 25, no. 15, 2009, pages 1972 - 1973
   PRICE, M. N. ET AL., PLOS ONE, vol. 5, 2010, pages e9490
   ABUDAYYEH ET AL., SCIENCE, vol. 365, 2019, pages 382 - 386
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.