Extract from the Register of European Patents

EP About this file: EP0018794

EP0018794 - Monoclonal antibody to human helper T cells, method of preparing it, hybrid cell line producing it, its diagnostic and therapeutic uses and diagnostic and therapeutic compositions comprising it [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  02.08.1991
Database last updated on 28.03.2026
Most recent event   Tooltip17.04.2015Change - lapse in a contracting state
State(s) deleted from list of lapses: CH, LI
published on 20.05.2015  [2015/21]
Applicant(s)For all designated states
ORTHO PHARMACEUTICAL CORPORATION
U.S. Route 202 P.O. Box 300 Raritan
New Jersey 08869-0602 / US
[N/P]
Former [1980/23]For all designated states
ORTHO PHARMACEUTICAL CORPORATION
U.S. Route 202 P.O. Box 300
Raritan New Jersey 08869-0602 / US
Inventor(s)01 / Kung, Patrick Chung-Shu
1096 Rector Road
Bridgewater New Jersey / US
02 / Goldstein, Gideon
30 Dorison Drive
Short Hills New Jersey / US
[1980/23]
Representative(s)Jones, Alan John, et al
CARPMAELS & RANSFORD 43 Bloomsbury Square
London, WC1A 2RA / GB
[N/P]
Former [1980/23]Jones, Alan John, et al
CARPMAELS & RANSFORD 43 Bloomsbury Square
London, WC1A 2RA / GB
Application number, filing date80301356.425.04.1980
[1980/23]
Priority number, dateUS1979003363926.04.1979         Original published format: US 33639
[1980/23]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0018794
Date:12.11.1980
Language:EN
[1980/23]
Type: A3 Search report 
No.:EP0018794
Date:07.01.1981
Language:EN
[1981/01]
Type: B1 Patent specification 
No.:EP0018794
Date:24.07.1985
Language:EN
[1985/30]
Search report(s)(Supplementary) European search report - dispatched on:EP29.10.1980
ClassificationIPC:C12P1/00, C12N5/00, C12N15/00, A61K39/395, G01N33/50
[1985/30]
CPC:
C07K16/3061 (EP,US); A61P37/00 (EP); C07K16/2812 (EP,US);
A61K38/00 (EP,US); Y10S435/966 (EP,US); Y10S530/808 (EP,US)
Former IPC [1980/23]C12P1/00, C12N5/00, C12N15/00, A61K39/395, G01N33/54, // C12R1/91
Designated contracting statesAT,   BE,   CH,   DE,   FR,   GB,   IT,   LI,   NL,   SE [1980/23]
TitleGerman:Monoklonaler Antikörper gegen menschliche Helfer-T-Zellen, Verfahren zu seiner Herstellung, ihn produzierende Hybridzellinie, seine diagnostischen und therapeutischen Verwendungen und diesen Antikörper enthaltende diagnostische und therapeutische Zusammensetzungen[1980/23]
English:Monoclonal antibody to human helper T cells, method of preparing it, hybrid cell line producing it, its diagnostic and therapeutic uses and diagnostic and therapeutic compositions comprising it[1980/23]
French:Anticorps monoclonal contre les cellules-T-promoteur humaines, procédé pour sa préparation, lignée cellulaire hybride le produisant, ses applications diagnostiques et thérapeutiques et compositions diagnostiques et thérapeutiques le contenant[1980/23]
Biological materialThis application mentions deposited biological material, check the file for details
Examination procedure16.06.1981Examination requested  [1981/36]
11.11.1981Despatch of a communication from the examining division (Time limit: M04)
10.03.1982Reply to a communication from the examining division
17.05.1984Despatch of communication of intention to grant (Approval: )
23.07.1984Communication of intention to grant the patent
07.08.1984Fee for grant paid
07.08.1984Fee for publishing/printing paid
Opposition(s)Opponent(s)01  10.04.1986  26.06.1986  ADMISSIBLE
Biotest-Serum-Institut GmbH
Flughafenstrasse 4
D-60528 Frankfurt / DE
Opponent's representative
Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
 02  18.04.1986  26.06.1986  ADMISSIBLE
Behringwerke Aktiengesellschaft
Postfach 11 40
D-35001 Marburg / DE
 03  23.04.1986  04.08.1986  ADMISSIBLE
Becton, Dickinson and Company
Mack Centre Drive
Paramus, New Jersey 07652 / US
Opponent's representative
Ruffles, Graham Keith
Marks & Clerk LLP 62-68 Hills Road Cambridge
CB2 1LA / GB
 04  23.04.1986  04.08.1986  ADMISSIBLE
SANDOZ AG Patent- und Markenabteilung
Lichtstrasse 35
CH-4002 Basel / CH
 05  23.04.1986  04.08.1986  ADMISSIBLE
Boehringer Mannheim GmbH Patentabteilung
Sandhofer Strasse 116
D-68298 Mannheim / DE
Opponent's representative
Weickmann, Heinrich, et al, et al
Weickmann & Weickmann Patentanwälte Postfach 86 08 20
81635 München / DE
 [N/P]
Former [2008/35]
Opponent(s)01  10.04.1986  26.06.1986  ADMISSIBLE
Biotest-Serum-Institut GmbH
Flughafenstrasse 4
D-60528 Frankfurt / DE
Opponent's representative
Vossius & Partner
Postfach 86 07 67
81634 München / DE
 02  18.04.1986  26.06.1986  ADMISSIBLE
