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Extract from the Register of European Patents

EP About this file: EP0425909

EP0425909 - Method for rehabilitating the vasorelaxant action of the coronary arteries impaired through atherosclerosis or hypercholesterolemia employing an ace inhibitor [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  26.04.1995
Database last updated on 12.11.2024
Most recent event   Tooltip19.06.1998Correction of patent applicationpublished on 05.08.1998 [1998/32]
Applicant(s)For all designated states
E.R. Squibb & Sons, Inc.
P.O.Box 4000 Princeton
New Jersey 08543-4000 / US
[N/P]
Former [1991/19]For all designated states
E.R. SQUIBB & SONS, INC.
P.O.Box 4000
Princeton New Jersey 08543-4000 / US
Inventor(s)01 / Aberg, Gunnar A. K.
519 Bergen Street
Lawrenceville, NJ 08648 / US
02 / Ondetti, Miguel A.
79 Hemlock Circle
Princeton, NJ 08540 / US
[1991/19]
Representative(s)Josif, Albert, et al
Baaderstrasse 3
80469 München / DE
[N/P]
Former [1991/19]Josif, Albert, Dr.-Ing., et al
Baaderstrasse 3
D-80469 München / DE
Application number, filing date90119984.418.10.1990
[1991/19]
Priority number, dateUS1989042613823.10.1989         Original published format: US 426138
[1991/19]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0425909
Date:08.05.1991
Language:EN
[1991/19]
Type: A3 Search report 
No.:EP0425909
Date:17.06.1992
Language:EN
[1992/25]
Type: A3 RE Reissue of A-publication
No.:EP0425909
Date:05.08.1998
[1998/32]
Search report(s)(Supplementary) European search report - dispatched on:EP29.04.1992
ClassificationIPC:A61K31/40, A61K31/675, A61K37/64
[1992/25]
CPC:
A61K31/675 (EP,US); A61K31/00 (EP,US); A61K31/02 (EP,US);
A61K31/40 (EP,US); A61K31/55 (EP,US); A61K31/64 (EP,US);
A61P43/00 (EP); A61P9/08 (EP); A61P9/10 (EP) (-)
Former IPC [1991/19]A61K31/40, A61K31/55, A61K31/675, A61K37/64
Designated contracting statesDE,   FR,   GB,   IT [1991/19]
TitleGerman:Verfahren zur Rehabilisierung der durch beeinträchtigten Atherosklerose oder Hypercholesterolämie vasorelaxierenden Wirkung der Kranzarterien, unter Verwendung eines ACE-Inhibitors[1991/19]
English:Method for rehabilitating the vasorelaxant action of the coronary arteries impaired through atherosclerosis or hypercholesterolemia employing an ace inhibitor[1991/19]
French:Méthode pour restaurer l'activité vasorelaxante des artères coronaires, amoindrie par l'athérosclérose ou l'hypercholestérolémie, en utilisant un inhibiteur de l'ACE[1991/19]
File destroyed:03.03.2001
Examination procedure07.12.1992Examination requested  [1993/05]
13.05.1994Despatch of a communication from the examining division (Time limit: M06)
24.11.1994Application deemed to be withdrawn, date of legal effect  [1995/24]
17.01.1995Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [1995/24]
Fees paidRenewal fee
20.10.1992Renewal fee patent year 03
16.10.1993Renewal fee patent year 04
08.10.1994Renewal fee patent year 05
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Documents cited:Search[X]EP0219782  (HOECHST AG [DE]);
 [XP]EP0363671  (HOFFMANN LA ROCHE [CH]);
 [E]EP0425956  (SQUIBB & SONS INC [US]);
 [E]EP0426066  (SQUIBB & SONS INC [US]);
 [E]EP0411395  (THERA PATENT VERWALTUNGS GMBH [DE])
 [X]  - DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, vol. 113, no. 8, 26th February 1988, pages 300-302, DE; N. RIETBROCK et al.: "Antiischämische Wirksamkeit von Enalapril bei koronarer Herzkrankheit"
 [X]  - BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, vol. 28, suppl. 2, 13th October 1989, pages 151S-157S; P.J. SHULTZ et al.: "Effects of antihypertensive agents on endothelium-dependent and endothelium-independent relaxations"
 [X]  - AMERICAN JOURNAL OF PHYSIOLOGY, vol. 257, no. 4, part 2 of two parts, October 1989, pages H1315-H1320, US; J.L. MEHTA et al.: "Modulation of vascular tone by neutrophils: dependence on endothelial integrity"
 [X]  - NICHIDAI IGAKU ZASSHI, vol. 43, no. 11, 1984, pages 897-906, JP; T. OSADA: "Effects of diltiazem and captopril on blood pressure, humoral factors and the vascular system in spontaneously hypertensive rats"
 [X]  - CLINICAL CARDIOLOGY, vol. 11, no. 4, April 1988, pages 246-249; C. STROZZI et al.: "Ergometric evaluation of the effects of enalapril maleate in normotensive patients with stable angina"
 [X]  - JOURNAL OF HYPERTENSION SUPPLEMENT, vol. 3, suppl. 2, November 1985, pages 147-148; C. STROZZI et al.: "Ergometric evaluation of the effects of captopril in hypertensive patients with stable angina"
 [X]  - AMERICAN HEART JOURNAL, vol. 101, no. 1, January 1981, pages 22-31, US; N.A. AWAN et al.: "Efficacy of oral angiotensin-converting enzyme inhibition with captopril therapy in severe chronic normotensive congestive heart failure"
 [X]  - AMERICAN JOURNAL OF HYPERTENSION, vol. 1, no. 3, part 3, July 1988, pages 221S-223S, US; F.V. COSTA et al.: "Use of captopril to reduce serum lipids in hypertensive patients with hyperlipidemia"
 [X]  - THE TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, vol. 143, no. 1, May 1984, pages 127-128, JP; K. MIZUNO et al.: "Acute effect of captopril on serum lipid peroxides level in hypertensive patients"
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.