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Extract from the Register of European Patents

EP About this file: EP0291533

EP0291533 - RNA RIBOZYME RESTRICTION ENDORIBONUCLEASES AND METHODS [Right-click to bookmark this link]
Former [1988/47]RNA RIBOZYME POLYMERASES, DEPHOSPHORYLASES, RESTRICTION ENDORIBONUCLEASES AND METHODS
[1995/42]
StatusPatent revoked
Status updated on  17.06.2005
Database last updated on 02.11.2024
Most recent event   Tooltip25.07.2008Change - opposition data/opponents data or that of the opponents representativepublished on 27.08.2008  [2008/35]
Applicant(s)For all designated states
UNIVERSITY PATENTS, INC.
1465 Post Road East, P.O. Box 901 Westport
Connecticut 06881 / US
[N/P]
Former [1988/47]For all designated states
UNIVERSITY PATENTS, INC.
1465 Post Road East, P.O. Box 901
Westport, Connecticut 06881 / US
Inventor(s)01 / CECH, Thomas, R.
1545 Rockmont Circle
Boulder, CO 80303 / US
02 / ZAUG, Arthur, J.
623 W. Lilac Court
Louisville, CO 80027 / US
03 / BEEN, Michael, D.
705 Aurora Avenue, Apt. 4
Boulder, CO 80300 / US
[1988/47]
Representative(s)Jaenichen, Hans-Rainer, et al
Vossius & Partner
Postfach 86 07 67
81634 München / DE
[N/P]
Former [1996/42]Jaenichen, Hans-Rainer, Dr., et al
Vossius & Partner, Postfach 86 07 67
81634 München / DE
Former [1992/34]Goldin, Douglas Michael, et al
J.A. KEMP & CO. 14, South Square Gray's Inn
London WC1R 5LX / GB
Former [1992/33](deleted)
Former [1990/15]Schulze Horn, Stefan, Dipl.-Ing. M.Sc.
Goldstrasse 50
D-48147 Münster / DE
Former [1988/47]Patentanwälte Schulze Horn und Hoffmeister
Goldstrasse 36
D-48147 Münster / DE
Application number, filing date88901380.102.12.1987
[1988/47]
WO1987US03161
Priority number, dateUS1986093732703.12.1986         Original published format: US 937327
[1988/47]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO8804300
Date:16.06.1988
Language:EN
[1988/13]
Type: A1 Application with search report 
No.:EP0291533
Date:23.11.1988
Language:EN
The application published by WIPO in one of the EPO official languages on 16.06.1988 takes the place of the publication of the European patent application.
[1988/47]
Type: B1 Patent specification 
No.:EP0291533
Date:18.10.1995
Language:EN
[1995/42]
Search report(s)International search report - published on:US16.06.1988
(Supplementary) European search report - dispatched on:EP12.10.1989
ClassificationIPC:C07H17/02, C12N9/12, C12N9/22, C12N15/10
[1995/42]
CPC:
C12N15/113 (EP,US); C12N15/10 (EP,US); C12N2310/111 (EP,US);
C12N2310/1241 (EP,US)
Former IPC [1988/47]C07H17/02, C12N9/12, C12N9/22, C12N15/00
Designated contracting statesAT,   BE,   CH,   DE,   FR,   GB,   IT,   LI,   LU,   NL,   SE [1988/47]
TitleGerman:RNS-RIBOZYM RESTRIKTIONSENDORIBONUKLEASEN UND VERFAHREN[1995/42]
English:RNA RIBOZYME RESTRICTION ENDORIBONUCLEASES AND METHODS[1995/42]
French:RIBOZYME D'ARN ENDORIBONUCLEASES DE RESTRICTION ET PROCEDES[1995/42]
Former [1988/47]RNS-RIBOZYM-POLYMERASEN, DEPHOSPHORYLASEN, RESTRIKTION VON ENDORIBONUKLEASEN UND VERFAHREN
Former [1988/47]RNA RIBOZYME POLYMERASES, DEPHOSPHORYLASES, RESTRICTION ENDORIBONUCLEASES AND METHODS
Former [1988/47]POLYMERASES DE RIBOZYME D'ARN, DEPHOSPHORYLASES ENDORIBONUCLEASES DE RESTRICTION ET PROCEDES
Entry into regional phase26.07.1988National basic fee paid 
26.07.1988Search fee paid 
26.07.1988Designation fee(s) paid 
19.11.1988Examination fee paid 
Examination proceduredeletedDecision about request for accelerated examination - accepted: No
19.11.1988Examination requested  [1989/03]
06.10.1992Despatch of a communication from the examining division (Time limit: M04)
01.12.1992Reply to a communication from the examining division
18.12.1992Despatch of a communication from the examining division (Time limit: M04)
14.04.1993Reply to a communication from the examining division
21.10.1993Despatch of a communication from the examining division (Time limit: M04)
24.01.1994Reply to a communication from the examining division
22.02.1994Despatch of a communication from the examining division (Time limit: M04)
03.06.1994Reply to a communication from the examining division
02.09.1994Despatch of a communication from the examining division (Time limit: M04)
26.10.1994Reply to a communication from the examining division
21.12.1994Despatch of a communication from the examining division (Time limit: M04)
01.02.1995Reply to a communication from the examining division
01.02.1995Request for accelerated examination filed
08.03.1995Date of oral proceedings
07.04.1995Minutes of oral proceedings despatched
18.04.1995Despatch of communication of intention to grant (Approval: Yes)
28.04.1995Communication of intention to grant the patent
03.05.1995Fee for grant paid
03.05.1995Fee for publishing/printing paid
Opposition(s)Opponent(s)01  17.07.1996  31.07.1996  ADMISSIBLE
GENE SHEARS PTY LIMITED
Administration Building-CNR Barry Drive Clunies Ross Street GPO Box 1600
CANBERRA ACT 2601 / AU
Opponent's representative
Almond-Martin, Carol
Ernest Gutmann - Yves Plasseraud S.A.S. 88, Boulevard des Belges
69452 Lyon Cedex 06 / FR
 02  18.07.1996  26.10.2000  WITHDRAWN
Innovir Laboratories, Inc.
