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Extract from the Register of European Patents

EP About this file: EP4223319

EP4223319 - METHOD AND MOLECULES [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  12.07.2024
Database last updated on 14.09.2024
FormerThe application has been published
Status updated on  07.07.2023
Most recent event   Tooltip12.07.2024The date on which the examining division becomes responsible, has been established 
12.07.2024Request for examination filedpublished on 14.08.2024  [2024/33]
12.07.2024Change - designated statespublished on 14.08.2024  [2024/33]
Applicant(s)For all designated states
MedImmune, LLC
One MedImmune Way
Gaithersburg, MD 20878 / US
For all designated states
The Regents of the University of California
1111 Franklin Street 12th Floor
Oakland CA 94607-5200 / US
[2023/32]
Inventor(s)01 / CHRISTIE, Ronald James
Gaithersburg, 20878 / US
02 / GAO, Changshou
Gaithersburg, 20878 / US
03 / ST. AMANT, Andre Henri
Oakland, 94607-5200 / US
04 / DE ALANIZ, Javier Read
Oakland, 94607-5200 / US
 [2023/32]
Representative(s)AstraZeneca Intellectual Property
Eastbrook House
Shaftesbury Road
Cambridge CB2 8BF / GB
[2023/32]
Application number, filing date23166601.725.05.2018
[2023/32]
Priority number, dateUS201762511415P26.05.2017         Original published format: US 201762511415 P
[2023/32]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP4223319
Date:09.08.2023
Language:EN
[2023/32]
Type: A3 Search report 
No.:EP4223319
Date:10.01.2024
Language:EN
[2024/02]
Search report(s)(Supplementary) European search report - dispatched on:EP13.12.2023
ClassificationIPC:A61K47/68, C07D249/12, C07K1/13, C07K1/107, C07C233/52, C07C247/10, C07C247/12, C07C271/22, C07D307/58, A61P35/00, A61K47/69, A61P29/00, C07C233/48
[2023/32]
CPC:
C07D307/58 (EP,EA,KR); A61K47/6811 (EP,EA,KR,US); A61K47/6889 (EA,US);
A61K47/6923 (EP,EA,KR,US); A61P29/00 (EP,EA,KR); A61P35/00 (EP,EA,KR);
C07C233/48 (EP,EA,KR); C07C233/52 (EP,EA,KR); C07C247/10 (EP,EA,KR);
C07C247/12 (EP,EA,KR); C07C271/22 (EP,EA,KR,US); C07D207/46 (EA,US);
C07K1/1077 (EP); C07K1/13 (EP,EA,KR); C07C2601/10 (EP,EA,KR,US);
C07C2602/50 (EP,EA,KR,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2024/33]
Former [2023/32]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:VERFAHREN UND MOLEKÜLE[2023/32]
English:METHOD AND MOLECULES[2023/32]
French:PROCEDE ET MOLECULES[2023/32]
Examination procedure01.07.2024Amendment by applicant (claims and/or description)
10.07.2024Examination requested  [2024/33]
10.07.2024Date on which the examining division has become responsible
Parent application(s)   TooltipEP18805779.8  / EP3630732
Fees paidRenewal fee
04.08.2023Renewal fee patent year 03
04.08.2023Renewal fee patent year 04
04.08.2023Renewal fee patent year 05
04.08.2023Renewal fee patent year 06
31.05.2024Renewal fee patent year 07
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]EP1548109  (JAPAN SCIENCE & TECH AGENCY [JP]) [X] 1 * compounds 23,29 *;
 [X]WO2013171485  (MEDICAL RES COUNCIL [GB]) [X] 1,2,14 * figure 1 *;
 [XI]  - KURT HOOGEWIJS ET AL, "Exploiting furan's versatile reactivity in reversible and irreversible orthogonal peptide labeling", CHEMICAL COMMUNICATIONS, (20130101), vol. 49, no. 28, doi:10.1039/c3cc40588e, ISSN 1359-7345, page 2927, XP055179073 [X] 1,14 * figure 1 * [I] 2-11

DOI:   http://dx.doi.org/10.1039/c3cc40588e
 [XA]  - TILMAN PLASS ET AL, "Amino Acids for Diels-Alder Reactions in Living Cells", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, VERLAG CHEMIE, HOBOKEN, USA, (20120330), vol. 51, no. 17, doi:10.1002/ANIE.201108231, ISSN 1433-7851, pages 4166 - 4170, XP072080583 [X] 1,2,14 * scheme 1a * [A] 3-13

DOI:   http://dx.doi.org/10.1002/anie.201108231
 [X]  - MORITZ J SCHMIDT ET AL, "Red-Light-Controlled Protein-RNA Crosslinking with a Genetically Encoded Furan", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, VERLAG CHEMIE, HOBOKEN, USA, (20130319), vol. 52, no. 17, doi:10.1002/ANIE.201300754, ISSN 1433-7851, pages 4690 - 4693, XP072076681 [X] 1-11,14 * compound 1 *

DOI:   http://dx.doi.org/10.1002/anie.201300754
 [XI]  - DE ARAúJO ALINE DANTAS ET AL, "Diels-Alder Ligation and Surface Immobilization of Proteins", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, Hoboken, USA, (20060101), vol. 45, no. 2, doi:10.1002/anie.200502266, ISSN 1433-7851, pages 296 - 301, XP055777294 [X] 1-3,14 * compound 11 * [I] 4-11

