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EP4302095
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EP About this file: EP4302095
| EP4302095 - METHODS FOR THE MEASUREMENT OF PROTEIN C AND ACTIVATED PROTEIN C [Right-click to bookmark this link] | Status | Request for examination was made Status updated on 08.12.2023 Database last updated on 30.10.2024 | |
| Former | The international publication has been made Status updated on 09.09.2022 | ||
| Former | unknown Status updated on 16.03.2022 | Most recent event Tooltip | 03.05.2024 | Change: Validation states | published on 05.06.2024 [2024/23] | 03.05.2024 | Change - extension states | published on 05.06.2024 [2024/23] | Applicant(s) | For all designated states Consorcio Centro de Investigación Biomédica en Red (CIBER) C/ Monforte de Lemos 3-5 Pabellón 11 28029 Madrid / ES | For all designated states Universitat de València Av Blasco Ibáñez nº 13 46010 Valencia / ES | For all designated states Instituto de Investigación Sanitaria INCLIVA Avda. Menéndez Pelayo 4 acc. 46010 Valencia / ES | [2024/02] | Inventor(s) | 01 /
GARCÍA GIMÉNEZ, José Luis 28029 Madrid / ES | 02 /
PALLARDÓ CALATAYUD, Federico Vicente 46010 Valencia / ES | 03 /
MENA MOLLÁ, Salvador 46010 Valencia / ES | 04 /
CARBONELL MONLEÓN, Nieves 46010 Valencia / ES | [2024/02] | Representative(s) | Hoffmann Eitle Hoffmann Eitle S.L.U. Paseo de la Castellana 140, 3a planta Edificio LIMA 28046 Madrid / ES | [2024/02] | Application number, filing date | 22708174.2 | 01.03.2022 | [2024/02] | WO2022EP55176 | Priority number, date | EP20210382173 | 01.03.2021 Original published format: EP 21382173 | [2024/02] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2022184725 | Date: | 09.09.2022 | Language: | EN | [2022/36] | Type: | A1 Application with search report | No.: | EP4302095 | Date: | 10.01.2024 | Language: | EN | The application published by WIPO in one of the EPO official languages on 09.09.2022 takes the place of the publication of the European patent application. | [2024/02] | Search report(s) | International search report - published on: | EP | 09.09.2022 | Classification | IPC: | G01N33/68, A61K38/48 | [2024/02] | CPC: |
G01N33/6848 (EP);
A61K38/4866 (EP);
A61P31/00 (EP);
C12Y304/21069 (EP);
G01N2333/96461 (EP);
G01N2800/226 (EP);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2024/02] | Title | German: | VERFAHREN ZUR MESSUNG VON PROTEIN C UND AKTIVIERTEM PROTEIN C | [2024/02] | English: | METHODS FOR THE MEASUREMENT OF PROTEIN C AND ACTIVATED PROTEIN C | [2024/02] | French: | PROCÉDÉS DE MESURE DE LA PROTÉINE C ET DE LA PROTÉINE C ACTIVÉE | [2024/02] | Entry into regional phase | 29.09.2023 | National basic fee paid | 29.09.2023 | Designation fee(s) paid | 29.09.2023 | Examination fee paid | Examination procedure | 29.09.2023 | Examination requested [2024/02] | 29.09.2023 | Date on which the examining division has become responsible | 24.04.2024 | Amendment by applicant (claims and/or description) | Fees paid | Renewal fee | 08.03.2024 | Renewal fee patent year 03 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [A]US2003211969 (FISHER CHARLES JACK [US], et al) [A] 1-15* the whole document *; | [Y] - MOHAMMED Y ET AL, "Multiplexed targeted proteomic assay to assess coagulation factor concentrations and thrombosis-associated cancer", vol. 1, no. 15, doi:10.1182/bloodadvances.2017007955, (20170627), pages 1080 - 1087, BLOOD ADVANCES, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728326/pdf/advances007955.pdf, XP055861984 [Y] 1-15 * page 