Extract from the Register of European Patents

EP About this file: EP4608862

EP4608862 - COMPOSITIONS OF ANTI-INTERLEUKIN 12/INTERLEUKIN 23 ANTIBODY [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  01.08.2025
Database last updated on 11.04.2026
FormerThe international publication has been made
Status updated on  04.05.2024
Formerunknown
Status updated on  06.12.2023
Most recent event   Tooltip09.01.2026Change: Validation statespublished on 11.02.2026  [2026/07]
09.01.2026Change - extension statespublished on 11.02.2026  [2026/07]
Applicant(s)For all designated states
Amgen Inc.
One Amgen Center Drive
Thousand Oaks, CA 91320-1799 / US
[2025/36]
Inventor(s)01 / BRIDGEWATER, Juma
Thousand Oaks, California 91320-1799 / US
02 / PRABHU, Siddharth
Thousand Oaks, California 91320-1799 / US
03 / TOKUDA, Joshua
Thousand Oaks, California 91320-1799 / US
04 / XIANG, Dong
Thousand Oaks, California 91320-1799 / US
05 / JOUBERT, Marisa
Thousand Oaks, California 91320-1799 / US
06 / LIU, Qian
Thousand Oaks, California 91320-1799 / US
07 / POLOZOVA, Alla
Thousand Oaks, California 91320-1799 / US
08 / ELBARADEI, Ahmed
Thousand Oaks, California 91320-1799 / US
 [2025/36]
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstraße 4
80802 München / DE
[2025/36]
Application number, filing date23814019.827.10.2023
[2025/36]
WO2023US78032
Priority number, dateUS202263381459P28.10.2022         Original published format: US 202263381459 P
US202363583438P18.09.2023         Original published format: US 202363583438 P
US202363591990P20.10.2023         Original published format: US 202363591990 P
[2025/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2024092203
Date:02.05.2024
Language:EN
[2024/18]
Type: A1 Application with search report 
No.:EP4608862
Date:03.09.2025
Language:EN
The application published by WIPO in one of the EPO official languages on 02.05.2024 takes the place of the publication of the European patent application.
[2025/36]
Search report(s)International search report - published on:EP02.05.2024
ClassificationIPC:C07K16/24
[2025/36]
CPC:
C07K16/244 (EP); G01N33/6848 (EP); G01N33/6869 (EP);
C07K2317/41 (EP); C07K2317/565 (EP); C07K2317/567 (EP);
C07K2317/76 (EP); C07K2317/94 (EP); G01N2333/5434 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   ME,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2025/36]
TitleGerman:ZUSAMMENSETZUNGEN VON ANTI-INTERLEUKIN 12/INTERLEUKIN 23-ANTIKÖRPERN[2025/36]
English:COMPOSITIONS OF ANTI-INTERLEUKIN 12/INTERLEUKIN 23 ANTIBODY[2025/36]
French:COMPOSITIONS D'ANTICORPS ANTI-INTERLEUKINE 12/INTERLEUKINE 23[2025/36]
Entry into regional phase13.05.2025National basic fee paid 
13.05.2025Designation fee(s) paid 
13.05.2025Examination fee paid 
Examination procedure13.05.2025Examination requested  [2025/36]
13.05.2025Date on which the examining division has become responsible
28.11.2025Amendment by applicant (claims and/or description)
Fees paidRenewal fee
22.10.2025Renewal fee patent year 03
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Cited inInternational search[IY] US2020291107  (BARNTHOUSE KRISTOPHER et al.)
 [IY] CN114395041  (GANLI PHARMACY CO LTD et al.)
 [IY] WO2020142275  (MOMENTA PHARMACEUTICALS INC et al.)
 [Y] US2019321752  (RANDOLPH PAUL et al.)
by applicantWO2022132982
 US2021063641
   COBB, BA: "The history of IgG glycosylation and where we are now", GLYCOBIOLOGY, vol. 30, no. 4, 2020, pages 202 - 213
   IMMUNOL LETT, vol. 111, 2007, pages 66 - 8
   BECK ALIU H: "Macro- and micro-heterogeneity of natural and recombinant IgG antibodies", ANTIBODIES, vol. 8, no. 1, 2019, pages 18
   SHAH B ET AL.: "J Pharm Sci", 2022, PRESS, article "Heavy-chain C-terminal amidation in therapeutic IgG does not pose a safety concern"
   TSUBAKI M ET AL.: "C-terminal modification of monoclonal antibody drugs: amidated species as a general product-related substance", INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, vol. 52, 2013, pages 139 - 47, XP055120412, DOI: 10.1016/j.ijbiomac.2012.09.016

DOI:   http://dx.doi.org/10.1016/j.ijbiomac.2012.09.016
   "REMINGTON'S PHARMACEUTICAL SCIENCES", 1990, MACK PUBLISHING COMPANY
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