DOI:   http://dx.doi.org/10.1002/anie.200502266
 [X]  - BALDWIN J.E ET AL, "Use of L-aspartic acid [beta]-semialdehyde in the synthesis of more complex non protein amino acids", TETRAHEDRON LETTERS, Amsterdam , NL, (19870101), vol. 28, no. 31, doi:10.1016/S0040-4039(00)95547-3, ISSN 0040-4039, pages 3605 - 3608, XP093061845 [X] 1 * compounds 9,11,12 *

DOI:   http://dx.doi.org/10.1016/S0040-4039(00)95547-3
 [X]  - EMINE KAYA ET AL, "A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-Free Click Reaction", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, VERLAG CHEMIE, HOBOKEN, USA, (20120321), vol. 51, no. 18, doi:10.1002/ANIE.201109252, ISSN 1433-7851, pages 4466 - 4469, XP072073535 [X] 1,2,14 * scheme 1a *

DOI:   http://dx.doi.org/10.1002/anie.201109252
 [X]  - ALINE DANTAS DE ARAÚJO ET AL, "Diels-Alder Ligation of Peptides and Proteins", CHEMISTRY - A EUROPEAN JOURNAL, JOHN WILEY & SONS, INC, DE, (20060628), vol. 12, no. 23, doi:10.1002/CHEM.200600148, ISSN 0947-6539, pages 6095 - 6109, XP071825428 [X] 1,2,14 * scheme 3 *

DOI:   http://dx.doi.org/10.1002/chem.200600148
by applicantUS3896111
 US4137230
 US4151042
 US4248870
 US4256746
 US4260608
 US4265814
 US4294757
 US4307016
 US4308268
 US4308269
 US4309428
 US4313946
 US4315929
 US4317821
 US4322348
 US4331598
 US4361650
 US4362663
 US4364866
 US4371533
 US4424219
 US4450254
 EP0425235
 US5208020
 WO9321232
 US5416064
 WO9520401
 WO9627011
 US5635483
 US5663149
 US5712374
 US5714586
 US5739116
 WO9820734
 US5767285
 US5770701
 US5770710
 US5773001
 US5780588
 US5789208
 US5830912
 US5877296
 WO0012507
 US6335163
 WO0220565
 WO0248189
 WO02088172
 US2003082630
 US2003157561
 WO2004009618
 WO2005040170
 WO2005056764
 WO2005085251
 WO2005110423
 EP1641818
 WO2007024715
 WO2007039752
 US2008139791
 WO2009018386
 WO2009058379
 WO2009080251
 US7612062
 US7776814
 WO2011130324
 WO2012019123
 WO2013006544
 WO2013070565
 WO2013096291
 US2015005481
 WO2015019192
    - Protein Eng. Des. Sel., (20050000), vol. 18, pages 435 - 444
    - Protein Eng. Des. Sel., (20040000), vol. 17, pages 455 - 462
    - Nature Biotechnology, (20050000), vol. 23, no. 12, pages 1556 - 1561
    - Expert Opinion on Investigational Drugs, (20070600), vol. 16, no. 6, pages 909 - 917
    - J. Mol. Biol., (20030000), vol. 332, pages 489 - 503
    - Biol, (20070000), page 369
    - WOYKE et al., Antimicrob. Agents and Chemother, (20010000), vol. 45, pages 3580 - 3584
    - LIU et al., Proc. Natl. Acad. Sci. USA, (19960000), vol. 93, pages 8618 - 8623
    - CHARI et al., Cancer Research, (19920000), vol. 52, pages 127 - 131
    - HINMAN et al., Cancer Research, (19930000), vol. 53, pages 3336 - 3342
    - LODE et al., Cancer Research, (19980000), vol. 58, pages 2925 - 2928
    - SASSE et al., J. Antibiot., (20000000), vol. 53, pages 879 - 885
    - STEINMETZ et al., Chem. Int. Ed., (20040000), vol. 43, pages 4888 - 4892
    - KHALIL et al., ChemBioChem, (20060000), vol. 7, pages 678 - 683
    - KAUR et al., Biochem. J., (20060000), vol. 396, pages 235 - 242
    - DOMLING et al., Mol. Diversity, (20050000), vol. 9, pages 141 - 147
    - LEDFORD, B. E.CARREIRA, E. M., "Total Synthesis of (+)-Trehazolin: Optically Active Spirocycloheptadienes as Useful Precursors for the Synthesis of Amino Cyclopentitols", Journal of the American Chemical Society, (19950000), vol. 117, doi:10.1021/ja00152a026, pages 11811 - 11812, XP001204125

DOI:   http://dx.doi.org/10.1021/ja00152a026
    - PETERSON, G. I.CHURCH, D. C.YAKELIS, N. A.BOYDSTON, A. J., "1,2-oxazine linker as a thermal trigger for self-immolative polymers", Polymer, (20140000), vol. 55, doi:10.1016/j.polymer.2014.09.048, pages 5980 - 5985, XP029092601

DOI:   http://dx.doi.org/10.1016/j.polymer.2014.09.048
    - FOSTER, R. W.BENHAMOU, L.PORTER, M. J.BUCAR, D.-K.HAILES, H. C.TAME, C. J.SHEPPARD, T. D., "Irreversible endo-Selective Diels-Alder Reactions of Substituted Alkoxyfurans: A General Synthesis of endo-Cantharimides", Chemistry (Weinheim an Der Bergstrasse, Germany, (20150000), vol. 21, pages 6107 - 6114
    - HONZICEK, J.MUKHOPADHYAY, A.SANTOS-SILVA, T.ROMAO, M. J.ROMAO, C. C., "Ring-Functionalized Molybdenocene Complexes", Organometallics, (20090000), vol. 28, pages 2871 - 2879
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.