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EP4206222
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EP About this file: EP4206222
| EP4206222 - SIGNAL PEPTIDE FOR REDUCING END HETEROGENEITY OF HETEROLOGOUS POLYPEPTIDE [Right-click to bookmark this link] | Status | Request for examination was made Status updated on 02.06.2023 Database last updated on 10.07.2024 | |
| Former | The international publication has been made Status updated on 05.03.2022 | Most recent event Tooltip | 14.03.2024 | Supplementary search report | published on 10.04.2024 [2024/15] | Applicant(s) | For all designated states Jiangsu Hengrui Pharmaceuticals Co., Ltd. No. 7 Kunlunshan Road Economic and Technological Development Zone Lianyungang, Jiangsu 222047 / CN | For all designated states Shanghai Hengrui Pharmaceutical Co., Ltd. No.279 Wenjing Road Minhang District Shanghai 200245 / CN | [2023/27] | Inventor(s) | 01 /
ZHOU, Songtao Shanghai 200245 / CN | 02 /
LIU, Xun Shanghai 200245 / CN | [2023/27] | Representative(s) | Dragotti & Associati S.R.L., et al Via Nino Bixio, 7 20129 Milano / IT | [N/P] |
| Former [2023/27] | Sonzogni, Laura Gabriella, et al Dragotti & Associati S.r.l. Via Nino Bixio, 7 20129 Milano / IT | Application number, filing date | 21860507.9 | 27.08.2021 | [2023/27] | WO2021CN114911 | Priority number, date | CN202010882873 | 28.08.2020 Original published format: CN202010882873 | CN202110958128 | 20.08.2021 Original published format: CN202110958128 | [2023/27] | Filing language | ZH | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2022042673 | Date: | 03.03.2022 | Language: | ZH | [2022/09] | Type: | A1 Application with search report | No.: | EP4206222 | Date: | 05.07.2023 | Language: | EN | [2023/27] | Search report(s) | International search report - published on: | CN | 03.03.2022 | (Supplementary) European search report - dispatched on: | EP | 13.03.2024 | Classification | IPC: | C07K16/00, C07K14/00, C12N15/00, A61K39/00, C12P21/08 | [2023/27] | CPC: |
C07K16/065 (EP);
C07K16/283 (US);
A61K39/00 (EP);
C07K14/00 (EP);
C07K16/28 (EP,US);
C07K16/30 (EP);
C07K16/32 (EP);
C07K2317/14 (EP,US);
C07K2317/24 (EP,US);
C07K2317/40 (EP);
C07K2317/52 (EP);
C07K2317/565 (US);
C07K2317/567 (US);
C07K2317/732 (EP,US);
C07K2317/77 (EP);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2023/27] | Title | German: | SIGNALPEPTID ZUR REDUZIERUNG DER HETEROGENITÄT DES ENDES EINES HETEROLOGEN POLYPEPTIDS | [2023/27] | English: | SIGNAL PEPTIDE FOR REDUCING END HETEROGENEITY OF HETEROLOGOUS POLYPEPTIDE | [2023/27] | French: | PEPTIDE SIGNAL POUR RÉDUIRE L'HÉTÉROGÉNÉITÉ FINALE D'UN POLYPEPTIDE HÉTÉROLOGUE | [2023/27] | Entry into regional phase | 20.02.2023 | Translation filed | 20.02.2023 | National basic fee paid | 20.02.2023 | Search fee paid | 20.02.2023 | Designation fee(s) paid | 20.02.2023 | Examination fee paid | Examination procedure | 20.02.2023 | Examination requested [2023/27] | Fees paid | Renewal fee | 26.07.2023 | Renewal fee patent year 03 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X]WO03102017 (CENTOCOR INC [US]) [X] 1,2,4,6,7,10-12 * CNTO 4164;; sequence 9 *; | [XY]WO2007143090 (AVEO PHARMACEUTICALS INC [US], et al) [X] 1,2,4,6,7,10-12 * paragraph [0148] - paragraph [0180]; table 2 * * clones 1D3, 3A3,1F3, 3A12; paragraph [0208]; figure 4 * * clones 2P8 and 3B6;; figure 2 * [Y] 1-15; | [Y]US2015225482 (SONG ZHIWEI [SG]) [Y] 1-15 * abstract *; | [Y] - HARYADI RYAN ET AL, "Optimization of Heavy Chain and Light Chain Signal Peptides for High Level Expression of Therapeutic Antibodies in CHO Cells", PLOS ONE, US, (20150201), vol. 10, no. 2, doi:10.1371/journal.pone.0116878, ISSN 1932-6203, page e0116878, XP093133740 [Y] 1-15 * abstract * DOI: http://dx.doi.org/10.1371/journal.pone.0116878 | [Y] - GIBSON S J ET AL, "N-terminal or signal peptide sequence engineering prevents truncation of human monoclonal antibody light chains", BIOTECHNOLOGY AND BIOENGINEERING, JOHN WILEY, HOBOKEN, USA, (20170508), vol. 114, no. 9, doi:10.1002/BIT.26301, ISSN 0006-3592, pages 1970 - 1977, XP071115450 [Y] 1-15 * abstract * DOI: http://dx.doi.org/10.1002/bit.26301 |