510 East 73rd Street
New York / US
Opponent's representative
Bassett, Richard Simon
Potter Clarkson LLP The Belgrave Centre
Talbot Street
Nottingham NG1 5GG / GB
 03  18.07.1996  11.09.1996  ADMISSIBLE
Immusol Incorporated
3050 Science Park Road
San Diego, CA 92121 / US
Opponent's representative
Walton, Seán Malcolm
Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
 [N/P]
Former [2008/35]
Opponent(s)01  17.07.1996  31.07.1996  ADMISSIBLE
GENE SHEARS PTY LIMITED
Administration Building-CNR Barry Drive Clunies Ross Street GPO Box 1600
CANBERRA ACT 2601 / AU
Opponent's representative
Almond-Martin, Carol
ERNEST GUTMANN - YVES PLASSERAUD S.A.S. 88, Boulevard des Belges
69452 Lyon Cedex 06 / FR
 02  18.07.1996  26.10.2000  WITHDRAWN
Innovir Laboratories, Inc.
510 East 73rd Street
New York / US
Opponent's representative
Bassett, Richard Simon
Eric Potter Clarkson, Park View House, 58 The Ropewalk
Nottingham NG1 5DD / GB
 03  18.07.1996  11.09.1996  ADMISSIBLE
Immusol Incorporated
3050 Science Park Road
San Diego, CA 92121 / US
Opponent's representative
Walton, Seán Malcolm
MEWBURN ELLIS, York House, 23 Kingsway
London WC2B 6HP / GB
Former [2005/09]
Opponent(s)01  17.07.1996  31.07.1996  ADMISSIBLE
GENE SHEARS PTY LIMITED
Administration Building-CNR Barry Drive Clunies Ross Street-GPO Box 1600
CANBERRA ACT 2601 / AU
Opponent's representative
Almond-Martin, Carol
Ernest Gutmann - Yves Plasseraud SA 88, Boulevard des Belges
69452 Lyon Cedex 06 / FR
 02  18.07.1996  26.10.2000  WITHDRAWN
Innovir Laboratories, Inc.
510 East 73rd Street
New York / US
Opponent's representative
Bassett, Richard Simon
Eric Potter Clarkson, Park View House, 58 The Ropewalk
Nottingham NG1 5DD / GB
 03  18.07.1996  11.09.1996  ADMISSIBLE
Immusol Incorporated
3050 Science Park Road
San Diego, CA 92121 / US
Opponent's representative
Walton, Seán Malcolm
MEWBURN ELLIS, York House, 23 Kingsway
London WC2B 6HP / GB
Former [1999/20]
Opponent(s)01  17.07.1996  31.07.1996  ADMISSIBLE
GENE SHEARS PTY LIMITED
Administration Building-CNR Barry Drive Clunies Ross Street-GPO Box 1600
CANBERRA ACT 2601 / AU
Opponent's representative
Almond-Martin, Carol
Ernest Gutmann - Yves Plasseraud S.A., 62 rue de Bonnel
69448 Lyon Cedex 03 / FR
 02  18.07.1996  11.09.1996  ADMISSIBLE
Innovir Laboratories, Inc.
