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Extract from the Register of European Patents

EP About this file: EP4225311

EP4225311 - TREATMENT OF SKIN DISEASES [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  14.07.2023
Database last updated on 03.09.2024
FormerThe international publication has been made
Status updated on  16.04.2022
Most recent event   Tooltip08.12.2023Change: Validation statespublished on 10.01.2024  [2024/02]
08.12.2023Change - extension statespublished on 10.01.2024  [2024/02]
Applicant(s)For all designated states
Ichilov Tech Ltd.
6 Weizmann Street
6423906 Tel-Aviv / IL
[2023/33]
Inventor(s)01 / SPRECHER, Eli
5320025 Givatayim / IL
02 / SARIG, Ofer
3009500 Ramat-Yishai / IL
 [2023/33]
Representative(s)Robba, Pierpaolo
Interpatent S.R.L.
Via Caboto, 35
10129 Torino / IT
[2023/33]
Application number, filing date21877136.805.10.2021
[2023/33]
WO2021IL51197
Priority number, dateUS202063087353P05.10.2020         Original published format: US 202063087353 P
[2023/33]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2022074649
Date:14.04.2022
Language:EN
[2022/15]
Type: A1 Application with search report 
No.:EP4225311
Date:16.08.2023
Language:EN
The application published by WIPO in one of the EPO official languages on 14.04.2022 takes the place of the publication of the European patent application.
[2023/33]
Search report(s)International search report - published on:IL14.04.2022
ClassificationIPC:A61K31/4745, A61P17/06, A61P17/10, A61P17/00, A61P29/00, A61P35/00
[2023/33]
CPC:
A61P17/00 (EP,IL); A61K31/4745 (EP,IL,US); A61K9/0014 (US);
A61P17/06 (EP,IL,US); A61P17/10 (EP,IL); A61P29/00 (EP,IL,US);
A61P35/00 (EP,IL) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/33]
TitleGerman:BEHANDLUNG VON HAUTERKRANKUNGEN[2023/33]
English:TREATMENT OF SKIN DISEASES[2023/33]
French:TRAITEMENT DE MALADIES DE LA PEAU[2023/33]
Entry into regional phase05.05.2023National basic fee paid 
05.05.2023Search fee paid 
05.05.2023Designation fee(s) paid 
05.05.2023Examination fee paid 
Examination procedure05.05.2023Amendment by applicant (claims and/or description)
05.05.2023Examination requested  [2023/33]
Fees paidRenewal fee
25.10.2023Renewal fee patent year 03
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Cited inInternational search[X]WO2005007129  (ANGIOTECH INT AG [CH], et al) [X] 1-20 * Abstract; page 5 lines 10-12; page 35 line 16 to page 36 line 14; claims 1, 38-43, and 50-54. *;
 [YX]  - L. XI-RAN ET AL., "Topical camptothecine in treatment of psoriasis", (19880101), vol. 27, no. 7, pages 475 - 476, XP002210951 [Y] 1-20 * The whole document. * [X] 1,2,6-20
 [YX]  - C. CHING-JUNG ET AL., "Effect of topical use of camptothecine-dimethyl sulfoxide solution in psoriasis", (19750101), vol. 1, no. 5, pages 355 - 360, XP002210950 [Y] 1-20 * The whole document. * [X] 1,2,6-20
 [YX]  - Lin Xi-Ran, Huang Tian, Yang Chun-Mei, Tu Cai-Xia, Yang Guo-Ling, "Clinical trial and experimental study on treating psoriasis with camptothecine", Chinese medical journal, (19881231), vol. 101, no. 6, doi:10.5555/cmj.0366-6999.101.06.p427.01, pages 427 - 430, XP055919194 [Y] 1-20 * The whole document. * [X] 1,2,6-20

DOI:   http://dx.doi.org/10.5555/cmj.0366-6999.101.06.p427.01
 [YX]  - Venâncio João Hélio, Andrade Lígia Marquez, Esteves Najla Locatelli Santos, Brito Lara Barroso, Valadares Marize Campos, Oliveira Gisele Augusto Rodrigues, Lima Eliana Martins, Marreto Ricardo Neves, Gratieri Tais, Taveira Stephânia Fleury, "Topotecan-loaded lipid nanoparticles as a viable tool for the topical treatment of skin cancers", Journal of pharmacy and pharmacology : JPP, John Wiley & Sons Ltd, London, GB, GB , (20170905), vol. 69, no. 10, doi:10.1111/jphp.12772, ISSN 0022-3573, pages 1318 - 1326, XP055919198 [Y] 1-20 * Abstract. * [X] 1,3,6,7,12,16-20

