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Extract from the Register of European Patents

EP About this file: EP0110955

EP0110955 - BRAIN-SPECIFIC DRUG DELIVERY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  28.06.1996
Database last updated on 11.09.2024
Most recent event   Tooltip28.12.2002Lapse of the patent in a contracting state
New state(s): NL
published on 12.02.2003  [2003/07]
Applicant(s)For all designated states
University of Florida
223 Grinter Hall Gainesville
Florida 32611-2037 / US
[N/P]
Former [1995/10]For all designated states
UNIVERSITY OF FLORIDA
223 Grinter Hall
Gainesville, Florida 32611-2037 / US
Former [1984/25]For all designated states
UNIVERSITY OF FLORIDA
207 Tigert Hall
Gainesville, Florida 32611 / US
Inventor(s)01 / BODOR, Nicholas S.
7211 South West 97th Lane
Gainesville, FL 32608 / US
[1984/25]
Representative(s)Pendlebury, Anthony, et al
PAGE, WHITE & FARRER 54 Doughty Street
London WC1N 2LS / GB
[1984/25]
Application number, filing date83902034.412.05.1983
[1984/25]
WO1983US00725
Priority number, dateUS1982037931618.05.1982         Original published format: US 379316
US1983046154327.01.1983         Original published format: US 461543
US1983047549315.03.1983         Original published format: US 475493
[1984/25]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO8303968
Date:24.11.1983
[1983/27]
Type: A1 Application with search report 
No.:EP0110955
Date:20.06.1984
Language:EN
The application published by WIPO in one of the EPO official languages on 24.11.1983 takes the place of the publication of the European patent application.
[1984/25]
Type: B1 Patent specification 
No.:EP0110955
Date:23.08.1995
Language:EN
[1995/34]
Search report(s)
ClassificationIPC:A61K9/22, C07D213/82, C07D213/80, C07D211/90, // C07J43/00
[1995/34]
CPC:
C07D213/80 (EP); A61K47/559 (EP); C07D209/32 (EP);
C07D211/90 (EP); C07D213/82 (EP); C07D401/12 (EP);
C07J43/003 (EP); C07K14/70 (EP); A61K38/00 (EP) (-)
Former IPC [1984/25]A61K9/22, C07D213/82, C07D213/80, C07D211/90, // C07C103/52, C07J43/00
Designated contracting statesAT,   BE,   CH,   DE,   FR,   GB,   LI,   LU,   NL,   SE [1984/25]
TitleGerman:GEHIRNSPEZIFISCHE ARZNEIMITTELABGABE[1984/25]
English:BRAIN-SPECIFIC DRUG DELIVERY[1984/25]
French:ADMINISTRATION D'UN MEDICAMENT A ACTION SPECIFIQUE SUR LE CERVEAU[1984/25]
MiscellaneousEPB 1995/34: Divisional applications 86201714, 86201711, 86201713 filed on 03.10.86, divisional application 87201384 filed on 21.07.87
Entry into regional phase03.01.1984National basic fee paid 
03.01.1984Designation fee(s) paid 
03.01.1984Examination fee paid 
Examination procedure13.01.1984Examination requested  [1984/25]
31.05.1985Despatch of a communication from the examining division (Time limit: M06)
28.10.1985Reply to a communication from the examining division
03.02.1986Despatch of a communication from the examining division (Time limit: M08)
01.10.1986Reply to a communication from the examining division
11.05.1988Despatch of a communication from the examining division (Time limit: M08)
07.01.1989Reply to a communication from the examining division
28.08.1990Despatch of a communication from the examining division (Time limit: M08)
19.04.1991Reply to a communication from the examining division
27.08.1991Despatch of a communication from the examining division (Time limit: M06)
