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Extract from the Register of European Patents

EP About this file: EP4155294

EP4155294 - COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  24.02.2023
Database last updated on 03.10.2024
FormerThe international publication has been made
Status updated on  29.10.2021
Most recent event   Tooltip16.04.2024Supplementary search reportpublished on 15.05.2024  [2024/20]
Applicant(s)For all designated states
Fudan University
No. 220 Handan Road Yangpu District
Shanghai 200433 / CN
[2023/13]
Inventor(s)01 / LU, Boxun
2005 Songhu Road
Shanghai 200438 / CN
02 / FU, Yuhua
2005 Songhu Road
Shanghai 200438 / CN
03 / DING, Yu
2005 Songhu Road
Shanghai 200438 / CN
 [2023/13]
Representative(s)Reitstötter Kinzebach
Patentanwälte
Sternwartstraße 4
81679 München / DE
[N/P]
Former [2023/13]Reitstötter Kinzebach
Patentanwälte
Sternwartstrasse 4
81679 München / DE
Application number, filing date21793702.823.04.2021
[2023/13]
WO2021CN89453
Priority number, dateCN20201032891123.04.2020         Original published format: CN202010328911
[2023/13]
Filing languageZH
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021213518
Date:28.10.2021
Language:ZH
[2021/43]
Type: A1 Application with search report 
No.:EP4155294
Date:29.03.2023
Language:EN
[2023/13]
Search report(s)International search report - published on:CN28.10.2021
(Supplementary) European search report - dispatched on:EP15.04.2024
ClassificationIPC:C07D209/34, C07D403/06, C07D311/16, C07D239/88, C07D403/12, C07D487/04, C07D401/12, C07D513/04, C07D409/14, C07D239/70, C07J9/00, A61P3/00, A61P3/04, A61P3/10, A61P1/16, A61P35/00, A61P9/10, A61P25/28, A61K31/352, A61K31/404
[2023/13]
CPC:
C07D209/34 (EP,CN); A61K47/545 (EP,US); A61K41/00 (US);
A61K47/54 (EP); A61K47/55 (US); A61K47/554 (EP,US);
A61P1/16 (EP,CN); A61P25/28 (EP,CN); A61P3/00 (EP,CN);
A61P3/04 (EP,CN); A61P3/06 (US); A61P3/10 (EP,CN);
A61P35/00 (EP,CN); A61P9/10 (EP,CN); C07D239/70 (CN);
C07D239/88 (CN); C07D239/90 (EP); C07D311/16 (EP,CN);
C07D401/12 (EP,CN); C07D403/06 (CN); C07D403/12 (CN);
C07D409/14 (CN); C07D417/12 (EP); C07D417/14 (EP);
C07D487/04 (CN); C07D513/04 (CN); C07J9/00 (CN) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/13]
TitleGerman:VERBINDUNG ZUR PRÄVENTION ODER BEHANDLUNG VON ERKRANKUNGEN IM ZUSAMMENHANG MIT DEM LIPIDSTOFFWECHSEL[2023/13]
English:COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES[2023/13]
French:COMPOSÉ POUR LA PRÉVENTION OU LE TRAITEMENT DE MALADIES LIÉES AU MÉTABOLISME LIPIDIQUE[2023/13]
Entry into regional phase17.11.2022Translation filed 
17.11.2022National basic fee paid 
17.11.2022Search fee paid 
17.11.2022Designation fee(s) paid 
17.11.2022Examination fee paid 
Examination procedure17.11.2022Amendment by applicant (claims and/or description)
17.11.2022Examination requested  [2023/13]
Fees paidRenewal fee
30.03.2023Renewal fee patent year 03
27.03.2024Renewal fee patent year 04
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Documents cited:Search[I]US2019290778  (NOMURA DANIEL K [US], et al)
International search[A]CN101106998  (MERCK & CO INC [US]) [A] 1-9, 15-17, 23-27 * entire document *;
 [XA]  - Lang Wenjie, Yuan Chaonan, Zhu Biwei, Pan Sijun, Liu Jian, Luo Jie, Nie Shikun, Zhu Qing, Lee Jun-Seok, Ge Jingyan, "Expanding the “minimalist” small molecule tagging approach to different bioactive compounds", Organic & Biomolecular Chemistry, Royal Society of Chemistry, (20190313), vol. 17, no. 11, doi:10.1039/C8OB03175D, ISSN 1477-0520, pages 3010 - 3017, XP055859536 [X] 1-3, 5, 9, 15, 23 * p. 3012, figure 2 and p. 3010, the abstract * [A] 4, 6-8, 16, 17, 24-27

DOI:   http://dx.doi.org/10.1039/C8OB03175D
 [A]  - Li Zhaoyang; Wang Cen; Wang Ziying; Zhu Chenggang; Li Jie; Sha Tian; Ma Lixiang; Gao Chao; Yang Yi; Sun Yimin; Wang Jian; Sun Xiaoli; Lu Chenqi; Difiglia Marian; Mei Yanai; Ding Chen; Luo Shouqing; Dang Yongjun; Ding Yu; Fei Yiyan; Lu Boxun, "Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds", Nature, Nature Publishing Group UK, London, London, (20191030), vol. 575, no. 7781, doi:10.1038/s41586-019-1722-1, ISSN 0028-0836, pages 203 - 209, XP036932218 [A] 1-9, 15-17, 23-27 * pp. 203-209 *

DOI:   http://dx.doi.org/10.1038/s41586-019-1722-1
 [A]  - Naumov Mikael, Nuchev Alexander, Sitnikov Nikolay, Malysheva Yulia, Shavyrin Andrew, Beletskaya Irina, Gavryushin Andrei, Combes Sebastien, Fedorov Alexey, "2-(Azidomethyl)arylboronic Acids in the Synthesis of Coumarin-Type Compounds", SYNTHESIS, GEORG THIEME VERLAG, STUTTGART, DE., STUTTGART, DE. , (20090501), vol. 2009, no. 10, doi:10.1055/s-0028-1088058, ISSN 0039-7881, pages 1673 - 1682, XP055859538 [A] 1-9, 15-17, 23-27 * pp. 1673-1682 *

DOI:   http://dx.doi.org/10.1055/s-0028-1088058
by applicant   - J. RAUTIO et al., Nature Reviews Drug Discovery, (20080000), vol. 7, pages 255 - 270
    - FAM et al., "Recent Advances in Fluorescent Probes for Lipid Droplets.", Materials, (20180000), vol. 11, page 1768
    - "Uniprot", Database accession no. Q9H492-2
    - MANDAL, "Quantum Dot-Based Designed Nanoprobe for Imaging Lipid Droplet", J. Phys. Chem. C, (20170000), vol. 121, no. 42, pages 23727 - 23735
    - CAS , no. 945595-80-2
    - SOOKOIAN S et al., "Fatty Liver Disease Progresses into Severe NASH when Physiological Mechanisms of Tissue Homeostasis Collapse", Ann Hepatol, (20180000), vol. 17, pages 182 - 186
    - LI, Z.WANG, C.WANG, Z. et al., "Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds", Nature, (20190000), vol. 575, doi:10.1038/s41586-019-1722-1, pages 203 - 209, XP036932218

DOI:   http://dx.doi.org/10.1038/s41586-019-1722-1
    - ZHU et al., Sensors (Basel, (20160000), vol. 16, no. 3, page 378
    - FEI et al., J Biomed Opt, (20100000), vol. 15, no. 1, page 016018
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