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Extract from the Register of European Patents

EP About this file: EP0218300

EP0218300 - Brain-specific drug delivery [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 18.04.1995 Database last updated on 02.09.2024
Most recent event Tooltip	07.07.2007	Change - inventor	published on 08.08.2007 [2007/32]
Applicant(s)	For all designated states University of Florida P.O. Box 115500 Gainesville Florida 32611-5500 / US
	[N/P]
Former [1987/16]	For all designated states UNIVERSITY OF FLORIDA 207 Tigert Hall Gainesville, Florida 32611 / US
Inventor(s)	01 / Bodor, Nicholas S. 7211 South West 97th Lane Gainesville Florida 32608 / US
	[1987/16]
Representative(s)	Pendlebury, Anthony, et al PAGE, WHITE & FARRER 54 Doughty Street London WC1N 2LS / GB
	[1987/16]
Application number, filing date	86201710.0	12.05.1983
	[1987/16]
Priority number, date	US19820379316	18.05.1982 Original published format: US 379316
	US19830461543	27.01.1983 Original published format: US 461543
	US19830475493	15.03.1983 Original published format: US 475493
	[1987/16]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	EP0218300
	Date:	15.04.1987
	Language:	EN
	[1987/16]
	Type:	A3 Search report
	No.:	EP0218300
	Date:	28.09.1988
	Language:	EN
	[1988/39]
Search report(s)	(Supplementary) European search report - dispatched on:	EP	10.08.1988
Classification	IPC:	C07D215/54, C07D401/12, C07D417/12, C07D401/14, C07J43/00, A61K47/00	[1987/16]
	CPC:	C07D213/80 (EP); A61K47/559 (EP); C07D209/32 (EP); C07D211/90 (EP); C07D213/82 (EP); C07D401/12 (EP); (+) C07J43/003 (EP); C07K14/70 (EP); A61K38/00 (EP) (-)
Designated contracting states	AT, BE, CH, DE, FR, GB, LI, LU, NL, SE [1987/16]
Title	German:	Gehirnspezifische Arzneimittelabgabe	[1987/16]
	English:	Brain-specific drug delivery	[1987/16]
	French:	Administration d'un médicament à action spécifique sur le cerveau	[1987/16]
Examination procedure	20.03.1989	Examination requested [1989/21]
	27.07.1992	Despatch of a communication from the examining division (Time limit: M10)
	12.05.1993	Reply to a communication from the examining division
	08.07.1993	Despatch of a communication from the examining division (Time limit: M10)
	07.04.1994	Reply to a communication from the examining division
	01.12.1994	Application deemed to be withdrawn, date of legal effect [1995/23]
	10.01.1995	Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [1995/23]
Parent application(s) Tooltip	EP83902034.4 / EP0110955
Fees paid	Renewal fee
	03.10.1986	Renewal fee patent year 03
	03.10.1986	Renewal fee patent year 04
	19.03.1987	Renewal fee patent year 05
	21.03.1988	Renewal fee patent year 06
	19.04.1989	Renewal fee patent year 07
	15.05.1990	Renewal fee patent year 08
	17.05.1991	Renewal fee patent year 09
	11.05.1992	Renewal fee patent year 10
	26.05.1993	Renewal fee patent year 11
	Penalty fee
	Additional fee for renewal fee
	31.05.1994	12 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Licence(s)	ID:	01 00/exclusive
	For:	AT BE CH DE FR GB LI LU NL SE
	Licencee:	Pharmatec, Inc. P.O. Box 730 Alachua Florida 32615 / US
	Date:	28.07.1989
Former [1989/37]	ID:	01 00/exclusive
	For:	all designated states
	Licencee:	Pharmatec, Inc. P.O. Box 730 Alachua Florida 32615 / US
	Date:
Documents cited:	Search	[X] - SCIENCE, vol. 214, no. 4527, 18th December 1981; N. BODOR et al.: "Site-Specific, Sustained Release of Drugs to the Brain"
		[X] - JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 67, no. 5, May 1978, pages 685-687, Washington, D.C., US; N. BODOR et al.: "Elimination of a quaternary pyridinium salt, delivered as its dihydropyridine derivative from brain of mice"
		[X] - CHEMICAL AND ENGINEERING NEWS, 21st December 1981, pages 24,25, Washington, D.C., US; R. RAWLS: "New methods let drugs past blood-brain barrier"
		[X] - "Drug delivery systems", Ed. R.L. JULIANO, 1980, pages 112-176, Oxford University Press; V. STELLA et al.
		[X] - "Design of Biopharmaceutical Properties through Prodrugs and Analogs", Ed. B. ROCHE (editor), Am. Pharm. Assoc. 1977, pages 98-135
		[AP] - JOURNAL OF MEDICINAL CHEMISTRY, vol. 26, April 1983, pages 313-317, Columbus, Ohio, US; N. BODOR et al.: "Improved delivery through biological membranes. 11. A redox chemical drug-delivery system and its use for brain-specific delivery of phenekylamine"
		[AP] - JOURNAL OF MEDICINAL CHEMISTRY, vol. 26, April 1983, pages 528-534, Columbus, Ohio, US; N. BODOR et al.: "Improved delivery through biological membranes. 13. Brain specific delivery of dopamine with a dihydropyridine pyridinium salt type redox delivery system"

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