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Extract from the Register of European Patents

EP About this file: EP0291633

EP0291633 - Use of 3'-azido-3'-deoxythymidine in the treatment or prophylaxis of human retroviral infections [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  04.09.1993
Database last updated on 05.10.2024
Most recent event   Tooltip04.09.1993No opposition filed within time limitpublished on 27.10.1993 [1993/43]
Applicant(s)For all designated states
THE WELLCOME FOUNDATION LIMITED
Unicorn House 160 Euston Road P.O. Box 129
London NW1 2BP / GB
[N/P]
Former [1988/47]For all designated states
THE WELLCOME FOUNDATION LIMITED
Unicorn House 160 Euston Road
London NW1 2BP / GB
Inventor(s)01 / Rideout, Janes Litster
3101 Morningside Drive
Raleigh, NC / US
02 / Barry, David Walter
1810S Lakeshore Drive
Chapel Hill, NC / US
03 / Lehrman, Sandra Nusinoff
2720 Old Sugar Road
Durham, NC / US
04 / St Clair, Martha Heider
312 Seven Oaks Road
Durham, NC / US
05 / Furman, Phillip Allen
901 Bluestone Road
Durham, NC / US
[1992/45]
Former [1988/47]01 / Rideout, Janes Litster
3101 Morningside Drive
Raleigh North Carolina / US
02 / Barry, David Walter
1810S Lakeshore Drive
Chapel Hill North Carolina / US
03 / Lehrman, Sandra Nusinoff
2720 Old Sugar Road
Durham North Carolina / US
04 / St Clair, Martha Heider
312 Seven Oaks Road
Durham North Carolina / US
05 / Furman, Phillip Allen
901 Bluestone Road
Durham North Carolina / US
Representative(s)Garrett, Michael, et al
Glaxo Wellcome plc, Glaxo Wellcome House, Berkeley Avenue Greenford
Middlesex UB6 0NN / GB
[N/P]
Former [1988/47]Garrett, Michael, et al
The Wellcome Research Laboratories Group Patents and Agreements Langley Court
Beckenham Kent BR3 3BS / GB
Application number, filing date88101790.914.03.1986
[1988/47]
Priority number, dateGB1985000686916.03.1985         Original published format: GB 8506869
GB1985001177409.05.1985         Original published format: GB 8511774
GB1985002388127.09.1985         Original published format: GB 8523881
GB1986000345012.02.1986         Original published format: GB 8603450
US1985077689917.09.1985         Original published format: US 776899
[1988/47]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP0291633
Date:23.11.1988
Language:EN
[1988/47]
Type: B1 Patent specification 
No.:EP0291633
Date:04.11.1992
Language:EN
[1992/45]
Search report(s)(Supplementary) European search report - dispatched on:EP20.06.1988
ClassificationIPC:A61K31/70, C07H19/073
[1988/47]
CPC:
A61K31/70 (EP); A61K31/7072 (EP); A61K38/212 (EP);
A61P31/12 (EP); A61P31/18 (EP); C07H19/06 (EP);
C07H19/10 (EP) (-)
C-Set:
A61K38/212, A61K2300/00 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   FR,   GB,   IT,   LI,   LU,   NL,   SE [1988/47]
TitleGerman:Verwendung von 3'-Azido-3'-deoxythymidin zur Behandlung oder Vorbeugung von menschlichen Retrovirus-Infektionen[1988/47]
English:Use of 3'-azido-3'-deoxythymidine in the treatment or prophylaxis of human retroviral infections[1988/47]
French:Utilisation de la 3'azido-3'-déoxythymidine pour le traitement ou la prophylaxie des infections humaines à rétrovirus[1988/47]
Examination procedure08.02.1988Examination requested  [1988/47]
18.05.1990Despatch of a communication from the examining division (Time limit: M04)
13.09.1990Reply to a communication from the examining division
04.04.1991Despatch of a communication from the examining division (Time limit: M02)
28.05.1991Reply to a communication from the examining division
16.10.1991Despatch of communication of intention to grant (Approval: No)
12.04.1992Despatch of communication of intention to grant (Approval: later approval)
24.04.1992Communication of intention to grant the patent
21.07.1992Fee for grant paid
21.07.1992Fee for publishing/printing paid
Parent application(s)   TooltipEP86301897.4  / EP0196185
Opposition(s)05.08.1993No opposition filed within time limit [1993/43]
Fees paidRenewal fee
08.02.1988Renewal fee patent year 03
19.12.1988Renewal fee patent year 04
22.12.1989Renewal fee patent year 05
01.12.1990Renewal fee patent year 06
04.12.1991Renewal fee patent year 07
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Documents cited:Search[X]  - EXPERIMENTAL CELL RESEARCH, vol. 116, no. 1, 1978, pages 31-37, Academic Press Inc., SE; W. OSTERTAG et al.: "Induction of intracisternal A-type particles during friend cell differentiation"
 [XD]  - EXPERIMENTAL CELL RESEARCH, vol. 116, no. 1, 1978, pages 21-29, Academic Press Inc., SE; C.J. KRIEG et al.: "Increase in intracisternal A-type particles in friend cells during inhibition of friend virus (SFFV) release by interferon or azidothymidine"
