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Extract from the Register of European Patents

EP About this file: EP0451130

EP0451130 - Use of amiloride and other pyrazine derivatives for preventing or treating ocular neovascularization [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  26.07.1995
Database last updated on 28.06.2024
Most recent event   Tooltip26.07.1995Application deemed to be withdrawnpublished on 13.09.1995 [1995/37]
Applicant(s)For all designated states
CELTRIX PHARMACEUTICALS, INC.
3055 Patrick Henry Drive
Santa Clara, CA 95054-1815 / US
[1993/24]
Former [1991/41]For all designated states
BALTIMORE BIOTECH, INC.
St. Joeseph's Hospital, 7620 York Road
Towson, Maryland 21204 / US
Inventor(s)01 / Glaser, Bert M.
11201 Valley Heights Drive
Owings Mills, Maryland 21117 / US
02 / Varner, Hugh H.
318 Ringold Valley Circle
Cockeysville, Maryland 21030 / US
[1991/41]
Representative(s)Goldin, Douglas Michael, et al
J.A. KEMP & CO. 14 South Square Gray's Inn
London WC1R 5JJ / GB
[N/P]
Former [1993/24]Goldin, Douglas Michael, et al
J.A. KEMP & CO. 14, South Square Gray's Inn
London WC1R 5LX / GB
Former [1991/41]Colens, Alain
Rue Frans Merjay, 21
B-1060 Bruxelles / BE
Application number, filing date91870055.004.04.1991
[1991/41]
Priority number, dateUS1990050458405.04.1990         Original published format: US 504584
[1991/41]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0451130
Date:09.10.1991
Language:EN
[1991/41]
Type: A3 Search report 
No.:EP0451130
Date:05.08.1992
Language:EN
[1992/32]
Search report(s)(Supplementary) European search report - dispatched on:EP16.06.1992
ClassificationIPC:A61K31/495
[1991/41]
CPC:
A61K31/495 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1991/41]
TitleGerman:Verwendung von Amilorid und anderen Pyrazin-Derivaten zur Prophylaxe und Behandlung von Neovaskularisierung im Auge[1991/41]
English:Use of amiloride and other pyrazine derivatives for preventing or treating ocular neovascularization[1991/41]
French:Utilisation d'amiloride et d'autres dérivés de pyrazine dans la prévention et le traitement de néovascularisation oculaire[1991/41]
File destroyed:03.03.2001
Examination procedure04.02.1993Examination requested  [1993/16]
07.09.1994Despatch of a communication from the examining division (Time limit: M06)
18.03.1995Application deemed to be withdrawn, date of legal effect  [1995/37]
18.04.1995Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [1995/37]
Fees paidRenewal fee
25.03.1993Renewal fee patent year 03
11.04.1994Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
30.04.199505   M06   Not yet paid
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Documents cited:Search[X]WO9009792
 [YD]  - ANTICANCER RESEARCH, vol. 8, 1988, pages 1373-1376; J.A: KELLEN et al.: "Antimetastatic effect of amiloride in an animal tumour model"
 [YD]  - FEBS LETTERS, vol. 214, no. 1, 1987, pages 187-191, Elsevier Science Publishers B.V. (Biomedical Division); J.-D. VASSALLI et al.: "Amiloride selectively inhibits the urokinase-type plasminogen activator"
 [Y]  - INVEST. OPHTHALMOL. VIS. SCI., vol. 30, suppl., 1989, page 395, abstract no. 27; B.M. GLASER et al.: "A urokinase inhibitor derived from human RPE cells inhibits neovascularization in vivo"
 [YD]  - INVEST. OPHTHALMOL. VIS. SCI., vol. 22, no. 2, February 1982, pages 191-199, ASSOC. FOR RES. IN VIS. AND OPHTHAL., INC.; M. BERMAN et al.: "Plasminogen activator (urokinase) causes vascularization of the cornea"
 [XP]  - ARCH. OPHTHALMOL., vol. 108, no. 10, October 1990, pages 1474-1476; R.L. AVERY et al.: "Systemic amiloride inhibits experimentally induced neovascularization"
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.