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Extract from the Register of European Patents

EP About this file: EP0466688

EP0466688 - GAP GENE SEQUENCES AND DIAGNOSTIC USES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.06.1998
Database last updated on 18.09.2024
Most recent event   Tooltip12.06.1998No opposition filed within time limitpublished on 29.07.1998 [1998/31]
Applicant(s)For all designated states
CHIRON CORPORATION
4560 Horton Street
Emeryville CA 94608-2916 / US
[N/P]
Former [1996/48]For all designated states
CHIRON CORPORATION
4560 Horton Street
Emeryville, California 94608 / US
Former [1992/36]For all designated states
CETUS ONCOLOGY CORPORATION
1400 Fifty-Third Street
Emeryville California 94608 / US
Former [1992/04]For all designated states
CETUS CORPORATION
1400 Fifty-Third Street
Emeryville California 94608 / US
Inventor(s)01 / WONG, Gail, L.
11255 Elvessa Street
Oakland, CA 94605 / US
02 / MCCORMICK, Francis, P.
31 Florida Avenue
Berkeley, CA 94707 / US
03 / MARTIN, George
2346 Woolsey Street
Berkeley, CA 94705 / US
04 / RUBINFELD, Bonnee
3403 Claridge Drive
Danville, CA 94526 / US
05 / O'ROURKE, Edward, C.
4414 Province Line Road
Princeton, NJ 08540 / US
06 / CLARK, Robin
7081 Colton Bld
Oakland, CA 94611 / US
07 / KOTHS, Kirston, E.
2646 Mira Vista Drive
El Cerrito, CA 94530 / US
08 / HALENBECK, Robert, F.
136 Spring Grove Avenue
San Rafael, CA 94901 / US
09 / TRAHEY, Mary, M.
137 Atlantic Avenue
San Carlos, CA 94070 / US
[1992/22]
Former [1992/04]01 / WONG, Gail, L.
11255 Elvessa Street
Oakland, CA 94605 / US
02 / MCCORMICK, Francis, P.
921 Ramona Avenue
Albany, CA 94706 / US
03 / MARTIN, George
2346 Woolsey Street
Berkeley, CA 94705 / US
04 / RUBINFELD, Bonnee
3403 Claridge Drive
Danville, CA 94526 / US
05 / O'ROURKE, Edward, C.
7321 Skyline Boulevard
Oakland, CA 94611 / US
06 / CLARK, Robin
3736 Woodruff Avenue
Oakland, CA 94602 / US
07 / KOTHS, Kirston, E.
2646 Mira Vista Drive
El Cerrito, CA 94530 / US
08 / HALENBECK, Robert, F.
136 Spring Grove Avenue
San Rafael, CA 94901 / US
09 / TRAHEY, Mary, M.
5933 Chabot Road
Oakland, CA 94618 / US
Representative(s)Bizley, Richard Edward, et al
Avidity IP
Broers Building
Hauser Forum
21 J J Thomson Ave
Cambridge CB3 0FA / GB
[N/P]
Former [1992/04]Bizley, Richard Edward, et al
Hepworth, Lawrence, Bryer & Bizley Merlin House Falconry Court Bakers Lane
Epping Essex CM16 5DQ / GB
Application number, filing date89908913.023.06.1989
[1992/04]
WO1989US02761
Priority number, dateUS1988021688808.07.1988         Original published format: US 216888
US1988023076110.08.1988         Original published format: US 230761
US1988026080721.10.1988         Original published format: US 260807
[1992/04]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO9000607
Date:25.01.1990
[1990/03]
Type: A1 Application with search report 
No.:EP0466688
Date:22.01.1992
Language:EN
The application published by WIPO in one of the EPO official languages on 25.01.1990 takes the place of the publication of the European patent application.