1081, column 2, lines 28-32, 49, 50; section "Determining plasma protein level using LC..." spanning pages 1082 and 1083; page 1083, column 2, paragraph 5; Figure 1; Figure 2 (bottom left); Table 1 (entry about Vitamin K-dependent protein C);; figure 1 * DOI: http://dx.doi.org/10.1182/bloodadvances.2017007955 | [Y] - GAITHER C ET AL, "Determination of the concentration range for 267 proteins from 21 lots of commercial human plasma using highly multiplexed multiple reaction monitoring mass spectrometry", vol. 145, no. 10, doi:10.1039/C9AN01893J, (20200407), pages 3634 - 3644, ANALYST, URL: https://pubs.rsc.org/en/content/articlepdf/2020/an/c9an01893j, XP055861994 [Y] 1-15 * abstract; section "experimental" spanning pages 3635-3637 * DOI: http://dx.doi.org/10.1039/C9AN01893J | [ ] - Gaither C ET AL, "Supplementary Information: Determination of the concentration range for 267 proteins from 21 lots of commercial human plasma using highly multiplexed multiple reaction monitoring mass spectrometry", Analyst, (20200407), pages 1 - 18, URL: https://www.rsc.org/suppdata/c9/an/c9an01893j/c9an01893j1.pdf?_ga=2.176000098.1186142032.1637059600-1825512131.1634738856, (20211116), XP055861997 [ ] * Supplementary Table 1 (entry P04070 on page 8); supplementary Table 3 (entry P04070 on page 12) * | [Y] - SANTANA J ET AL, "Treatment of sepsis: a systematic review of its main concepts", vol. 17, no. Suppl 4, doi:10.1186/cc12962, (20131105), page P63, CRITICAL CARE, URL: https://ccforum.biomedcentral.com/track/pdf/10.1186/cc12962.pdf, XP055862271 [Y] 1,2,5-9,13 * abstract * DOI: http://dx.doi.org/10.1186/cc12962 | [Y] - KARAMARKOVIC A R ET AL, "DISTURBANCES OF PROTEIN C ACTIVITY IN ABDOMINAL SEPSIS: DIAGNOSTIC AND PREDICTIVE IMPORTANCE", INTENSIVE CARE MEDICINE, SPRINGER, (20040901), vol. 30, no. Suppl 1, doi:10.1007/S00134-004-2408-0, page S144, XP037119406 [Y] 1,2,5-9,13 * abstract * DOI: http://dx.doi.org/10.1007/s00134-004-2408-0 | [Y] - SHORR A F ET AL, "Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated)", CRITICAL CARE, (20080404), vol. 12, no. 2, page R45, XP021041422 [Y] 1,2,5-9,13 * title; abstract; page 2, column 2, paragraph "Biomarker evaluations"; page 6, first paragraph of section "discussion" * | [Y] - CHOI QUTE ET AL, "Changes in Plasma Levels of Natural Anticoagulants in Disseminated Intravascular Coagulation: High Prognostic Value of Antithrombin and Protein C in Patients with Underlying Sepsis or Severe Infection", ANNALS OF LABORATORY MEDICINE, (20140301), vol. 34, no. 2, doi:10.3343/alm.2014.34.2.85, pages 85 - 91, XP055862296 [Y] 3-12,14,15 * the whole document, in particular title and abstract * DOI: http://dx.doi.org/10.3343/alm.2014.34.2.85 | [Y] - IBA T ET AL, "Potential diagnostic markers for disseminated intravascular coagulation of sepsis", BLOOD REVIEWS, (20151106), vol. 30, no. 2, doi:10.1016/J.BLRE.2015.10.002, pages 149 - 155, XP029497316 [Y] 3-12,14,15 * title; paragraph 2.1 on page 150 * DOI: http://dx.doi.org/10.1016/j.blre.2015.10.002 | by applicant | US2010028910 | - P MURALIDHAR REDDY et al., "Digestion Completeness of Microwave-Assisted and Conventional Trypsin-Catalyzed Reactions", Journal of the American Society for Mass Spectrometry, (20100300), vol. 21, doi:10.1016/j.jasms.2009.11.006, pages 421 - 424, XP026917623 DOI: http://dx.doi.org/10.1016/j.jasms.2009.11.006 | - PAPAGEORGIOU C et al., "Disseminated Intravascular Coagulation: An Update on Pathogenesis, Diagnosis, and Therapeutic Strategies", Clin Appl Thromb Hemost, (20180000), vol. 24, pages 8S - 28S |