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Extract from the Register of European Patents

EP About this file: EP0454781

EP0454781 - RECOMBINANT CELLS FOR THERAPIES OF INFECTION AND HYPERPROLIFERATIVE DISORDERS AND PREPARATION THEREOF [Right-click to bookmark this link]
Former [1991/45]RECOMBINANT THERAPIES FOR INFECTION AND HYPERPROLIFERATIVE DISORDERS
[1998/51]
StatusNo opposition filed within time limit
Status updated on  22.10.1999
Database last updated on 11.09.2024
Most recent event   Tooltip06.08.2004Lapse of the patent in a contracting state
New state(s): LU		published on 22.09.2004  [2004/39]
Applicant(s)For all designated states
CHIRON CORPORATION
4560 Horton Street
Emeryville CA 94608-2916 / US
[N/P]
Former [1991/45]For all designated states
CHIRON CORPORATION
4560 Horton Street
Emeryville, California 94608 / US
Inventor(s)01 / GOLDSMITH, Mark, A.
20 Maple Street
West Roxbury, MA 02132 / US
02 / RALSTON, Robert, O.
2836 Judah
San Francisco, CA 94122 / US
[1991/45]
Representative(s)Goldin, Douglas Michael, et al
J.A. KEMP & CO. 14 South Square Gray's Inn
London WC1R 5JJ / GB
[N/P]
Former [1991/45]Goldin, Douglas Michael, et al
J.A. KEMP & CO. 14, South Square Gray's Inn
London WC1R 5LX / GB
Application number, filing date90902891.222.01.1990
[1991/45]
WO1990US00445
Priority number, dateUS1989030063723.01.1989         Original published format: US 300637
US1990046146117.01.1990         Original published format: US 461461
[1991/45]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9007936
Date:26.07.1990
Language:EN
[1990/17]
Type: A1 Application with search report 
No.:EP0454781
Date:06.11.1991
Language:EN
The application published by WIPO in one of the EPO official languages on 26.07.1990 takes the place of the publication of the European patent application.
[1991/45]
Type: B1 Patent specification 
No.:EP0454781
Date:16.12.1998
Language:EN
[1998/51]
Search report(s)International search report - published on:US26.07.1990
(Supplementary) European search report - dispatched on:EP15.05.1992
ClassificationIPC:A61K39/12, C07H15/12, C12N15/00, C12N5/00, C12N7/00
[1991/45]
CPC:
A61K31/70 (EP); A61P31/12 (EP); A61P35/00 (EP);
C12N15/85 (EP); Y02A50/30 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   IT,   LI,   LU,   NL,   SE [1991/45]
TitleGerman:REKOMBINANTE ZELLEN FÜR THERAPIEN VON INFEKTIONEN UND HYPERPROLIEFERATIVE STÖRUNGEN UND DEREN HERSTELLUNG[1998/51]
English:RECOMBINANT CELLS FOR THERAPIES OF INFECTION AND HYPERPROLIFERATIVE DISORDERS AND PREPARATION THEREOF[1998/51]
French:CELLULES DE RECOMBINAISON POUR DES THERAPIES D'INFECTIONS ET DE TROUBLES HYPERPROLIFERATIFS ET LA PREPARATION DE CES CELLULES[1998/51]
Former [1991/45]REKOMBINANTTHERAPIEN FÜR INFEKTIONEN UND HYPERPROLIFERATIVE STÖRUNGEN
Former [1991/45]RECOMBINANT THERAPIES FOR INFECTION AND HYPERPROLIFERATIVE DISORDERS
Former [1991/45]THERAPIES DE RECOMBINAISON POUR INFECTIONS ET TROUBLES HYPERPROLIFERATIFS
MiscellaneousEPB 1997/44: Teilanmeldung 97113730.2 eingereicht am 08/08/97
EPB 1997/44: Divisional application 97113730.2 filed on 08/08/97
EPB 1997/44: Demande divisionnaire 97113730.2 déposée le 08/08/97
Entry into regional phase09.08.1991National basic fee paid 
09.08.1991Search fee paid 
09.08.1991Designation fee(s) paid 
09.08.1991Examination fee paid 
Examination proceduredeletedDecision about request for accelerated examination - accepted: No
10.07.1990Request for preliminary examination filed
International Preliminary Examining Authority: DE
09.08.1991Examination requested  [1991/45]
12.12.1994Despatch of a communication from the examining division (Time limit: M08)
30.11.1995Reply to a communication from the examining division
13.05.1996Despatch of a communication from the examining division (Time limit: M02)
23.07.1996Reply to a communication from the examining division
19.12.1996Despatch of a communication from the examining division (Time limit: M04)
28.04.1997Reply to a communication from the examining division
28.04.1997Request for accelerated examination filed
25.11.1997Despatch of communication of intention to grant (Approval: No)
11.03.1998Despatch of communication of intention to grant (Approval: later approval)
25.05.1998Communication of intention to grant the patent
07.07.1998Fee for grant paid
07.07.1998Fee for publishing/printing paid
Divisional application(s)EP97113730.2  / EP0832980
Opposition(s)17.09.1999No opposition filed within time limit [1999/49]
