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Extract from the Register of European Patents

EP About this file: EP0471709

EP0471709 - RUTHENIUM(III) COMPLEXES AS ANTINEOPLASTIC AGENTS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  30.09.1995
Database last updated on 25.09.2024
Most recent event   Tooltip23.12.1999Lapse of the patent in a contracting state
New state(s): LU
published on 09.02.2000 [2000/06]
Applicant(s)For all designated states
BOEHRINGER MANNHEIM ITALIA S.P.A.
Via S. Uguzzone, 5
20126 Milano / IT
[N/P]
Former [1992/09]For all designated states
BOEHRINGER MANNHEIM ITALIA S.P.A.
Via S. Uguzzone, 5
I-20126 Milano / IT
Inventor(s)01 / ALESSIO, Enzo
Via S.Uguzzone, 5
I-20126 Milano / IT
02 / MESTRONI, Giovanni
Via S.Uguzzone, 5
I-20126 Milano / IT
03 / PACOR, Sabrina
Via S.Uguzzone, 5
I-20126 Milano / IT
04 / SAVA, Gianni
Via S.Uguzzone, 5
I-20126 Milano / IT
05 / SPINELLI, Silvano
Via S.Uguzzone, 5
I-20126 Milano / IT
[1992/09]
Representative(s)Weber, Manfred, et al
Roche Diagnostics GmbH, Patent Department Pharma (TR-E) Sandhofener Strasse 116
68305 Mannheim / DE
[N/P]
Former [1992/09]Weber, Manfred, Dr., et al
c/o Boehringer Mannheim GmbH, Patentabteilung, Sandhoferstrasse 116
D-68298 Mannheim / DE
Application number, filing date90906961.902.05.1990
[1992/09]
WO1990EP00699
Priority number, dateIT1989002038505.05.1989         Original published format: IT 2038589
[1992/09]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9013553
Date:15.11.1990
Language:EN
[1990/26]
Type: A1 Application with search report 
No.:EP0471709
Date:26.02.1992
Language:EN
The application published by WIPO in one of the EPO official languages on 15.11.1990 takes the place of the publication of the European patent application.
[1992/09]
Type: B1 Patent specification 
No.:EP0471709
Date:30.11.1994
Language:EN
[1994/48]
Search report(s)International search report - published on:EP15.11.1990
ClassificationIPC:C07F15/00, A61K31/28
[1992/09]
CPC:
C07F15/0053 (EP,US)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   IT,   LI,   LU,   NL,   SE [1992/09]
TitleGerman:RUTHENIUM(III)-KOMPLEXE ALS ANTINEOPLASTISCHE MITTEL[1992/09]
English:RUTHENIUM(III) COMPLEXES AS ANTINEOPLASTIC AGENTS[1992/09]
French:COMPLEXES DE RUTHENIUM (III) EN TANT QU'AGENTS ANTINEOPLASTIQUES[1992/09]
Entry into regional phase29.10.1991National basic fee paid 
29.10.1991Designation fee(s) paid 
29.10.1991Examination fee paid 
Examination procedure22.11.1990Request for preliminary examination filed
International Preliminary Examining Authority: DE
29.10.1991Examination requested  [1992/09]
22.12.1992Despatch of a communication from the examining division (Time limit: M06)
25.06.1993Reply to a communication from the examining division
03.09.1993Despatch of communication of intention to grant (Approval: Yes)
21.04.1994Communication of intention to grant the patent
05.07.1994Fee for grant paid
05.07.1994Fee for publishing/printing paid
Opposition(s)31.08.1995No opposition filed within time limit [1995/47]
Fees paidRenewal fee
19.05.1992Renewal fee patent year 03
13.05.1993Renewal fee patent year 04
26.05.1994Renewal fee patent year 05
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipBE30.11.1994
DK30.11.1994
NL30.11.1994
SE28.02.1995
LU31.05.1995
[2000/06]
Former [1998/15]BE30.11.1994
DK30.11.1994
NL30.11.1994
SE28.02.1995
Former [1996/03]BE30.11.1994
NL30.11.1994
SE28.02.1995
Former [1995/41]BE30.11.1994
NL30.11.1994
Former [1995/35]NL30.11.1994
Cited inInternational search   [ ] - Canadian Journal of Chemistry, Volume 67, No. 3, March 1989, Toronto Press, (Canada), P.K.L. CHAN et al.: "Effects of Halide (X) and Sulfoxide (R2SO) Replacement within the Ruthenium (II) Nitroimidazole Complexes, RuX2(R2SO)m(Nitroimidazole)n, m = 1-3, n = 1 or 2: their Characterization, Solution Chemistry, Radiosensitizing Activity, and Related Properties", pages 508-516
    [ ] - CHEMICAL ABSTRACTS, Volume 110, 1989, (Columbus, Ohio, US), U.C. SARMA et al.: "Complexes of Ruthenium (III) with Dimethyl Sulfoxide I. (Ru2C16 (DMSO) 4), Fac and mer Isomers of (RuC13 (DMSO) 3): Versatile Starting Materials for the Synthesis of Ruthenium (III) Complexes", see page 791* Abstract 146531k, & Polyhedron 1988, 7(18), 1727-35 (Eng)*
    [ ] - CHEMICAL ABSTRACTS, Volume 112, 1990, (Columbus, Ohio, US), G. MESTRONI: "Chemical, Biological and Antitumor Properties of Ruthenium (II) Complexes with Dimethyl Sulfoxide", see page 29* Abstract 91321a & Prog. Clin. Biochem. Med. 1989, 10*
    [ ] - Journal of the Chemical Society, Dalton Transactions, 1973, I.P. EVANS et al.: "Dichlorotetrakis (Dimethyl Sulphoxide) Ruthenium (II) and its use as a Source Material for some new Ruthenium (II) Complexes, pages 204-209
    [ ] - CHEMICAL ABSTRACTS, Volume 86, 1977, (Columbus, Ohio, US), T. BORA et al.: "Some Dimethyl Sulfoxide and Sulfide Complexes of Ruthenium", see page 449* Abstract 50049u. J. Inorg. Nucl. Chem. 1976, 38(10), 1815-20 (Eng)*
Examination   - Journal of the Chemical Society, Dalton Transactions, 1973, I.P. Evans et al.: "Dichlorotetrakis (dimethyl sulphoxide) ruthenium (II) and its use as a source material for some new ruthenium (II) complexes", pages 204-209 see page 208, right-hand column, paragraph 4: "Nitrosyltrichlorobis (dimethyl sulphoxide) ruthenium (II)"
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