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Extract from the Register of European Patents

EP About this file: EP4292593

EP4292593 - PHARMACEUTICAL COMPOSITION FOR PREVENTING CYTOKINE STORM [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  17.11.2023
Database last updated on 31.08.2024
FormerThe international publication has been made
Status updated on  19.08.2022
Most recent event   Tooltip19.04.2024Change: Validation statespublished on 22.05.2024  [2024/21]
19.04.2024Change - extension statespublished on 22.05.2024  [2024/21]
Applicant(s)For all designated states
Kinki University
3-4-1, Kowakae Higashi-Osaka-shi
Osaka 577-8502 / JP
[2023/51]
Inventor(s)01 / NISHIDA Shozo
Higashiosaka City, Osaka 5778502 / JP
02 / TSUBAKI Masanobu
Higashiosaka City, Osaka 5778502 / JP
03 / TAKEDA Tomoya
Higashiosaka City, Osaka 5778502 / JP
04 / TANABE Genzoh
Higashiosaka City, Osaka 5778502 / JP
05 / TAKASHIMA Katsuki
Higashiosaka City, Osaka 5778502 / JP
06 / MORIKAWA Toshio
Higashiosaka City, Osaka 5778502 / JP
 [2023/51]
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstraße 4
80802 München / DE
[2023/51]
Application number, filing date22752864.314.02.2022
[2023/51]
WO2022JP05709
Priority number, dateJP2021002195515.02.2021         Original published format: JP 2021021955
[2023/51]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2022173042
Date:18.08.2022
Language:JA
[2022/33]
Type: A1 Application with search report 
No.:EP4292593
Date:20.12.2023
Language:EN
[2023/51]
Search report(s)International search report - published on:JP18.08.2022
ClassificationIPC:A61K31/352, A23L33/10, A61P37/02, A61P43/00
[2023/51]
CPC:
A23L33/10 (EP); A61K31/7048 (US); A61K31/352 (EP,US);
A61K9/0053 (US); A61P37/06 (US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/51]
TitleGerman:PHARMAZEUTISCHE ZUSAMMENSETZUNG ZUR VERHINDERUNG VON ZYTOKINSTURM[2023/51]
English:PHARMACEUTICAL COMPOSITION FOR PREVENTING CYTOKINE STORM[2023/51]
French:COMPOSITION PHARMACEUTIQUE DESTINÉE À PRÉVENIR UN ORAGE CYTOKINIQUE[2023/51]
Entry into regional phase31.08.2023Translation filed 
31.08.2023National basic fee paid 
31.08.2023Search fee paid 
31.08.2023Designation fee(s) paid 
31.08.2023Examination fee paid 
Examination procedure31.08.2023Examination requested  [2023/51]
Fees paidRenewal fee
31.08.2023Renewal fee patent year 03
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Cited inInternational search[X]WO2020130102  (UNIV KINKI [JP]) [X] 4, 5 * entire text, in particular, claim 5 *;
 [X]WO2020162638  (UNIV KINKI [JP]) [X] 4, 5 * entire text, in particular, claim 5 *;
 [Y]  - Ji-Sun Shin, Young-Su Noh , Dong-Hyun Kim , Young-Wuk Cho , Kyung-Tae Lee, "Mangiferin isolated from the rhizome of Anemarrhena asphodeloides inhibits the LPS-induced nitric oxide and prostagladin E2 via the NF-κB inactivation in inflammatory macrophages.", Natural Product Sciences, (20080101), vol. 14, no. 3, pages 206 - 213, XP055958595 [Y] 1-3 * entire text *
 [Y]  - Qu Shihui; Wang Wenqing; Li Depeng; Li Shumin; Zhang Like; Fu Yunhe; Zhang Naisheng, "Mangiferin inhibits mastitis induced by LPS via suppressing NF-ĸB and NLRP3 signaling pathways", International Immunopharmacology, ELSEVIER, AMSTERDAM, NL, NL , (20161214), vol. 43, doi:10.1016/j.intimp.2016.11.036, ISSN 1567-5769, pages 85 - 90, XP029881743 [Y] 1-3 * entire text *

DOI:   http://dx.doi.org/10.1016/j.intimp.2016.11.036
 [Y]  - Chowdhury Apu, Lu Jihong, Zhang Rumeng, Nabila Jahan, Gao Hang, Wan Zhikang, Adelusi Temitope Isaac, Yin Xiaoxing, Sun Ying, "Mangiferin ameliorates acetaminophen-induced hepatotoxicity through APAP-Cys and JNK modulation", Biomedicine & Pharmacotherapy, ELSEVIER, FR, FR , (20190901), vol. 117, doi:10.1016/j.biopha.2019.109097, ISSN 0753-3322, page 109097, XP055958598 [Y] 1-3 * entire text *

DOI:   http://dx.doi.org/10.1016/j.biopha.2019.109097
 [Y]  - Satoshi Shuto, "4) Prodrugs", Molecular theory of organic pharmaceuticals, JP, Kyoto Hirokawa Shoten, (20120825), pages 169 - 171, ISBN 978-4-901789-81-3, XP009539019 [Y] 1-3 * entire text * [Y] 1-3
 [Y]  - Wilz, S. W., "A clinical trial of IL-15 and IL-21 combination therapy for COVID-19 is warranted. ", Cytokine & Growth Factor Reviews, Elsevier Ltd, GB, GB , (20200801), vol. 58, doi:10.1016/j.cytogfr.2020.06.008, ISSN 1359-6101, pages 49 - 50, XP055958605 [Y] 1 * entire text *

DOI:   http://dx.doi.org/10.1016/j.cytogfr.2020.06.008
 [Y]  - Gu Tingxuan, Zhao Simin, Jin Guoguo, Song Mengqiu, Zhi Yafei, Zhao Ran, Ma Fayang, Zheng Yaqiu, Wang Keke, Liu Hui, Xin Mingxia, Han Wei, Li Xiang, Dong Christopher D., Liu Kangdong, Dong Zigang, "Cytokine Signature Induced by SARS-CoV-2 Spike Protein in a Mouse Model", Frontiers in Immunology, (20210128), vol. 11, doi:10.3389/fimmu.2020.621441, XP055877307 [Y] 1 * entire text *

DOI:   http://dx.doi.org/10.3389/fimmu.2020.621441
 [Y]  - Convertino Irma, Tuccori Marco, Ferraro Sara, Valdiserra Giulia, Cappello Emiliano, Focosi Daniele, Blandizzi Corrado, "Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients", Critical Care, (20201201), vol. 24, no. 1, doi:10.1186/s13054-020-03020-3, XP055879485 [Y] 1 * entire text *

DOI:   http://dx.doi.org/10.1186/s13054-020-03020-3
by applicantJP2012020953
 WO2016104436
    - HU LWU WCHAI XLUO JWU Q, Bioorg. Med. Chem. Lett, (20110000), vol. 21, pages 4013 - 4015
    - CAS, no. 3542-72-1
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