Behringwerke Aktiengesellschaft
Postfach 11 40
D-35001 Marburg / DE
 03  23.04.1986  04.08.1986  ADMISSIBLE
Becton, Dickinson and Company
Mack Centre Drive
Paramus, New Jersey 07652 / US
Opponent's representative
Ruffles, Graham Keith
MARKS & CLERK, 57-60 Lincoln's Inn Fields
London WC2A 3LS / GB
 04  23.04.1986  04.08.1986  ADMISSIBLE
SANDOZ AG Patent- und Markenabteilung
Lichtstrasse 35
CH-4002 Basel / CH
 05  23.04.1986  04.08.1986  ADMISSIBLE
Boehringer Mannheim GmbH Patentabteilung
Sandhofer Strasse 116
D-68298 Mannheim / DE
Opponent's representative
Weickmann, Heinrich, Dipl.-Ing., et al, et al
Patentanwälte H. Weickmann, Dr. K. Fincke F.A. Weickmann, B. Huber Dr. H. Liska, Dr. J. Prechtel, Dr. B. Böhm Postfach 86 08 20
D-81635 München / DE
Former [1986/25]
Opponent(s)01  10.04.1986  26.06.1986  ADMISSIBLE
Biotest-Serum-Institut GmbH
Flughafenstrasse 4
D-60528 Frankfurt / DE
Opponent's representative
VOSSIUS & PARTNER
Siebertstrasse 4 P.O. Box 86 07 67
D-8000 München 86 / DE
 02  18.04.1986  26.06.1986  ADMISSIBLE
Behringwerke Aktiengesellschaft
Postfach 11 40
D-35001 Marburg / DE
 03  23.04.1986  04.08.1986  ADMISSIBLE
Becton, Dickinson and Company
Mack Centre Drive
Paramus, New Jersey 07652 / US
Opponent's representative
Ruffles, Graham Keith
MARKS & CLERK, 57-60 Lincoln's Inn Fields
London WC2A 3LS / GB
 04  23.04.1986  04.08.1986  ADMISSIBLE
SANDOZ AG Patent- und Markenabteilung
Lichtstrasse 35
CH-4002 Basel / CH
 05  23.04.1986  04.08.1986  ADMISSIBLE
Boehringer Mannheim GmbH Patentabteilung
Sandhofer Strasse 116
D-68298 Mannheim / DE
Opponent's representative
Weickmann, Heinrich, Dipl.-Ing., et al, et al
Patentanwälte H. Weickmann, Dr. K. Fincke F.A. Weickmann, B. Huber Dr. H. Liska, Dr. J. Prechtel, Dr. B. Böhm Postfach 86 08 20
D-81635 München / DE
Former [1986/23]
Opponent(s)01  10.04.1986  26.06.1986  ADMISSIBLE
Biotest-Serum-Institut GmbH
Flughafenstrasse 4
D-60528 Frankfurt / DE
Opponent's representative
VOSSIUS & PARTNER
Siebertstrasse 4 P.O. Box 86 07 67
D-8000 München 86 / DE
05.08.1986Invitation to proprietor to file observations on the notice of opposition
01.10.1987Reply of patent proprietor to notice(s) of opposition
04.07.1988Despatch of a communication from the opposition division (Time limit: M06)
09.01.1991Despatch of communication that the patent will be revoked
30.07.1991Legal effect of revocation of patent [1991/38]
Appeal following opposition31.07.1989Appeal received No.  T0495/89
15.11.1989Statement of grounds filed
09.01.1991Result of appeal procedure: revocation of the patent
09.01.1991Date of oral proceedings
Fees paidRenewal fee
13.04.1982Renewal fee patent year 03
15.04.1983Renewal fee patent year 04
11.04.1984Renewal fee patent year 05
11.04.1985Renewal fee patent year 06
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Lapses during opposition  Tooltipdeleted
[2015/21]
Former [1992/06]CH24.07.1985
LI24.07.1985
Documents cited:Search  NATURE, Vol. 273, 22nd June 1978, M.M. TRUCCO et al. "Monoclonal antibodies against human lymphocyte antigens", pages 666-668. * Whole article *
   NATURE, Vol. 256, 7th August, 1975, G. KOHLER et al. "Continuous cultures of fusedcells secreting antibody of predefined specificity" pages 495-497. * Whole article *
   CHEMICAL & ENGINEERING NEWS, Vol. 57, No. 1, 1st January, 1979 J.L. FOX "Antibody reagents revolutionizing immunology", pages 15-17. * Whole article *
   CHEMICAL ABSTRACTS, Vol. 89, No. 15, 9th October, 1978, page 435, Abstract 127545z, Columbus, Ohio, USA TROWBRIDGE, I.S. "Interspecies spleen-myeloma hybrid producing monoclonal antibodies against mouse lymphocyte surface glycoprotein, T200" & J. Exp. Med. 1978, 148(1), 313-23. * Whole Abstract *
   CHEMICAL ABSTRACTS, Vol. 88, No. 3, 16th January, 1978, page 432, Abstract 20373u Columbus, Ohio, USA WILLIAMS A.F. "Analysis of cell surfaces by xenogeneic myelomahybrid antibodies: differentiation antigens of rat lymphocytes". & Cell (Cambridge, Mass.) 1977, 12(3), 663-73. * Whole Abstract *
   CHEMICAL ABSTRACTS, Vol. 90, No. 1, 1st January, 1979, page 412, Abstract 4241k Columbus, Ohio, USA HAEMMERLING G.J. et al. "Monoclonal antibodies against murine cell surface antigens: anti-H-2, anti-Ia and anti-T cell antibodies", & Curr. Top. Microbiol. Immunol. 1978, 81 (Lymphocyte Hybridomas), 100-6. * Whole Abstract *
   UNLISTED DRUGS, Vol. 32, No. 5, May 1980, page 65, & Fed. Proc. 39, 3463 Abs, 1st March 1980. * Left-hand column, point c, reference MT-1 *
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