EP4244248 - FAB HIGH MANNOSE GLYCOFORMS [Right-click to bookmark this link] | Status | Request for examination was made Status updated on 18.08.2023 Database last updated on 01.01.2025 | |
Former | The international publication has been made Status updated on 21.05.2022 | ||
Former | unknown Status updated on 19.11.2021 | Most recent event Tooltip | 22.11.2024 | New entry: Renewal fee paid | Applicant(s) | For all designated states F. Hoffmann-La Roche AG Grenzacherstrasse 124 4070 Basel / CH | [2023/38] | Inventor(s) | 01 /
JOERIS, Klaus 82377 Penzberg / DE | 02 /
OEZDEN, Neslihan 82377 Penzberg / DE | 03 /
RICHTER, Wolfgang 4070 Basel / CH | 04 /
SCHMIDT, Britta 82377 Penzberg / DE | 05 /
HOFMANN, Carsten 4070 Basel / CH | 06 /
LAU, Wilma 82377 Penzberg / DE | 07 /
STAACK, Roland 82377 Penzberg / DE | [2023/38] | Representative(s) | Skolaut, Alexander Roche Diagnostics GmbH Patentabteilung LPAA....6164 Nonnenwald 2 82377 Penzberg / DE | [N/P] |
Former [2023/38] | Mewburn Ellis LLP Aurora Building Counterslip Bristol BS1 6BX / GB | Application number, filing date | 21802364.6 | 04.11.2021 | [2023/38] | WO2021EP80692 | Priority number, date | EP20200207804 | 16.11.2020 Original published format: EP 20207804 | [2023/38] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2022101088 | Date: | 19.05.2022 | Language: | EN | [2022/20] | Type: | A1 Application with search report | No.: | EP4244248 | Date: | 20.09.2023 | Language: | EN | The application published by WIPO in one of the EPO official languages on 19.05.2022 takes the place of the publication of the European patent application. | [2023/38] | Search report(s) | International search report - published on: | EP | 19.05.2022 | Classification | IPC: | C07K16/18, A61K39/00 | [2023/38] | CPC: |
C07K16/18 (EP,IL,KR,US);
C07K16/2881 (US);
A61K2039/505 (EP,IL,KR,US);
C07K2317/14 (EP,IL,KR);
C07K2317/31 (US);
C07K2317/41 (EP,IL,KR,US);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2023/38] | Validation states | MA | 22.05.2023 | Title | German: | FAB-GLYCOFORMEN MIT HOHEM MANNOSEGEHALT | [2023/38] | English: | FAB HIGH MANNOSE GLYCOFORMS | [2023/38] | French: | GLYCOFORMES FAB À HAUTE TENEUR EN MANNOSE | [2023/38] | Entry into regional phase | 22.05.2023 | National basic fee paid | 22.05.2023 | Designation fee(s) paid | 22.05.2023 | Examination fee paid | Examination procedure | 22.05.2023 | Examination requested [2023/38] | 22.05.2023 | Date on which the examining division has become responsible | 21.12.2023 | Amendment by applicant (claims and/or description) | Fees paid | Renewal fee | 22.11.2023 | Renewal fee patent year 03 | 21.11.2024 | Renewal fee patent year 04 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [XA]EP1960428 (HOFFMANN LA ROCHE [CH]) [X] 1,3,5,18,19 * the whole document * [A] 2,4,6-17,20; | [A] - VAN DE BOVENKAMP FLEUR S. ET AL, "The Emerging Importance of IgG Fab Glycosylation in Immunity", US, vol. 196, no. 4, doi:10.4049/jimmunol.1502136, ISSN 0022-1767, (20160215), pages 1435 - 1441, THE JOURNAL OF IMMUNOLOGY, URL: https://www.jimmunol.org/content/jimmunol/196/4/1435.full.pdf, XP055797847 [A] 1-20 * the whole document * DOI: http://dx.doi.org/10.4049/jimmunol.1502136 | [XI] - HUANG L ET AL, "Impact of variable domain glycosylation on antibody clearance: An LC/MS characterization", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS, AMSTERDAM, NL, vol. 349, no. 2, doi:10.1016/J.AB.2005.11.012, ISSN 0003-2697, (20060215), pages 197 - 207, (20060215), XP024941990 [X] 1,3,5,18,19 * the whole document * [I] 2,4,6-17,20 DOI: http://dx.doi.org/10.1016/j.ab.2005.11.012 | [A] - A. M. GOETZE ET AL, "High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans", GLYCOBIOLOGY, (20110701), vol. 21, no. 7, doi:10.1093/glycob/cwr027, ISSN 0959-6658, pages 949 - 959, XP055169019 [A] 1-20 * the whole document * DOI: http://dx.doi.org/10.1093/glycob/cwr027 | by applicant | US4676980 | EP0307247 | US4816567 | EP0404097 | WO9301161 | WO9316185 | US5571894 | US5587458 | WO9725428 | US5731168 | US5770429 | US5821337 | WO9850431 | US5869046 | US6075181 | US6150584 | US6248516 | US6982321 | US7041870 | US7087409 | US7189826 | US2007061900 | US2008069820 | EP1960428 | US7527791 | WO2009089004 | WO2011034605 | EP1960428 | WO2015095539 | EP3356400 | - ZHANG et al., Drug Discovery Today, (20160000), vol. 21, pages 740 - 765 | - HIGEL et al., European Journal of Pharmaceutics and Biopharmaceutics, (20160000), vol. 100, pages 94 - 100 | - BIERMANN et al., Lupus, (20160000), vol. 25, pages 934 - 942 | - JEFFERIS, Nature, (20090000), vol. 8, pages 226 - 234 | - MILLWARD et al., Biologicals, (20080000), vol. 36, pages 41 - 47 | - FINKEBANKS, "UW Tacoma Digital Commons", SIAS Faculty Digital Publications, URL: https://diitalcommons.tacoma.uw.edu/iaspub/825 | - BOVENKAMP et al., J.Immunology, (20160000), vol. 196, pages 1435 - 1441 | - TACHIBANA et al., Cytotechnology, (19940000), vol. 16, pages 151 - 157 | - HOSSLER et al., Glycobiology, (20090000), vol. 19, no. 9, pages 936 - 949 | - EHRET et al., Biotechnol & Bioeng, (20190000), vol. 116, pages 816 - 830 | - FAN et al., Biotech & Bioeng, (20150000), vol. 112, no. 3, pages 521 - 535 | - HUANG et al., Anal. Biochem., (20060000), vol. 349, pages 197 - 207 | - ST AMAND et al., Biotechnol Bioeng, (20140000), vol. 111, no. 10, pages 1957 - 70 | - FLATMAN et al., J. Chromatogr. B, (20070000), vol. 848, pages 79 - 87 | - MORRISON et al., P.N.A.S, (19840000), vol. 81, pages 6851 - 6855 | - ALMAGROFRANSSON, Front. Biosci., (20080000), vol. 13, pages 1619 - 1633 | - RIECHMANN et al., Nature, (19880000), vol. 332, pages 323 - 329 | - QUEEN et al., Proc. Nat'l Acad. Sci. USA, (19890000), vol. 86, pages 10029 - 10033 | - DALL'ACQUA et al., Methods, (20050000), vol. 36, pages 61 - 68 | - PADLAN, Mol. Immunol., (19910000), vol. 28, pages 489 - 498 | - KLIMKA et al., Br. J. Cancer, (20000000), vol. 83, pages 252 - 260 | - PRESTA et al., J. Immunol., (19930000), vol. 151, page 2623 | - CARTER et al., Proc. Natl. Acad. Sci. USA, (19920000), vol. 89, page 4285 | - BACA et al., J. Biol. Chem., (19970000), vol. 272, pages 10678 - 10684 | - ROSOK et al., J. Biol. Chem., (19960000), vol. 271, pages 22611 - 22618 | - VAN DIJKVAN DE WINKEL, Curr. Opin. Pharmacol., (20010000), vol. 5, pages 368 - 74 | - LONBERG, Curr. Opin. Immunol., (20080000), vol. 20, pages 450 - 459 | - LONBERG, Nat. Biotech., (20050000), vol. 23, pages 1117 - 1125 | - KOZBOR, J. Immunol., (19840000), vol. 133, page 3001 | - BRODEUR et al., Monoclonal Antibody Production Techniques and Applications, Marcel Dekker, Inc., (19870000), pages 51 - 63 | - TUTT et al., J. Immunol., (19910000), vol. 147, page 60 | - LI et al., Proc. Natl. Acad. Sci. USA, (20060000), vol. 103, pages 3557 - 3562 | - NI, Xiandai Mianyixue, (20060000), vol. 26, no. 4, pages 265 - 268 | - VOLLMERSBRANDLEIN, Histology and Histopathology, (20050000), vol. 20, no. 3, pages 927 - 937 | - VOLLMERSBRANDLEIN, Methods and Findings in Experimental and Clinical Pharmacology, (20050000), vol. 27, no. 3, pages 185 - 91 | - HOLLIGERHUDSON, Nature Biotechnology, (20050000), vol. 23, pages 1126 - 1136 | - HUDSON et al., Nat. Med., (20030000), vol. 9, pages 129 - 134 | - HOLLINGER et al., Proc. Natl. Acad. Sci. USA, (19930000), vol. 90, pages 6444 - 6448 | - GRUBER et al., J. Immunol., (19940000), vol. 152, pages 5368 - 315 | - MILSTEINCUELLO, Nature, (19830000), vol. 305, page 537 | - ATWELL et al., J. Mol. Biol., (19970000), vol. 270, page 26 | - BRENNAN et al., Science, (19850000), vol. 229, page 81 | - KOSTELNY et al., J. Immunol., (19920000), vol. 148, no. 5, pages 1547 - 1553 | - LIU et al., J. Pharmaceutical Sciences, (20150000), vol. 104, pages 1866 - 1884 | - MONTREUIL, Polysaccharides in Medicinal Applications, (19960000), vol. 273-327 | - FAN et al., Biotechnol. Bioeng., (20150000), vol. 112, no. 3, pages 521 - 535 | - BARNESSATO, Cell, (19800000), vol. 22, page 649 | - GRAHAM et al., J.Gen.Virol., (19770000), vol. 36, page 59 | - BAUMANN et al., J.Cell Biol., (19800000), vol. 85 | - MATHER et al., Annals N.Y.Acad.Sci., (19820000), vol. 383, page 44 | - SIMONSENLEVINSON, P.N.A.S., (19830000), vol. 80, pages 2495 - 2499 |