blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP0419574

EP0419574 - MONOCLONAL ANTIBODIES TO THE LIGHT CHAIN REGION OF HUMAN FACTOR XII AND METHODS OF PREPARING AND USING THE SAME [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.09.1996
Database last updated on 02.11.2024
Most recent event   Tooltip30.11.2007Lapse of the patent in a contracting statepublished on 02.01.2008  [2008/01]
Applicant(s)For all designated states
Temple University of the Commonwealth System of Higher Education
Philadelphia
PA 19122 / US
[N/P]
Former [1991/14]For all designated states
Temple University of the Commonwealth System of Higher Education
Philadelphia PA 19122 / US
Inventor(s)01 / PIXLEY, Robin, A.
5040 Copley Road
Philadelphia, PA 19144 / US
02 / COLMAN, Robert, W.
9 Rose Valley Road
Moylan, PA 19065 / US
[1991/14]
Representative(s)WP Thompson
138 Fetter Lane
London EC4A 1BT / GB
[N/P]
Former [1991/26]W.P. THOMPSON & CO.
Eastcheap House Central Approach
Letchworth, Hertfordshire SG6 3DS / GB
Former [1991/19]Ackroyd, Robert
W.P. THOMPSON & CO. Eastcheap House Central Approach
Letchworth, Hertfordshire SG6 3DS / GB
Former [1991/14]W.P. Thompson & Co.
Coopers Building, Church Street
Liverpool L1 3AB / GB
Application number, filing date89907964.426.05.1989
[1991/14]
WO1989US02211
Priority number, dateUS1988020465709.06.1988         Original published format: US 204657
[1991/14]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO8911865
Date:14.12.1989
Language:EN
[1989/29]
Type: A1 Application with search report 
No.:EP0419574
Date:03.04.1991
Language:EN
The application published by WIPO in one of the EPO official languages on 14.12.1989 takes the place of the publication of the European patent application.
[1991/14]
Type: B1 Patent specification 
No.:EP0419574
Date:08.11.1995
Language:EN
[1995/45]
Search report(s)International search report - published on:US14.12.1989
(Supplementary) European search report - dispatched on:EP14.03.1991
ClassificationIPC:A61K39/395, C07K16/36, C12N15/00, C12N5/02
[1995/45]
CPC:
C12N9/6451 (EP,US); C07K16/40 (EP,US); C12Y304/21038 (EP,US);
A61K38/00 (EP,US)
Former IPC [1991/14]A61K39/395, C07K15/16, C12N15/00, C12N5/02
Designated contracting statesAT,   BE,   CH,   DE,   FR,   GB,   IT,   LI,   LU,   NL,   SE [1991/14]
TitleGerman:MONOKLONALE ANTIKÖRPER GEGEN DEN BEREICH DER LEICHTEN KETTE VON MENSCHLICHEM FAKTOR XII SOWIE METHODEN ZU DEREN HERSTELLUNG UND VERWENDUNG[1991/14]
English:MONOCLONAL ANTIBODIES TO THE LIGHT CHAIN REGION OF HUMAN FACTOR XII AND METHODS OF PREPARING AND USING THE SAME[1991/14]
French:ANTICORPS MONOCLONAUX CONTRE LA REGION A CHAINE LEGERE DU FACTEUR HUMAIN XII ET PROCEDES DE PREPARATION ET D'UTILISATION DE CES ANTICORPS[1991/14]
Entry into regional phase27.11.1990National basic fee paid 
27.11.1990Search fee paid 
27.11.1990Designation fee(s) paid 
27.11.1990Examination fee paid 
Examination procedure14.12.1989Request for preliminary examination filed
International Preliminary Examining Authority: DE
27.11.1990Examination requested  [1991/14]
12.08.1993Despatch of a communication from the examining division (Time limit: M04)
16.12.1993Reply to a communication from the examining division
10.08.1994Despatch of a communication from the examining division (Time limit: M04)
20.12.1994Reply to a communication from the examining division
26.01.1995Despatch of communication of intention to grant (Approval: Yes)
11.05.1995Communication of intention to grant the patent
14.07.1995Fee for grant paid
14.07.1995Fee for publishing/printing paid
Opposition(s)09.08.1996No opposition filed within time limit [1996/44]
Fees paidRenewal fee
17.05.1991Renewal fee patent year 03
11.05.1992Renewal fee patent year 04
10.05.1993Renewal fee patent year 05
02.05.1994Renewal fee patent year 06
11.05.1995Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT08.11.1995
BE08.11.1995
CH08.11.1995
IT08.11.1995
LI08.11.1995
NL08.11.1995
SE08.02.1996
LU31.05.1996
[2008/01]
Former [2003/07]AT08.11.1995
BE08.11.1995
CH08.11.1995
IT08.11.1995
LI08.11.1995
NL08.11.1995
SE08.02.1996
LU31.05.1996
Former [2000/06]AT08.11.1995
BE08.11.1995
CH08.11.1995
IT08.11.1995
LI08.11.1995
SE08.02.1996
LU31.05.1996
Former [1999/42]AT08.11.1995
BE08.11.1995
CH08.11.1995
IT08.11.1995
LI08.11.1995
SE08.02.1996
Former [1997/13]AT08.11.1995
BE08.11.1995
CH08.11.1995
LI08.11.1995
SE08.02.1996
Former [1996/31]AT08.11.1995
BE08.11.1995
SE08.02.1996
Former [1996/30]AT08.11.1995
SE08.02.1996
Former [1996/28]AT08.11.1995
Documents cited:Search[E]WO9008835  (COAGEN LTD [GB])
 [XPO]  - NATIONAL MEETING OF THE AMERICAN SOCIETY FOR CLINICAL INVESTIGATION, Washington, D.C., 28th April - 1st May 1989, page 549A; R.A. PIXLEY et al.: "Monoclonal antibodies (MAbs) to the light chain region of human factor XII (HAGEMAN FACTOR)", & CLIN. RES. 37(2), 1989
International search[X]  - Blood, Volume 65, No. 1, issued January 1985 (USA), SMALL et al, "A Monoclonal Antibody that Inhibits Activation of Human Hageman Factor (Factor XII), pages 202 to 210.
 [X]  - The journal of Clinical Investigation, Volume 78, No. 6, issued december 1986 (USA), AKIYAMA et al, "Mechanism of Activation of Coagulation Factor XI by Factor XIIa Studied with Monoclonal Antibodies, pages 1631 to 1637.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.