24.02.1992Reply to a communication from the examining division
06.12.1993Despatch of a communication from the examining division (Time limit: M06)
07.04.1994Reply to a communication from the examining division
18.05.1994Despatch of communication of intention to grant (Approval: Yes)
22.11.1994Communication of intention to grant the patent
14.02.1995Fee for grant paid
14.02.1995Fee for publishing/printing paid
Divisional application(s)EP86201710.0  / EP0218300
EP86201711.8  / EP0221588
EP86201713.4  / EP0224283
EP86201714.2  / EP0222425
EP87201384.2  / EP0262696
EP87201385.9  / EP0256577
Opposition(s)24.05.1996No opposition filed within time limit [1996/33]
Fees paidRenewal fee
13.04.1985Renewal fee patent year 03
12.03.1986Renewal fee patent year 04
19.03.1987Renewal fee patent year 05
16.04.1988Renewal fee patent year 06
19.04.1989Renewal fee patent year 07
23.05.1990Renewal fee patent year 08
17.05.1991Renewal fee patent year 09
11.05.1992Renewal fee patent year 10
26.05.1993Renewal fee patent year 11
09.05.1994Renewal fee patent year 12
12.04.1995Renewal fee patent year 13
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Licence(s)ID:01 00/exclusive
For:AT BE CH DE FR GB LI LU NL SE
Licencee:Pharmatec, Inc. P.O. Box 730
Alachua
Florida 32615 / US
Date:28.07.1989
Former [1989/37]ID:01 00/exclusive
For:all designated states
Licencee:Pharmatec, Inc. P.O. Box 730
Alachua
Florida 32615 / US
Date:
Lapses during opposition  TooltipNL23.08.1995
SE23.11.1995
[2003/07]
Former [1996/14]SE23.11.1995
Cited inInternational search[A]US3962447  (HIGUCHI TAKERU, et al)
 [X]  - Science, Vol. 214, No. 4527, published in 1981 (Washington D.C., US) N. BODOR et al.: "Site Specific, Sustained Release of Drugs to the Brain", pages 1370-1372, see the complete article
 [X]  - Journal of Pharmaceutical Sciences, Vol. 67, No. 5, published in May 1978 (Washington D.C., US) N. BODOR et al.: "Elimination of a Quaternary Pyridinium Salt, Delivered as its Dihydropyridine Derivative from Brain of Mice", pages 685-687, see the complete article
 [A]  - Chemical and Engineering News, published 21 December 1981 (Washington D.C., US) R. RAWLS: "New Methods let Drugs past Blood-Brain Barrier", pages 24, 25
 [XP]  - Journal of Medicinal Chemistry, Vol. 26, published in April 1983 (Columbus, Ohio, US) N. BODOR: "Improved Delivery Through Biological Membranes. 13. Brain Specific Delivery of Dopamine with a Dihydropyridine - Pyridinium Salt Redox Type Delivery System", pages 528-534, see the complete article
 [XP]  - Journal of Medicinal Chemistry, Vol. 26, published in March 1983 (Columbus, Ohio, US) N. BODOR et al.: "Improved Delivery Through Biological Membranes. 11. A Redox Chemical Drug-Delivery System and its use for Brain-Specific Delivery of Phenekylamine", pages 313-317, see the complete article
Examination   - DRUGS OF THE FUTURE, VOL. VI, NO. 3, 1981, PAGES 165-182
    - OPTIMIZATION OF DRUG DELIVERY, ED. H. BUNDGAARD, A.B.HANSEN AND H. KOFOD, PUB. MUNKSGAARD, COPENHAGEN, 1982, PAGES 157-177
    - DRUG DELIVERY SYSTEMS, ED. R.L.JULIANO, OXFORD UNIVERSITY PRESS, 1980, PAGES 112-176
    - CHEMISTRY AND INDUSTRY, 7TH JUNE, 1980, PAGES 441-443
    - DESIGN OF BIOPHARMACEUTICAL PROPERTIES THROUGH PRODRUGS AND ANALOGS, ED. E.B.ROCHE, AMERICAN PHARMACEUTICAL ASSOCIATION, 1977, PAGES 98-135
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.