[1992/04]
Type: B1 Patent specification 
No.:EP0466688
Date:06.08.1997
Language:EN
[1997/32]
Search report(s)International search report - published on:EP01.11.1990
ClassificationIPC:C12N15/12, C12N15/86, C12P21/02, C07K14/00, C12Q1/68, C12Q1/42
[1997/32]
CPC:
G01N33/573 (EP); C07K14/4703 (EP); C07K14/4706 (EP);
C07K16/30 (EP); G01N33/5011 (EP); G01N33/57496 (EP);
A61K38/00 (EP); G01N2333/4707 (EP) (-)
Former IPC [1992/04]C12N15/12, C12N15/86, C12P21/02, C07K13/00, C12Q1/68, C12Q1/42
Designated contracting statesAT,   BE,   CH,   DE,   FR,   GB,   IT,   LI,   LU,   NL,   SE [1992/04]
TitleGerman:GAP-GEN-SEQUENZEN UND DIAGNOSEVERWENDUNGEN DAVON[1992/04]
English:GAP GENE SEQUENCES AND DIAGNOSTIC USES THEREOF[1992/04]
French:SEQUENCES DE GENES DE GAP ET UTILISATIONS DIAGNOSTIQUES DE TELLES SEQUENCES[1992/04]
MiscellaneousEPB 1994/42: Teilanmeldung 94111922.4 eingereicht am 23/06/89
EPB 1994/42: Divisional application 94111922.4 filed on 23/06/89
EPB 1994/42: Demande divisionnaire 94111922.4 déposée le 23/06/89
Entry into regional phase12.02.1991National basic fee paid 
12.02.1991Designation fee(s) paid 
12.02.1991Examination fee paid 
Examination procedure10.01.1990Request for preliminary examination filed
International Preliminary Examining Authority: DE
12.02.1991Examination requested  [1992/04]
17.09.1993Despatch of a communication from the examining division (Time limit: M06)
28.04.1994Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
05.07.1994Reply to a communication from the examining division
19.01.1995Despatch of a communication from the examining division (Time limit: M06)
28.07.1995Reply to a communication from the examining division
01.04.1996Despatch of communication of intention to grant (Approval: No)
04.11.1996Despatch of communication of intention to grant (Approval: later approval)
12.11.1996Communication of intention to grant the patent
02.01.1997Fee for grant paid
02.01.1997Fee for publishing/printing paid
Divisional application(s)EP94111922.4  / EP0649908
Opposition(s)07.05.1998No opposition filed within time limit [1998/31]
Request for further processing for:05.07.1994Request for further processing filed
05.07.1994Full payment received (date of receipt of payment)
Request granted
29.07.1994Decision despatched
Fees paidRenewal fee
27.05.1991Renewal fee patent year 03
18.05.1992Renewal fee patent year 04
27.05.1993Renewal fee patent year 05
27.05.1994Renewal fee patent year 06
26.05.1995Renewal fee patent year 07
28.05.1996Renewal fee patent year 08
27.05.1997Renewal fee patent year 09
Penalty fee
Penalty fee Rule 85b EPC 1973
11.02.1991M01   Fee paid on   12.02.1991
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search   [ ] - Science, Volume 238, 23 Oktober 1987, (Washington, DC, US), M. TRAHEY et al.: "A Cytoplasmic Protein Stimulates Normal N-Ras P21 GRPase, but does not affect Oncogenic Mutants", pages 542-545
    [ ] - Science, Volume 240, 22 April 1988, (Washington, DC, US), H. ADARI et al9: "Guanosine Triphosphatase Activating Protein (GAP) Interacts with the P21 Ras Effector Binding Domain", pages 518-521
    [ ] - Nature, Volume 332, 7 April 1988, (London, GB), C. CALES et al.: "The Cytoplasmic Protein GAP is Implicated as the Target for Regulation by the ras Gene Product", pages 548-551
    [ ] - Science, Volume 242, 23 December 1988, (Washington, DC, US), M. TRAHEY et al.: "Molecular Cloning of two types of GAP Complementary DNA from Human Placenta", pages 1697-1700
    [ ] - Nature, Volume 335, 1 September 1988, (London, GB), U.S. VOGEL et al.: "Cloning of Bovine GAP and its Interaction with Oncogenic Ras p21", pages 90-93
    [ ] - Biochemical and Biophysical Research Communications, Volume 159, No. 3, 31 March 1989, Academic Press, Inc., (Duluth, Mn, US), T. UEDA et al.: "GTPase Activating Proteins from the Smg-21 GTP-Binding Protein Having the Same Effector Domain as the Ras Proteins in Human Platelets", pages 1411-1419
    [ ] - Cancer Research, Volume 49, 15 March 1989, (Philadelphia, PA, US), C. DUANMU et al.: "Tubilin-Dependent Hydrolysis of Guanosine Triphosphate as a Screening Test to Identify New Antitubulin Compounds with Potential as Antimitotic Agents: Application to Carbamates of Aromatic Amines", pages 1344-1348
Examination   - Cytoplasmic Protein GAP is Implicated as the Target for Regulation by the ras Gene Product", pages 548-551
    - Cancer Research, Volume 49, 15 March 1989, (Philadelphia, PA, US), C. DUANMU et al.: "Tubilin-Dependent Hydrolysis of Guanosine Triphosphate as a Screening Test to Identify New Antitubulin Compounds with Potential as Antimitotic Agents: Application to Carbamates of Aromatic Amines", pages 1344-1348
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.