Extract from the Register of European Patents

EP About this file: EP4652191

EP4652191 - IL-18 VARIANT POLYPEPTIDES [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  24.10.2025
Database last updated on 08.04.2026
FormerThe international publication has been made
Status updated on  27.07.2024
Most recent event   Tooltip20.03.2026Change: Validation statespublished on 22.04.2026 [2026/17]
20.03.2026Change - extension statespublished on 22.04.2026 [2026/17]
Applicant(s)For all designated states
TJ Biopharma (Shanghai) Co., Ltd.
Rm 802, 8F, 1Bld., West Tower
88 Shangke Rd.
Pudong New Area
Shanghai 201210 / CN
[2025/48]
Inventor(s)01 / QIANG, Min
Shanghai 201210 / CN
02 / CHEN, Xi
Shanghai 201210 / CN
03 / WANG, Zhengyi
Shanghai 201210 / CN
04 / ZENG, Hui
Shanghai 201210 / CN
05 / ZHENG, Xin
Beijing 100000 / CN
06 / ZHANG, Fei
Beijing 100000 / CN
07 / YUAN, Puwei
Beijing 100000 / CN
08 / LIU, Fan
Beijing 100000 / CN
 [2025/48]
Representative(s)CMS Cameron McKenna Nabarro Olswang LLP
Cannon Place
78 Cannon Street
London EC4N 6AF / GB
[2025/48]
Application number, filing date24744355.918.01.2024
[2025/48]
WO2024CN73014
Priority number, dateWO2023CN7288618.01.2023         Original published format: PCT/CN2023/072886
WO2023CN11719706.09.2023         Original published format: PCT/CN2023/117197
[2025/48]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2024153183
Date:25.07.2024
Language:EN
[2024/30]
Type: A1 Application with search report 
No.:EP4652191
Date:26.11.2025
Language:EN
The application published by WIPO in one of the EPO official languages on 25.07.2024 takes the place of the publication of the European patent application.
[2025/48]
Search report(s)International search report - published on:CN25.07.2024
ClassificationIPC:C07K14/54, C12N15/24, A61K38/20
[2025/48]
CPC:
C07K14/54 (EP); A61K38/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   ME,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2025/48]
TitleGerman:IL-18-POLYPEPTIDVARIANTEN[2025/48]
English:IL-18 VARIANT POLYPEPTIDES[2025/48]
French:POLYPEPTIDES VARIANTS D'IL-18[2025/48]
Entry into regional phase12.08.2025National basic fee paid 
12.08.2025Search fee paid 
12.08.2025Designation fee(s) paid 
12.08.2025Examination fee paid 
Examination procedure12.08.2025Examination requested  [2025/48]
Fees paidRenewal fee
31.12.2025Renewal fee patent year 03
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Cited inInternational search[PX] US2023357342  (PATTABIRAMAN VIJAYA RAGHAVAN et al.) [PX] 19, 30-51 * the whole document, especially claims and the abstract *
 [XA]   SAETANG JIRAKRIT, ROONGSAWANG NIRAN, SANGKHATHAT SURASAK, VORAVUTHIKUNCHAI SUPAYANG PIYAWAN, SANGKAEW NATNAREE, PROMPAT NAPAT, SRI: "Surface cysteine to serine substitutions in IL-18 reduce aggregation and enhance activity", PEERJ, vol. 10, 5 July 2022 (2022-07-05), pages e13626, XP093039619, DOI: 10.7717/peerj.13626 [X] 19, 30-51 * the whole document, especially the abstract * [A] 1-18, 20-29

DOI:   http://dx.doi.org/10.7717/peerj.13626
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