DOI:   http://dx.doi.org/10.1111/jphp.12772
 [YX]  - Daud Adil, Munster Pamela, Hausheer Frederick, Apptec Wuxi, Sullivan Daniel M, "Drug discovery View project HDL Modulation View project", Clinical cancer research, doi:10.1158/1078-0432.CCR-04-1722·Source:, (20050415), Clinical cancer research, URL: https://www.researchgate.net/profile/Frederick-Hausheer/publication/7899014_Phase_II_Trial_of_Karenitecin_in_Patients_with_Malignant_Melanoma_Clinical_and_Translational_Study/links/5908e1cba6fdcc496167935d/Phase-II-Trial-of-Karenitecin-in-Patients-with-Malignant-Melanoma-Clinical-and-Translational-Study.pdf, XP055919200 [Y] 1-20 * Abstract, table 1, and page 3013. * [X] 1,4,7,12

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-04-1722·Source:
 [YX]  - Galatage Sunil T., Hebalkar Aditya S., Gote Raviraj V., Mali Omkar R., Killedar Suresh G., Bhagwat Durgacharan A., Kumbhar Vijay M., "Design and characterization of camptothecin gel for treatment of epidermoid carcinoma", Future Journal of Pharmaceutical Sciences, (20201201), vol. 6, no. 1, doi:10.1186/s43094-020-00066-6, XP055919202 [Y] 1-20 * Abstract. * [X] 1,2,6,7,12,16-20

DOI:   http://dx.doi.org/10.1186/s43094-020-00066-6
 [YX]  - O'REILLY S., ROWINSKY E.K., "THE CLINICAL STATUS OF IRINOTECAN (CPT-11), A NOVEL WATER SOLUBLE CAMPTOTHECIN ANALOGUE: 1996.", CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY, (19990312), vol. 24, no. 1, pages 47 - 70, XP000922639 [Y] 1-20 * Figure 4 (page 50), table 5 (page 57) and page 61. * [X] 1,4-7,12
 [Y]  - Rossi Sharyn L.; Lumpkin Casey J.; Harris Ashlee W.; Holbrook Jennifer; Gentillon Cinsley; McCahan Suzanne M.; Wang Wenlan; Butchbach Matthew E.R., "Identification of early gene expression changes in primary cultured neurons treated with topoisomerase I poisons", Biochemical and Biophysical Research Communications, Elsevier, Amsterdam NL, Amsterdam NL , (20160915), vol. 479, no. 2, doi:10.1016/j.bbrc.2016.09.068, ISSN 0006-291X, pages 319 - 324, XP029755016 [Y] 8 * Abstract. *

DOI:   http://dx.doi.org/10.1016/j.bbrc.2016.09.068
 [X]  - Sun Jun, Dou Wei, Zhao Yi, Hu Jinhong, "A comparison of the effects of topical treatment of calcipotriol, camptothecin, clobetasol and tazarotene on an imiquimod-induced psoriasis-like mouse model", Immunopharmacology and Immunotoxicology, US , (20140201), vol. 36, no. 1, doi:10.3109/08923973.2013.862542, ISSN 0892-3973, pages 17 - 24, XP009535542 [X] 17,19,20 * Abstract. *

DOI:   http://dx.doi.org/10.3109/08923973.2013.862542
 [A]  - Sun Jun, Han Jinzhao, Zhu Quangang, Li Zhen, Hu Jinhong, "Camptothecin Fails to Induce Apoptosis in Tumor Necrosis Factor-Alpha-Treated HaCaT Cells", Pharmacology, CH , (20120301), vol. 89, no. 1-2, doi:10.1159/000335370, ISSN 0031-7012, pages 58 - 63, XP009535541 [A] 1-20

DOI:   http://dx.doi.org/10.1159/000335370
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