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Extract from the Register of European Patents

EP About this file: EP4074323

EP4074323 - INHIBITING OR ALLEVIATING AGENT FOR A BETA-INDUCED DAMAGE [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  16.09.2022
Database last updated on 19.10.2024
Most recent event   Tooltip28.03.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Liu, Jun
Department of Neurology
Sun Yat-Sen Memorial Hospital
Sun Yat-Sen University
Guangzhou, Guangdong 510120 / CN
For all designated states
Nippon Zoki Pharmaceutical Co., Ltd.
2-3, Hiranomachi 4-chome
Chuo-ku
Osaka-shi, Osaka 541-0046 / JP
[2022/42]
Inventor(s)01 / LIU, Jun
Guangdong, 510120 / CN
 [2022/42]
Representative(s)Abel & Imray LLP
Westpoint Building
James Street West
Bath BA1 2DA / GB
[2022/42]
Application number, filing date22174964.106.03.2017
[2022/42]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP4074323
Date:19.10.2022
Language:EN
[2022/42]
Search report(s)(Supplementary) European search report - dispatched on:EP20.09.2022
ClassificationIPC:A61K35/36, A61K35/00, A61P25/16
[2022/42]
CPC:
A61P25/16 (EP,CN); G01N33/5023 (CN,KR); G01N33/6872 (CN,KR);
A61K35/36 (EP,CN,US); A61K9/0019 (CN,US); A61K9/0053 (CN,US);
A61P25/28 (CN,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/42]
TitleGerman:MITTEL ZUR HEMMUNG ODER LINDERUNG VON BETA-INDUZIERTEN SCHÄDEN[2022/42]
English:INHIBITING OR ALLEVIATING AGENT FOR A BETA-INDUCED DAMAGE[2022/42]
French:AGENT INHIBITEUR OU ATTÉNUANT POUR DOMMAGES INDUITS PAR A BETA[2022/42]
Examination procedure23.05.2022Examination requested  [2022/42]
18.04.2023Amendment by applicant (claims and/or description)
18.04.2023Date on which the examining division has become responsible
Parent application(s)   TooltipEP17899766.4  / EP3592369
Fees paidRenewal fee
23.05.2022Renewal fee patent year 03
23.05.2022Renewal fee patent year 04
23.05.2022Renewal fee patent year 05
23.05.2022Renewal fee patent year 06
23.03.2023Renewal fee patent year 07
27.03.2024Renewal fee patent year 08
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Documents cited:Search[A]EP2364711  (VANWORLD PHARMACEUTICAL RUGAO CO LTD [CN])[A] 1-8;
 [X]  - FUKUDA Y ET AL, "Stimulated neuronal expression of brain-derived neurotrophic factor by Neurotropin", MOLECULAR AND CELLULAR NEUROSCIENCES, SAN DIEGO, US, vol. 45, no. 3, ISSN 1044-7431, (20101101), pages 226 - 233, (20100628), XP027279150 [X] 1-8 * Introduction, page 228-right-hand column, paragraph 2, page 231, left-hand column, paragraph 2, figures 4 and 5, discussion; *
by applicantWO2016194816
    - FUKUDA YBERRY TLNELSON M et al., "Stimulated neuronal expression of brain-derived neurotrophic factor by Neurotropin", Mol Cell Neurosci, (20100000), vol. 45, pages 226 - 233, XP027279150
    - NAKAJO Y, YANG D, TAKAHASHI JC, ZHAO Q, KATAOKA H, YANAMOTO H, "ERV enhances spatial learning and prevents the development of infarcts, accompanied by upregulated BDNF in the cortex", Brain Res, (20150000), vol. 1610, doi:10.1016/j.brainres.2015.03.042, pages 110 - 123, XP029223152

DOI:   http://dx.doi.org/10.1016/j.brainres.2015.03.042
    - KIMURA H, NAKAMURA S, OKAMOTO K, TOYAMA I, WATANABE M, IKEUCHI K, "A pilot study for clinical applications of Neurotropin to senile patients with dementia", Pharmacol Ther, (19870000), vol. 15, pages 407 - 423
    - HOSHINO YNAKAMURA TSATO AMISHIMA MYODOI JNAKAMURA H, "Neurotropin demonstrates cytoprotective effects in lung cells through the induction of thioredoxin-1", Am J Resp Cell Mol, (20070000), vol. 37, doi:10.1165/rcmb.2006-0402OC, pages 438 - 446, XP002555409

DOI:   http://dx.doi.org/10.1165/rcmb.2006-0402OC
    - LIU JLI LSUO WZ, "HT22 hippocampal neuronal cell line possesses functional cholinergic properties", Life Sci, (20090000), vol. 84, pages 267 - 271
    - ZHAO ZYLUAN PHUANG SX et al., "Edaravone protects HT22 neurons from H20 -induced Apoptosis by Inhibiting the MAPK Signaling Pathway", CNS Neurosci Ther, (20130000), vol. 19, pages 163 - 169
    - FAN SZHANG BLUAN P et al., "PI3K/AKT/mTOR/p70S6K Pathway is involved in Ap25-35-induced autophagy", Biomed Res Int, (20150000), vol. 2015, pages 1 - 9
    - ZHAO ZYLUAN PHUANG SX et al., "Edaravone protects HT22 neurons from H 0 -induced Apoptosis by Inhibiting the MAPK Signaling Pathway", CNS Neurosci Ther, (20130000), vol. 19, pages 163 - 169
    - BAO FXSHI HYQI L et al., "Mitochondrial Membrane Potential-dependent Endoplasmic Reticulum Fragmentation is an Important Step in Neuritic Degeneration", CNS Neurosci Ther, (20160000), vol. 22, pages 648 - 660
    - SCHWAB CSTEELE JCMCGEER PL, "Dystrophic neurites are associated with the majority of early stage extracellular neurofibrillary tangles in parkinsonism dementia complex of Guam", Acta Neuropathol, (19970000), vol. 94, pages 486 - 492
    - SCHWAB CHOSOKAWA MMCGEER PL, "Transgenic mice overexpressing amyloid beta protein are an incomplete model of alzheimer disease", Exp Neurol, (20040000), vol. 188, doi:10.1016/j.expneurol.2004.03.016, pages 52 - 64, XP004620642

DOI:   http://dx.doi.org/10.1016/j.expneurol.2004.03.016
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