blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP0270290

EP0270290 - Method and compositions for reducing neurotoxic injury [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  19.04.2002
Database last updated on 11.09.2024
Most recent event   Tooltip05.10.2005Change: Appeal number 
Applicant(s)For all designated states
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
350 Cambridge Avenue, Suite 250 Palo Alto
California 94306 / US
[N/P]
Former [1988/23]For all designated states
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
350 Cambridge Avenue, Suite 250
Palo Alto, California 94306 / US
Inventor(s)01 / Choi, Dennis W.
739 San Rafael Place
Stanford California 94305 / US
[1988/23]
Representative(s)Harrison, David Christopher, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[N/P]
Former [1994/28]Harrison, David Christopher, et al
MEWBURN ELLIS York House 23 Kingsway
London WC2B 6HP / GB
Former [1988/23]Harrison, David Christopher
MEWBURN ELLIS York House 23 Kingsway
London WC2B 6HP / GB
Application number, filing date87310323.823.11.1987
[1988/23]
Priority number, dateUS1986093473325.11.1986         Original published format: US 934733
[1988/23]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0270290
Date:08.06.1988
Language:EN
[1988/23]
Type: A3 Search report 
No.:EP0270290
Date:03.06.1992
Language:EN
[1992/23]
Search report(s)(Supplementary) European search report - dispatched on:EP16.04.1992
ClassificationIPC:A61K31/415
[1992/23]
CPC:
A61K31/485 (EP,KR,US); A61P25/00 (EP); A61P25/08 (EP);
A61P25/28 (EP); A61P3/08 (EP); A61P9/00 (EP);
A61P9/10 (EP) (-)
Former IPC [1988/23]A61K31/485
Designated contracting statesAT,   BE,   CH,   DE,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1988/23]
TitleGerman:Methode und Präparate zur Reduzierung neurotoxischer Schäden[1988/23]
English:Method and compositions for reducing neurotoxic injury[1988/23]
French:Méthode et compositions pour la réduction de blessure neurotoxique[1988/23]
Examination procedure25.11.1992Examination requested  [1993/03]
11.05.1993Despatch of a communication from the examining division (Time limit: M06)
28.12.1993Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
24.02.1994Reply to a communication from the examining division
03.08.1994Despatch of a communication from the examining division (Time limit: M06)
27.12.1994Reply to a communication from the examining division
20.09.1995Date of oral proceedings
02.04.1996Despatch of communication that the application is refused, reason: substantive examination {1}
02.04.1996Minutes of oral proceedings despatched
30.07.1998Application withdrawn by applicant  [2002/23]
Appeal following examination10.06.1996Appeal received No.  T0837/96
09.08.1996Statement of grounds filed
22.05.1998Invitation to file observations in an appeal (Time limit: M02) [1998/21]
29.07.1998Result of appeal procedure: appeal of the applicant withdrawn
Request for further processing for:24.02.1994Request for further processing filed
28.02.1994Full payment received (date of receipt of payment)
Request granted
23.03.1994Decision despatched
Fees paidRenewal fee
09.11.1989Renewal fee patent year 03
20.11.1990Renewal fee patent year 04
11.11.1991Renewal fee patent year 05
14.10.1992Renewal fee patent year 06
08.11.1993Renewal fee patent year 07
15.11.1994Renewal fee patent year 08
27.11.1995Renewal fee patent year 09
29.11.1996Renewal fee patent year 10
27.11.1997Renewal fee patent year 11
Penalty fee
Additional fee for renewal fee
30.11.199812   M06   Not yet paid
30.11.200115   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XP]WO8701036  (UNIV NEW YORK [US]);
 [YP]EP0230370  (MERCK SHARP & DOHME [GB])
 [X]  - BRAIN RES., vol. 383, nos. 1-2, 24th September 1986, pages 314-318; F.C. TORTELLA et al.: "Dextromethorphan and carbetapentane: centrally acting non-opioid antitussive agents with novel anticonvulsant properties"
 [Y]  - BIOCHEM. PHARMACOL., vol. 33, no. 23, 1st December 1984, pages 3829-3832, Pergamon Press Ltd, GB; S.C. BERRY et al.: "Benz(f)isoquinolines as excitatory amino acid antagonists: an indication of their mechanism of action?"
 [Y]  - THE LANCET, 20th July 1985, pages 140-143; R. SCHWARCZ: "Exitatory aminoacid antagonists provide a therapeutic approach to neurological disorders"
 [Y]  - CLINICAL SCIENCE, vol. 68, 1985, pages 113-122; B. MELDRUM: "Possible therapeutic applications of antagonists of excitatory anino acid neurotransmitters"
 [YD]  - EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 111, no. 2, 8th May 1985, pages 185-190, Elsevier Science Publishers B.V.; H. CHURCH et al.: "Differential effects of dextrorphan and levorphanol on the excitation of rat spinal neurons by amino acids"
 [Y]  - SOCIETY FOR NEUROSCIENCE ABSTRACTS, vol. 12, no. 1, 1986, page 64; M.P. GOLDBERG et al.: "Hypoxic cortical neuronal injury is blocked by N-methyl-D-aspartate receptor antagonists"
 [YD]  - SOCIETY FOR NEUROSCIENCE ABSTRACTS, vol. 12, no. 1, 1986, pages 381; D.W. CHOI et al.: "Glutamate neurotoxicity in cortical cell culture is attenuated by N-methyl-D-aspartate receptor antagonists"
 [X]  - SCIENCE; vol. 215, no. 4528, 1st January 1982, pages 69-71; AAAS; Y. HOSOBUCHI et al.: "Reversal of induced ischemic neurologic deficit in gerbils by the opiate antagonist naloxone"
 [XP]  - NEUROSCIENCE LETTERS, vol. 80, 11th September 1987, pages 11-15, Elsevier Scientific Publishers Ireland Ltd; M.P. GOLDBERG et al.: "Dextrorphan and dextromethorphan attenuate hypoxic injury in neuronal culture"
 [T]  - CLINICAL NEUROPHARMACOLOGY, vol. 12, no. 4, August 1989, pages 322-330, Raven Press, Ltd, New York, US; F.O. WALKER et al.: "An open label trial of dextromethorphan in Huntington's Disease"
 [T]  - ARZNEIM.-FORSCH./DRUG RES., vol. 41(I), no. 3a, 1991, pages 303-309; J. KRIEGLSTEIN et al.: "Pharmakologische Grundlagen der Therapie der zerebralen Ischämie"
 [T]  - CHEMICAL ABSTRACTS, vol. 109, no. 7, 15th August 1988, page 64, abstract no. 48319g, Columbus, Ohio, US; G.K. STEINBERG et al.: "Delayed treatment with dextromethorphan and dextrorphan reduces cerebral damage after transient focal ischemia" & NEUROSCI. LETT. 1988, 89(2), 193-7
 [T]  - CHEMICAL ABSTRACTS, vol. 107, no. 17, 26th October 1987, page 62, abstract no. 147309u, Columbus, Ohio, US; M.P. GOLDBERG et al.: "Dextrorphan and dextromethorphan attenuate hypoxic injury in neuronal culture" & NEUROSCI. LETT. 1987, 80(1), 11-15
 [T]  - CHEMICAL ABSTRACTS, vol. 111, no. 21, 20th November 1989, pages 68-69, abstract no. 187420n, Columbus, Ohio, US; G.K. STEINBERG et al.: "Protective effect of N-methyl-D-aspartate antagonists after focal cerebral ischemia in rabbits"
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.