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Extract from the Register of European Patents

EP About this file: EP4225761

EP4225761 - MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  14.07.2023
Database last updated on 14.11.2024
FormerThe international publication has been made
Status updated on  16.04.2022
Formerunknown
Status updated on  15.11.2021
Most recent event   Tooltip28.10.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Vertex Pharmaceuticals Incorporated
50 Northern Avenue
Boston, MA 02210 / US
[2023/33]
Inventor(s)01 / McCARTNEY, Jason
Boston, Massachusetts 02210 / US
02 / ABELA, Alexander Russell
Boston, Massachusetts 02210 / US
03 / ABRAHAM, Sunny
Boston, Massachusetts 02210 / US
04 / ANDERSON, Corey Don
Boston, Massachusetts 02210 / US
05 / ARUMUGAM, Vijayalaksmi
Boston, Massachusetts 02210 / US
06 / CHAU, Jaclyn
Boston, Massachusetts 02210 / US
07 / CLEMENS, Jeremy
Boston, Massachusetts 02210 / US
08 / CLEVELAND, Thomas
Boston, Massachusetts 02210 / US
09 / COON, Timothy Richard
Boston, Massachusetts 02210 / US
10 / DWIGHT, Timothy A.
Boston, Massachusetts 02210 / US
11 / FRIEMAN, Bryan A.
Boston, Massachusetts 02210 / US
12 / GROOTENHUIS, Peter
(Deceased) / US
13 / HADIDA RUAH, Sara Sabina
Boston, Massachusetts 02210 / US
14 / ISHIHARA, Yoshihiro
Boston, Massachusetts 02210 / US
15 / KHATUYA, Haripada
Boston, Massachusetts 02210 / US
16 / KRENITSKY, Paul
Boston, Massachusetts 02210 / US
17 / MILLER, Mark Thomas
Boston, Massachusetts 02210 / US
18 / PARASELLI, Prasuna
Boston, Massachusetts 02210 / US
19 / PIERRE, Fabrice
Boston, Massachusetts 02210 / US
20 / SILINA, Alina
Boston, Massachusetts 02210 / US
21 / TRAN, Joe A.
Boston, Massachusetts 02210 / US
22 / ZHOU, Jinglan
Boston, Massachusetts 02210 / US
 [2023/33]
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2023/33]
Application number, filing date21801353.006.10.2021
[2023/33]
WO2021US53855
Priority number, dateUS202063088759P07.10.2020         Original published format: US 202063088759 P
[2023/33]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2022076620
Date:14.04.2022
Language:EN
[2022/15]
Type: A1 Application with search report 
No.:EP4225761
Date:16.08.2023
Language:EN
The application published by WIPO in one of the EPO official languages on 14.04.2022 takes the place of the publication of the European patent application.
[2023/33]
Search report(s)International search report - published on:EP14.04.2022
ClassificationIPC:C07D515/04, A61P43/00, A61K31/519
[2023/33]
CPC:
C07D515/04 (EP); C07D515/08 (US); A61K31/529 (US);
A61K31/5377 (US); A61K45/06 (US); A61P43/00 (EP);
C07D515/18 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/33]
TitleGerman:MODULATOREN DES REGULATORS DER TRANSMEMBRAN-LEITFÄHIGKEIT BEI ZYSTISCHER FIBROSE[2023/33]
English:MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR[2023/33]
French:MODULATEURS DU RÉGULATEUR DE LA CONDUCTANCE TRANSMEMBRANAIRE DE LA FIBROSE KYSTIQUE[2023/33]
Entry into regional phase03.05.2023National basic fee paid 
03.05.2023Designation fee(s) paid 
03.05.2023Examination fee paid 
Examination procedure03.05.2023Examination requested  [2023/33]
03.05.2023Date on which the examining division has become responsible
30.11.2023Amendment by applicant (claims and/or description)
Fees paidRenewal fee
03.05.2023Renewal fee patent year 03
28.10.2024Renewal fee patent year 04
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Cited inInternational search[I]WO2019161078  (VERTEX PHARMA [US]) [I] 1-27* example - *;
 [XP]WO2020206080  (VERTEX PHARMA [US]) [XP] 1-27 * example -; claim - *;
 [IP]WO2021030552  (VERTEX PHARMA [US]) [IP] 1-27 * example -; claim - *
by applicantWO2006002421
 WO2007056341
 WO2007079139
 US2009131492
 WO2009073757
 WO2009076142
 WO2010019239
 WO2010037066
 WO2010053471
 WO2010108162
 WO2011119984
 WO2011127421
 WO2011133751
 WO2011133951
 WO2012158885
 WO2014071122
 WO2014078842
 US8865902
 WO2015160787
    - CUTTING, G. R et al., Nature, (19900000), vol. 346, pages 366 - 369
    - DEAN, M. et al., Cell, (19900000), vol. 61, no. 863, page 870
    - KEREM, B-S et al., Science, (19890000), vol. 245, pages 1073 - 1080
    - KEREM, B-S et al., Proc. Natl. Acad. Sci. USA, (19900000), vol. 87, pages 8447 - 8451
    - QUINTON, P. M., FASEB J, (19900000), vol. 4, pages 2709 - 2727
    - DALEMANS et al., Nature Lond, (19910000), vol. 354, pages 526 - 528
    - PASYKFOSKETT, J. Cell. Biochem., (19950000), vol. 270, pages 12347 - 50
    - S. M. BERGE et al., J. Pharmaceutical Sciences, (19770000), vol. 66, pages 1 - 19
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.