Extract from the Register of European Patents

EP About this file: EP4516782

EP4516782 - CRYSTAL FORM OF BLARCAMESINE HYDROCHLORIDE, METHOD FOR PREPARING SAME, AND USE THEREOF [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  30.01.2026
Database last updated on 09.04.2026
FormerRequest for examination was made
Status updated on  31.01.2025
FormerThe international publication has been made
Status updated on  03.11.2023
Most recent event   Tooltip18.03.2026New entry: Renewal fee paid 
Applicant(s)For all designated states
Crystal Pharmaceutical (Suzhou) Co., Ltd.
B4-301 Biobay
218 Xinghu Street
Suzhou Industrial Park
Suzhou, Jiangsu 215123 / CN
For all designated states
Moehs Iberica SL
Pol Ind Rubi Sud
César Martinell i Brunet 12a
08191 Rubi, Barcelona / ES
[2025/10]
Inventor(s)01 / ZHANG, Yuxing
Suzhou, Jiangsu 215123 / CN
02 / ZHU, Hongyan
Suzhou, Jiangsu 215123 / CN
03 / MENG, Liping
Suzhou, Jiangsu 215123 / CN
 [2025/10]
Representative(s)dompatent
Partnerschaft von
Patentanwälten und Rechtsanwälten mbB
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
[N/P]
Former [2025/10]dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
Application number, filing date23795565.327.04.2023
[2025/10]
WO2023CN91293
Priority number, dateCN20221047287329.04.2022         Original published format: CN202210472873
CN20221047399329.04.2022         Original published format: CN202210473993
CN20221062390002.06.2022         Original published format: CN202210623900
[2025/10]
Filing languageZH
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2023208133
Date:02.11.2023
Language:ZH
[2023/44]
Type: A1 Application with search report 
No.:EP4516782
Date:05.03.2025
Language:EN
[2025/10]
Search report(s)International search report - published on:CN02.11.2023
(Supplementary) European search report - dispatched on:EP13.05.2025
ClassificationIPC:C07D307/14, A61K31/341, A61P25/28
[2025/10]
CPC:
C07D307/14 (EP,US); A61K31/341 (EP,US); A61K9/2013 (EP,US);
A61K9/2027 (EP,US); A61K9/2054 (EP,US); A61P25/28 (EP);
C07C59/245 (EP,US); C07C59/255 (EP,US); C07C59/265 (EP,US);
C07B2200/13 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   ME,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2025/10]
TitleGerman:KRISTALLFORM VON BLARCAMESINHYDROCHLORID, VERFAHREN ZU IHRER HERSTELLUNG UND VERWENDUNG DAVON[2025/10]
English:CRYSTAL FORM OF BLARCAMESINE HYDROCHLORIDE, METHOD FOR PREPARING SAME, AND USE THEREOF[2025/10]
French:FORME CRISTALLINE DE CHLORHYDRATE DE BLARCAMÉSINE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION[2025/10]
Entry into regional phase28.11.2024Translation filed 
28.11.2024National basic fee paid 
28.11.2024Search fee paid 
28.11.2024Designation fee(s) paid 
28.11.2024Examination fee paid 
Examination procedure28.11.2024Examination requested  [2025/10]
05.11.2025Amendment by applicant (claims and/or description)
05.11.2025Date on which the examining division has become responsible
02.02.2026Despatch of a communication from the examining division (Time limit: M04)
Fees paidRenewal fee
25.02.2025Renewal fee patent year 03
17.03.2026Renewal fee patent year 04
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Documents cited:Search[DI] WO2021158586  (TEVA PHARMACEUTICALS INT GMBH et al.) [DI] 1-14 * Whole document, particularly example 10, page 35; page 35; example 10 *
 [DA] WO2019200345  (ANAVEX LIFE SCIENCES CORP et al.) [DA] 1-14 * whole document, particularly pages 12-20, crystal forms I-VII.; page 12 - page 20 *
 [A]   MINO R CAIRA ED - MONTCHAMP JEAN-LUC: "CRYSTALLINE POLYMORPHISM OF ORGANIC COMPOUNDS", TOPICS IN CURRENT CHEMISTRY; [TOPICS IN CURRENT CHEMISTRY], SPRINGER, BERLIN, DE, vol. 198, 1 January 1998 (1998-01-01), pages 163 - 208, XP001156954, ISSN: 0340-1022, [retrieved on 19990226], DOI: 10.1007/3-540-69178-2_5 [A] 1-14 * page 165 - page 180 *

DOI:   http://dx.doi.org/10.1007/3-540-69178-2_5
International search[X] WO2021158586  (TEVA PHARMACEUTICALS INT GMBH et al.) [X] 1-22 * description, page 35, paragraph [00201], and description, figure 13 *
 [A] CN108026059  (ANAVEX LIFE SCIENCES CORP et al.) [A] 1-22 * entire document *
 [A] CN112105349  (ANAVEX LIFE SCIENCES CORP et al.) [A] 1-22 * entire document *
by applicantWO2021158586
 WO2017013498
 WO2019200345
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