510 East 73rd Street
New York / US
Opponent's representative
Bassett, Richard Simon
Eric Potter Clarkson, Park View House, 58 The Ropewalk
Nottingham NG1 5DD / GB
 03  18.07.1996  11.09.1996  ADMISSIBLE
Immusol Incorporated
3050 Science Park Road
San Diego, CA 92121 / US
Opponent's representative
Walton, Seán Malcolm
MEWBURN ELLIS, York House, 23 Kingsway
London WC2B 6HP / GB
Former [1996/37]
Opponent(s)01  17.07.1996  31.07.1996  ADMISSIBLE
GENE SHEARS PTY LTD
Suite 1, Building 5, 105 Delhi Road
North Ryde, NSW 2113 / AU
Opponent's representative
Almond-Martin, Carol
Ernest Gutmann - Yves Plasseraud S.A.S. 88, Boulevard des Belges
69452 Lyon Cedex 06 / FR
 02  18.07.1996    WITHDRAWN
Innovir Laboratories, Inc.
510 East 73rd Street
New York / US
Opponent's representative
Bassett, Richard Simon
Potter Clarkson LLP Park View House 58 The Ropewalk Nottingham
NG1 5DD / GB
 03  18.07.1996    ADMISSIBLE
Immusol Incorporated
3050 Science Park Road
San Diego, CA 92121 / US
Opponent's representative
Walton, Seán Malcolm
Mewburn Ellis LLP 33 Gutter Lane London
EC2V 8AS / GB
16.09.1996Invitation to proprietor to file observations on the notice of opposition
26.05.1997Reply of patent proprietor to notice(s) of opposition
16.03.1998Despatch of a communication from the opposition division (Time limit: M06)
28.09.1998Reply to a communication from the opposition division
11.07.2000Date of oral proceedings
01.08.2000Despatch of a communication from the opposition division (Time limit: M01)
01.08.2000Despatch of minutes of oral proceedings
11.09.2000Reply to a communication from the opposition division
13.06.2001Despatch of interlocutory decision in opposition
20.04.2005Legal effect of revocation of patent [2005/31]
17.06.2005Despatch of communication that the patent will be revoked
Appeal following opposition23.08.2001Appeal received No.  T0931/01
23.10.2001Statement of grounds filed
20.04.2005Result of appeal procedure: revocation of the patent
13.08.2001Appeal received No.  T0931/01
13.10.2001Statement of grounds filed
20.04.2005Date of oral proceedings
25.04.2005Minutes of the oral proceedings despatched
Fees paidRenewal fee
18.12.1989Renewal fee patent year 03
11.12.1990Renewal fee patent year 04
27.11.1991Renewal fee patent year 05
09.10.1992Renewal fee patent year 06
13.12.1993Renewal fee patent year 07
07.12.1994Renewal fee patent year 08
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Documents cited:Search[X]  - CELL, vol. 47, no. 2, pages 207-216; M.D. BEEN et al.: "One binding site determines sequence specificity of tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity"
 [X]  - BIOCHEMISTRY, vol. 25, no. 16, 12th August 1986, pages 4478-4482, American Chemical Society; A.J. ZAUG et al.: "The Tetrahymena intervening sequence ribonucleic acid enzyme is a phosphotransferase and an acid phosphatase"
 [A]  - SCIENTIFIC AMERICAN, vol. 255, no. 5, November 1986, pages 76-84, New York, US; T.R. CECH: "RNA as an enzyme"
 [A]  - SCIENCE, vol. 228, 10th May 1985, pages 719-722; J.V. PRICE et al.: "Coupling of tetrahymena ribosomal RNA splicing to beta-galactosidase expression in Escherichia coli"
International search[XP]  - Nature, Volume 324 issued 1986 December, (London, U.K.), (A. ZAUG et al), "The Tetrahymena Ribozyme Acts like an RNA restriction Endonuclease". See pages 429-433.
 [X]  - Science, Volume 321, issued 1986, January, (Washington, D.C., U.S.A.), (A. ZAUG et al), "The Intervening Sequence RNA of Tetrahymena is an Enzyme". See pages 470-475, see particularly pages 470, 471 and 475.
 [X]  - Science, Volume 224, issued 1984 May, (Washington, D.C., U.S.A.), (A. ZAUG et al), a Labile Phosphodiester Bond at the Ligation Junction in a Circular Intervening Sequence RNA", see pages 574-578, see particularly pages 574, 576, 577 and 578,
 [X]  - Biochemistry, Volume 25, issued 1986, August, (Washington, D.C., U.S.A.), (B. BASS et al) "Ribozyme Inhibitors: Deoxyguanosine and Dideoxyguanosine are Competitive Inhibitors of Self Splicing of the Tetrahymena Ribosomal Ribonucleic Acid Precursor". See pages 4473-4477, see particularly pages 4473 and 4476.
 [X]  - Proceedings National Academy of Sciences, Volume 83, issued 1986, June (Washington, D.C., U.S.A.), (T. CECH), "a Model for RNA-catalyzed Replication of RNA". See pages 4360-4363.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.