Request for further processing for:30.11.1995Request for further processing filed
30.11.1995Full payment received (date of receipt of payment)
Request granted
18.12.1995Decision despatched
Fees paidRenewal fee
27.01.1992Renewal fee patent year 03
14.12.1992Renewal fee patent year 04
22.12.1993Renewal fee patent year 05
27.12.1994Renewal fee patent year 06
27.12.1995Renewal fee patent year 07
18.12.1996Renewal fee patent year 08
22.12.1997Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT16.12.1998
BE16.12.1998
ES16.12.1998
LU22.01.1999
DK16.03.1999
SE16.03.1999
[2004/39]
Former [2003/45]AT16.12.1998
BE16.12.1998
ES16.12.1998
DK16.03.1999
SE16.03.1999
Former [2002/25]AT16.12.1998
BE16.12.1998
ES16.12.1998
SE16.03.1999
Former [2001/23]AT16.12.1998
BE16.12.1998
SE16.03.1999
Former [1999/34]AT16.12.1998
BE16.12.1998
Former [1999/32]BE16.12.1998
Documents cited:Search[E]WO9011359  (WHITEHEAD BIOMEDICAL INST [US]);
 [E]WO9102805  (VIAGENE INC [US]);
 [E]EP0415731  (WELLCOME FOUND [GB]);
 [XP]EP0334301  (VIAGENE INC [US])
International search[Y]EP0288163  (US HEALTH [US]);
 [Y]US4738922  (HASELTINE WILLIAM A [US], et al)
 [Y]  - Proc. Natl. Acad. Sci. USA, Volume 85, published March 1988. J. PIERCE, et al. "Oligonucleotide that binds nuclear factor NF-Kappa beta acts as a lymphoid-specific and inducible enhancer element " pp. 1482-1486. see entire article.
 [Y]  - Science, Volume 231, published 11 January 1985. J. SODROSKI, et al. "Trans-activating transcriptional regulation of human T-cell leukemia virus type III long terminal repeat" pp. 171-173. see entire article.
 [Y]  - Proc. Natl. Acad. Sci. USA, Volume 84, published August 1987. J. Yee, et al. "Gene expression from transcriptionally disabled retroviral vectors" pp. 5197-5021. see entire article.
 [Y]  - Proc. Natl. Acad. Sci. USA, Volume 83, published May 1986. S. YU, et al. "Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells" pp. 3194-3198. see entire article.
 [Y]  - Proc. Natl. Acad. Sci. USA, Volume 85, published April 1988. R. PATARCA, et al. "rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1" pp. 2733-2737. see entire article.
 [Y]  - Nature, Volume 334, published 21 July 1988, V WALBOT et al. "Plant development and ribozymes for pathogens" pp. 196-197. see entire article.
 [Y]  - Cell, Volume 80, published 31 July 1987, R. PALMITER et al. "Cell lineage ablation in transgenic mice by cellspecific expression of a toxin gene" pp. 435-443. see entire article.
 [Y]  - Mol. and Cell. Biol. Volume 6, published August 1988, A. MILLER et al. "Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production" pp. 2895-2902. see entire article.
 [Y]  - Nature, Volume 325, published 26 February 1987, H. MITSUYA et al. "Strategies for antiviral therapy in AIDS" pp. 773-778. see entire article.
 [Y]  - J. of Infect. Dis., Volume 157, published March 1988, M. HIRSCH, "Azidothymidine" pp. 427-431. see entire article.
 [Y]  - Proc. Natl. Acad. Sci. USA, Volume 85, published September 1988, A. FRANKEL et al. "Dimerization of the tat protein from human immunodeficiency virus: a cysteine-rich peptide mimics the normal metallinked dimer interface" pp. 6297-6300. see entire article.
 [Y]  - Science, Volume 239, published 1988, B. FELBER et al, "A quantitative bioassay based on trans-activation" pp. 184-187. see entire article.
 [Y]  - Cell, Volume 44, published 28 March 1988, A. DAYTON et al. "The trans-activator gene of the human T cell lymphotropic virus type III is required for replication" pp. 941-947. see entire article.
 [Y]  - Mol. and Cell. Biol. Volume 7, published February 1987, R. CONE et al. "Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector" pp. 887-897. see entire article.
 [Y]  - Nature, Volume 335, published 29 September 1988, D. BALTIMORE, "Intracellular immunization" pp. 395-396. see entire article.
 [Y]  - Nature, Volume 335, published 29 September 1988 A. FRIEDMAN, et al. "Expression of a truncated viral trans-activator selectively impedes lytic infection by its cognate virus" pp. 452-454 see entire article.
 [Y]  - Nature, Volume 336, published 24 November 1988. S.L. MANSOUR, et al. "Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. pp. 348-352. see entire article.
 [Y]  - Cell, Volume 48, published 27 February 1987. M. MUESING, et al. "Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein" pp 691-701. see entire article.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.