 [XD]  - PROC. NAT. ACAD. SCI. USA, vol. 71, no. 12, December 1974, pages 4980-4985, US; W. OSTERTAG et al.: "Induction of endogenous virus and of thymidine kinase by bromodeoxyuridine in cell cultures transformed by friend virus"
 [XP]  - PROC. NATL. ACAD. SCI. USA, vol. 82, October 1985, pages 7096-7100, US; H. MITSUYA et al.: "3'-azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro"
 [XP]  - DIALOG INFORMATION SERVICES, file 267; DeHaen Drug Data, 1980-1987; & 25TH INTERSCIENCE CONFERENCE ANTIMICROBIAL AGENTS CHEMOTHERAPY, Minneapolis, US, September 29 - October 2, 1985; Abstracts no. 437-440. Réf. no. 0180178: M.H. St CLAIR et al.: "Characterization of HTLV-3 reverse transciotase and inhibition by the triphosphate of BW A509U." & Abstract 439
 [XP]  - DIALOG INFORMATION SERVICES, file 267; DeHaen Drug Data, 1980-1987; & 25TH INTERSCIENCE CONFERENCE ANTIMICROBIAL AGENTS CHEMOTHERAPY, Minneapolis, US, September 29 - October 2, 1985; Abstracts no. 437-440. Réf. no. 0180181: W.D. HARDY Jr. et al.: "Anti-viral effects of BW A509U against a naturally occuring feline acquired immune deficiency syndrome (FAIDS)-inducing retrovirus" & Abstract 438
 [XP]  - DIALOG INFORMATION SERVICES, file 267; DeHaen Drug Data, 1980-1987; & 25TH INTERSCIENCE CONFERENCE ANTIMICROBIAL AGENTS CHEMOTHERAPY, Minneapolis, US, September 29 - October 2, 1985; Abstracts no. 440. Réf. no. 0180180: H. MITSUYA et al.: "BW A509U blocks HTLV-3 infection of T lymphocytes in culture" & Abstract 437
 [XP]  - DIALOG INFORMATION SERVICES, file 267; DeHaen Drug Data, 1980-1987; & 25TH INTERSCIENCE CONFERENCE ANTIMICROBIAL AGENTS CHEMOTHERAPY, Minneapolis, US, September 29 - October 2, 1985; Abstracts no. 440. Réf. no. 0180179: P.A. FURMAN et al.: "Selective inhibition of HTLV-3 by BW A509U." & Abstract 440
 [XP]  - JOURNAL OF THE AM. MED. ASSOC., vol. 254, no. 18, 8 November 1985, pages 2521,2527,2529: D.E. RIESENBERG: "Anti-AIDS agents show varying early results in vitro and in vivo"
 [XP]  - DIALOG INFORMATION SERVICES, file 5; Biosis Previews 69-87; June, Réf. no. 0016194545: W.D. HARDY Jr. et al.: "Azidothymidine inhibits the replication of the feline leukemia virus." & J. CELL BIOCHEM. suppl. 0 (10 part A9, 1986, 207
 [XP]  - CHEM. & ENG. NEWS, vol. 64, no. 4, 27th january 1986, pages 28-40; R.K. ROBINS: "Synthetic antiviral agents"
 [XP]  - FDA DRUG BULLETIN, vol. 15, no. 3, October 1985, pages 27-32, NN: "Progress on AIDS"
 [XP]  - PROCEEDINGS OF AM. ASSOC. CANCER RES., vol. 27, 77th Meeting, March 1986, page 422, ref. no. 1675; R.M. RUPRECHT et al.: "3'-Azido-3'-deoxythymidine (AZT) as antiretroviral agent in murine systems in vitro and in vivo"
 [XP]  - PROCEEDINGS OF AM. SOC. CLIN. ONCOL., vol. 5, 22nd Meeting, March 1986, page 1, ref. no. 4; R.W. KLECKER et al.: "Clinical pharmacology of 3'-azido-3'-deoxythymidine (N3TdR), a novel pyrimidine analog with potential application for the treatment of patients with AIDS and related diseases"
 [A]  - CANCER RESEARCH, vol. 32, no. 7, July 1972, pages 1547-1553; A.W. SCHRECKER et al.: "Inhibition of RNA-dependent DNA polymerase by thymidylate derivatives"
 [T]  - NATURE, vol. 323, 2nd October 1986, pages 467-469; R.M. RUPRECHT et al.: "Suppression of mouse viraemia and retroviral disease by 3'-azido-3'-deoxythymidine"
 [T]  - THE LANCET, vol. 1, no 8539, 25th April 1987, pages 957-958; NN: "Zidovudine (AZT)"
Examination   - PROCEEDINGS OF THE NATL. ACADEMY OF SCIENCE USA, vol. 71, no. 12, December 1974; W.OSTERTAG et al., pp. 4980-4985*
    - PROCEEDINGS OF THE NATL. ACADEMY OF SCIENCE USA, vol. 82, October 1985; H.MITSUYA et al., pp. 7096-7100*
    - DIALOG INFORMATION SERVICES, file 267; DeHaen Drug Data, 1980-1987, & 25TH INTERSCIENCE CONFERENCE ANTIMICROBIAL AGENTS CHEMOTHERAPY, Minneapolis, MN, (US); 29 September-02 October 1985; @M.H.St CLAIR et al., nos. 437-440, ref.0180178* @W.D.HARDY Jr. et al., nos. 437-440, ref. 0180181* @H.MITSUYA et al., no. 440, ref. 0180180* @P.A.FURMAN et al., no. 440, ref. 0180179*
    - JOURNAL OF THE AM. MED. ASSOC., vol. 254, no. 18, 08 November 1985; D.E.RIESENBERG, pp. 2521, 2527, 2529*
    - NATURE, vol. 323, 02 October 1986; R.M.RUPRECHT et al., pp. 467-469*
    - THE LANCET, 26 August 1989; pp. 483-484*
    - THE LANCET, 20 February 1988; pp. 373-376*
    - THE LANCET, 07 April 1990; pp. 821-822*
    - AM. J. MED., vol. 85, 1988; pp. 176-181*
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.