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Extract from the Register of European Patents

EP About this file: EP4332221

EP4332221 - THREOSE NUCLEIC ACID ANTISENSE OLIGONUCLEOTIDES AND METHODS THEREOF [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  22.03.2024
Database last updated on 03.09.2024
FormerThe application has been published
Status updated on  02.02.2024
Most recent event   Tooltip22.03.2024Withdrawal of applicationpublished on 24.04.2024  [2024/17]
Applicant(s)For all designated states
Roche Innovation Center Copenhagen A/S
Fremtidsvej 3
2970 Hørsholm / DK
For all designated states
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[2024/10]
Representative(s)Rodriguez Novoa, Lorena
F. Hoffmann-La Roche AG Patent Department
Grenzacherstrasse 124
4070 Basel / CH
[2024/10]
Application number, filing date22192656.129.08.2022
[2024/10]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP4332221
Date:06.03.2024
Language:EN
[2024/10]
Search report(s)(Supplementary) European search report - dispatched on:EP22.05.2023
ClassificationIPC:C12N15/113, C12N15/11
[2024/10]
CPC:
C12N15/111 (EP); C12N15/113 (EP); C12N2310/11 (EP);
C12N2310/315 (EP); C12N2310/319 (EP); C12N2310/32 (EP);
C12N2310/3231 (EP); C12N2310/3341 (EP); C12N2310/341 (EP) (-)
C-Set:
C12N2310/321, C12N2310/3525 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2024/10]
Extension statesBANot yet paid
MENot yet paid
Validation statesKHNot yet paid
MANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:THREOSE-NUKLEINSÄURE-ANTISENSE-OLIGONUKLEOTIDE UND VERFAHREN DAFÜR[2024/10]
English:THREOSE NUCLEIC ACID ANTISENSE OLIGONUCLEOTIDES AND METHODS THEREOF[2024/10]
French:OLIGONUCLÉOTIDES ANTISENS D'ACIDE NUCLÉIQUE À THRÉOSE ET PROCÉDÉS ASSOCIÉS[2024/10]
Examination procedure20.12.2022Loss of particular rights, legal effect: Claims
25.01.2023Despatch of communication of loss of particular rights: Claims {1}
15.03.2024Despatch of communication that the application is refused, reason: Examination on filing A.90(5) {1}
19.03.2024Application withdrawn by applicant  [2024/17]
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Documents cited:Search[I]  - WANG FEI ET AL., "Synthetic alpha-L-Threose nucleic acids targeting BcL-2 show gene silencing and in vivo antitumor activity for cancer therapy", APPLIED MATERIALS & INTERFACES, US, (20190926), vol. 11, no. 42, doi:10.1021/acsami.9b14324, ISSN 1944-8244, pages 38510 - 38518, XP093031784 [I] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1021/acsami.9b14324
 [I]  - Wang Fei ET AL., "Supporting Information", (20190926), URL: https://pubs.acs.org/doi/10.1021/acsami.9b14324#, (20230510), XP093045923 [I] 1-15 * the whole document *
 [I]  - LIU LING SUM ET AL., "alpha-L-Threose nucleic acids as biocompatible antisense oligonucleotides for suppressing gene expression in living cells", APPLIED MATERIALS & INTERFACES, US, (20180223), vol. 10, no. 11, doi:10.1021/acsami.8b01180, ISSN 1944-8244, pages 9736 - 9743, XP093031816 [I] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1021/acsami.8b01180
 [I]  - Ling Sum ET AL., "Supporting Information", (20180223), URL: https://pubs.acs.org/doi/10.1021/acsami.8b01180, (20230510), XP093045921 [I] 1-15 * the whole document *
 [A]  - ROBERTS THOMAS C. ET AL., "Advances in oligonucleotide drug delivery", NATURE REVIEWS DRUG DISCOVERY, NATURE PUBLISHING GROUP, GB, vol. 19, no. 10, doi:10.1038/S41573-020-0075-7, ISSN 1474-1776, (20200811), pages 673 - 694, (20200811), XP037256878 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1038/s41573-020-0075-7
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