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Extract from the Register of European Patents

EP About this file: EP0362218

EP0362218 - IMPROVED METHOD FOR PRODUCING FACTOR VIII:c-TYPE PROTEINS [Right-click to bookmark this link]
StatusPatent maintained as amended
Status updated on  25.02.2000
Database last updated on 19.10.2024
Most recent event   Tooltip25.02.2000Patent maintained (B2 publication)published on 12.04.2000 [2000/15]
Applicant(s)For all designated states
GENETICS INSTITUTE, INC.
87 Cambridge Park Drive Cambridge
Massachusetts 02140 / US
[N/P]
Former [1992/40]For all designated states
GENETICS INSTITUTE, INC.
87 Cambridge Park Drive
Cambridge, Massachusetts 02140 / US
Former [1990/15]For all designated states
GENETICS INSTITUTE, INC.
87 Cambridge Park Drive
Cambridge, MA 02140 / US
Inventor(s)01 / KAUFMAN, Randal, J.
111 Marlborough Street Apartment 1
Boston, MA 02116 / US
02 / ADAMSON, S., Robert
22 Ansie Road
Chelmsford, MA 01852 / US
[1990/15]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [1990/15]VOSSIUS & PARTNER
Postfach 86 07 67
D-81634 München / DE
Application number, filing date88903710.706.04.1988
[1990/15]
WO1988US01114
Priority number, dateUS1987003488206.04.1987         Original published format: US 34882
US1987006886502.07.1987         Original published format: US 68865
[1990/15]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO8808035
Date:20.10.1988
Language:EN
[1988/23]
Type: A1 Application with search report 
No.:EP0362218
Date:11.04.1990
Language:EN
The application published by WIPO in one of the EPO official languages on 20.10.1988 takes the place of the publication of the European patent application.
[1990/15]
Type: B1 Patent specification 
No.:EP0362218
Date:05.07.1995
Language:EN
[1995/27]
Type: B2 New European patent specification 
No.:EP0362218
Date:12.04.2000
Language:EN
[2000/15]
Search report(s)International search report - published on:US20.10.1988
(Supplementary) European search report - dispatched on:EP31.07.1990
ClassificationIPC:C12P21/02, C12N15/12, C12N5/10
[1995/27]
CPC:
C07K14/755 (EP); A61K38/00 (EP)
Former IPC [1990/15]C12P21/02
Designated contracting statesAT,   BE,   CH,   DE,   FR,   GB,   IT,   LI,   LU,   NL,   SE [1990/15]
TitleGerman:VERBESSERTES VERFAHREN ZUR HERSTELLUNG VON FAKTOR VIII:c-TYP-PROTEINEN[1994/52]
English:IMPROVED METHOD FOR PRODUCING FACTOR VIII:c-TYPE PROTEINS[1990/15]
French:PROCEDE AMELIORE PERMETTANT DE PRODUIRE DES PROTEINES DE TYPE FACTEUR VIII:c[1990/15]
Former [1990/15]VERFAHREN ZUR HERSTELLUNG VON FAKTOR VIII:c-TYP-PROTEINEN
Entry into regional phase06.10.1989National basic fee paid 
06.10.1989Search fee paid 
06.10.1989Designation fee(s) paid 
06.10.1989Examination fee paid 
Examination procedure07.11.1988Request for preliminary examination filed
International Preliminary Examining Authority: DE
06.10.1989Examination requested  [1990/15]
09.06.1992Despatch of a communication from the examining division (Time limit: M06)
21.12.1992Reply to a communication from the examining division
29.04.1993Despatch of a communication from the examining division (Time limit: M04)
22.06.1993Reply to a communication from the examining division
29.10.1993Despatch of a communication from the examining division (Time limit: M04)
20.01.1994Reply to a communication from the examining division
26.04.1994Despatch of communication of intention to grant (Approval: No)
08.11.1994Despatch of communication of intention to grant (Approval: later approval)
14.11.1994Communication of intention to grant the patent
19.01.1995Fee for grant paid
19.01.1995Fee for publishing/printing paid
Opposition(s)Opponent(s)01  04.04.1996  18.04.1996  ADMISSIBLE
IMMUNO Aktiengesellschaft
Industriestrasse 67
A-1221 Wien / AT
Opponent's representative
Kolb, Helga
Hoffmann Eitle, Patent- und Rechtsanwälte, Postfach 81 04 20
81904 München / DE
 [1996/22]
10.05.1996Invitation to proprietor to file observations on the notice of opposition
09.10.1996Reply of patent proprietor to notice(s) of opposition
27.01.1998Date of oral proceedings
04.02.1998Despatch of a communication from the opposition division (Time limit: M04)
04.02.1998Despatch of minutes of oral proceedings
22.06.1998Reply to a communication from the opposition division
30.10.1998Despatch of a communication from the opposition division (Time limit: M04)
20.01.1999Reply to a communication from the opposition division
26.04.1999Despatch of interlocutory decision in opposition
06.05.1999Legal effect of interlocutory decision in opposition
13.09.1999Despatch of communication that the patent will be maintained as amended
22.12.1999Fee for printing new specification paid
Fees paidRenewal fee
26.04.1990Renewal fee patent year 03
29.04.1991Renewal fee patent year 04
29.04.1992Renewal fee patent year 05
29.04.1993Renewal fee patent year 06
29.04.1994Renewal fee patent year 07
28.04.1995Renewal fee patent year 08
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Documents cited:Search[XP]WO8704187  (GENETICS INST [US]);
 [YP]EP0251843  (TRANSGENE SA [FR]);
 [T]WO8805825  (BIOGEN NV [NL], et al)
 [YP]  - BIOTECHNOLOGY, vol. 5, April 1987, pages 389-392; A. PAVIRANI et al.: "Choosing a host cell for active recombinant factor VIII production using vaccinia virus"
International search[Y]JPS5813389  (KYOWA HAKKO KOGYO KK);
 [Y]JPS5823784  (AJINOMOTO KK);
 [Y]EP0112174  (IMMUNEX CORP [US]);
 [Y]WO8501961  (GENETICS INST [US])
 [Y]  - Nature 312, 22 November 1984, WOOD et al, "Expression of Active Human Factor VIII from Recombinant DNA Clones", pages 330-337.
 [Y]  - Journal of Clinical Investigation 60 August 1977, WEISS et al, "Stabilization of Factor VIII in Plasma by the Von Willebrand Factor", pages 390-404.
 [Y]  - Biochemical Journal 200, 1981, ANDERSON et al, "Interaction of Factor VIII - Von Willebrand Factor with Phospholipid Vesicles", pages 161-167.
 [Y]  - Cell 41, May 1985, LUNCH et al, "Molecular Cloning of cDNA for Human Von Willebrand Factor: Authentication by a New Method", pages 49-56.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.