Extract from the Register of European Patents

EP About this file: EP4277613

EP4277613 - PHARMACEUTICAL COMPOSITIONS FOR TREATING BREAST CANCERS AND METHODS OF USES THEREOF [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  31.10.2025
Database last updated on 09.04.2026
FormerRequest for examination was made
Status updated on  20.10.2023
FormerThe international publication has been made
Status updated on  22.07.2022
Most recent event   Tooltip27.02.2026Change: Despatch of examination report + time limit 
Applicant(s)For all designated states
University of Tennessee Research Foundation
600 Henley Street
Knoxville, TN 37996 / US
[2023/47]
Inventor(s)01 / STEINER, Mitchell
Germantown, Tennessee 38139 / US
02 / NARAYANAN, Ramesh
Cordova, Tennessee 38018 / US
03 / AHN, Sunjoo
Daejeon Daejeon 34061 / KR
04 / DALTON, James
Ann Arbor, Michigan 48103 / US
 [2023/47]
Representative(s)Pearl Cohen UK
The Gridiron Building
One Pancras Square
London N1C 4AG / GB
[N/P]
Former [2023/47]Pearl Cohen Zedek Latzer Baratz UK LLP
The Gridiron Building
One Pancras Square
London N1C 4AG / GB
Application number, filing date22740195.714.01.2022
[2023/47]
WO2022US12631
Priority number, dateUS20211715110815.01.2021         Original published format: US202117151108
[2023/47]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2022155543
Date:21.07.2022
Language:EN
[2022/29]
Type: A1 Application with search report 
No.:EP4277613
Date:22.11.2023
Language:EN
The application published by WIPO in one of the EPO official languages on 21.07.2022 takes the place of the publication of the European patent application.
[2023/47]
Search report(s)International search report - published on:US21.07.2022
(Supplementary) European search report - dispatched on:EP21.10.2024
ClassificationIPC:A61K31/277, A61K31/167, A61K45/06, A61K31/506, A61K31/519, A61P35/00
[2024/47]
CPC:
A61K45/06 (EP,IL,KR); A61K31/277 (EP,IL,KR); A61K31/167 (KR);
A61K31/506 (EP,IL,KR); A61K31/519 (EP,IL,KR); A61P35/00 (EP,KR);
A61K2300/00 (IL,KR) (-)
C-Set:
A61K31/277, A61K2300/00 (EP);
A61K31/506, A61K2300/00 (EP);
A61K31/519, A61K2300/00 (EP)
Former IPC [2023/47]A61K31/167, A61K31/277, A61K35/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/47]
TitleGerman:PHARMAZEUTISCHE ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON BRUSTKREBS UND VERFAHREN ZUR VERWENDUNG DAVON[2023/47]
English:PHARMACEUTICAL COMPOSITIONS FOR TREATING BREAST CANCERS AND METHODS OF USES THEREOF[2023/47]
French:COMPOSITIONS PHARMACEUTIQUES POUR LE TRAITEMENT DE CANCERS DU SEIN ET LEURS MÉTHODES D'UTILISATION[2023/47]
Entry into regional phase14.07.2023National basic fee paid 
14.07.2023Search fee paid 
14.07.2023Designation fee(s) paid 
14.07.2023Examination fee paid 
Examination procedure14.07.2023Examination requested  [2023/47]
07.05.2025Amendment by applicant (claims and/or description)
07.05.2025Date on which the examining division has become responsible
30.10.2025Despatch of a communication from the examining division (Time limit: M06)
Fees paidRenewal fee
29.01.2024Renewal fee patent year 03
27.01.2025Renewal fee patent year 04
27.01.2026Renewal fee patent year 05
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Documents cited:Search[XIY] WO2020028593  (ONCTERNAL THERAPEUTICS INC et al.) [X] 1-5,10-11,14-15 * paragraphs [0064] , [ 254] , [ 255] , [ 260]; claim 1 *[I] 1-15 [Y] 1-15
 [XIY] US2017209407  (DALTON JAMES T et al.) [X] 1-5,10-11,14-15 * paragraphs [0086] - [0092] - [ 394] , [ 395] , [ 400]; claim 1 *[I] 1-15 [Y] 1-15
 [Y]   WENFEI JI ET AL: "Combined Androgen receptor blockade overcomes the resistance of breast cancer cells to palbociclib", INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, vol. 15, no. 3, 1 January 2019 (2019-01-01), pages 522 - 532, XP055558235, ISSN: 1449-2288, DOI: 10.7150/ijbs.30572 [Y] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.7150/ijbs.30572
 [Y]   LYONS TOMAS G ET AL: "Androgen Receptor-Targeted Therapy for Breast Cancer", CURRENT BREAST CANCER REPORTS, SPRINGER US, BOSTON, vol. 9, no. 4, 24 October 2017 (2017-10-24), pages 242 - 250, XP036367246, ISSN: 1943-4588, [retrieved on 20171024], DOI: 10.1007/S12609-017-0261-8 [Y] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1007/s12609-017-0261-8
International search[A] US2019111010  (NARAYANAN RAMESH et al.) [A] 1,2 * entire document *
 [A] WO2017223115  (RADIUS HEALTH INC et al.) [A] 1,2 * entire document *
 [A] US2007066568  (DALTON JAMES T et al.) [A] 1,2 * entire document *
Examination  HICKEY THERESA E. ET AL: "The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer", NATURE MEDICINE, vol. 27, no. 2, 18 January 2021 (2021-01-18), New York, pages 310 - 320, XP093321455, ISSN: 1078-8956, DOI: 10.1038/s41591-020-01168-7 [I] 1-15 [Y] 1-15

DOI:   http://dx.doi.org/10.1038/s41591-020-01168-7
   HAFNER MARC ET AL: "Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity", CELL CHEMICAL BIOLOGY, ELSEVIER, AMSTERDAM, NL, vol. 26, no. 8, 6 June 2019 (2019-06-06), pages 1067, XP085774751, ISSN: 2451-9456, [retrieved on 20190606], DOI: 10.1016/J.CHEMBIOL.2019.05.005 [I] 1-15 [Y] 1-15

DOI:   http://dx.doi.org/10.1016/j.chembiol.2019.05.005
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