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Extract from the Register of European Patents

EP About this file: EP0550528

EP0550528 - ACTIVE SITE OF INTERLEUKIN-8: POLYPEPTIDE ANALOGS AND ANTIBODIES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  04.01.1996
Database last updated on 31.08.2024
Most recent event   Tooltip04.01.1996Application deemed to be withdrawnpublished on 31.01.1996 [1996/05]
Applicant(s)For all designated states
THE SCRIPPS RESEARCH INSTITUTE
10666 North Torrey Pines Road
La Jolla, CA 92037 / US
[1993/28]
Inventor(s)01 / SCHRAUFSTATTER, Ingrid
4183 Corte de la Siena
San Diego, CA 92130-2106 / US
02 / COCHRANE, Charles
8038 La Jolla Scenic Drive North
La Jolla, CA 92037 / US
[1993/36]
Former [1993/28]01 / SCHRAUFSTATTER, Ingrid
8310 Regents Road
San Diego, CA 92122 / US
02 / COCHRANE, Charles
8038 La Jolla Scenic Drive North
La Jolla, CA 92037 / US
Representative(s)Fisher, Adrian John
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [1993/28]Fisher, Adrian John
CARPMAELS & RANSFORD 43 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date91916814.612.09.1991
[1993/28]
WO1991US06619
Priority number, dateUS1990058167312.09.1990         Original published format: US 581673
US1991075582406.09.1991         Original published format: US 755824
[1993/28]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9204372
Date:19.03.1992
Language:EN
[1992/07]
Type: A1 Application with search report 
No.:EP0550528
Date:14.07.1993
Language:EN
The application published by WIPO in one of the EPO official languages on 19.03.1992 takes the place of the publication of the European patent application.
[1993/28]
Search report(s)International search report - published on:US19.03.1992
(Supplementary) European search report - dispatched on:EP28.03.1994
ClassificationIPC:C07K7/08, A61K37/02, C12P21/08, G01N33/68, G01N33/577, A61K39/395
[1994/17]
CPC:
C07K16/244 (EP,US); A61K51/08 (EP,US); C07K14/5421 (EP,US);
A61K2039/505 (EP,US); C07K2317/34 (EP,US)
Former IPC [1993/28]C07K7/00, C07K15/00, A61K37/02
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1993/28]
TitleGerman:AKTIVES ZENTRUM VON INTERLEUKIN-8: POLYPEPTID-ANALOGA UND ANTIKÖRPER[1993/28]
English:ACTIVE SITE OF INTERLEUKIN-8: POLYPEPTIDE ANALOGS AND ANTIBODIES[1993/28]
French:SITE ACTIF D'INTERLEUKINE-8 : ANALOGUES POLYPEPTIDIQUES ET ANTICORPS[1993/28]
File destroyed:03.03.2001
Entry into regional phase13.04.1993National basic fee paid 
13.04.1993Search fee paid 
13.04.1993Designation fee(s) paid 
13.04.1993Examination fee paid 
Examination procedure26.03.1992Request for preliminary examination filed
International Preliminary Examining Authority: DE
13.04.1993Examination requested  [1993/28]
01.04.1995Application deemed to be withdrawn, date of legal effect  [1996/05]
26.06.1995Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [1996/05]
Request for further processing for:23.11.1994Request for further processing filed
24.11.1994Full payment received (date of receipt of payment)
Request granted
01.02.1995Decision despatched
Fees paidRenewal fee
13.04.1993Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
30.09.199404   M06   Not yet paid
30.09.199505   M06   Not yet paid
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]WO8908665  (US HEALTH [US]) [A] 1-14 * page 6; claim - *;
 [A]  - M. STICHERLING ET AL, "Production and characterization of monoclonal antibodies against the novel Neutrophil Activating Peptide NAP/IL-8", JOURNAL OF IMMUNOLOGY, BALTIMORE US, (19890901), vol. 143, no. 5, pages 1628 - 1634, XP000604924 [A] 3-5,9-12 * the whole document especially page 1634 *
 [A]  - E.J. MILLER ET AL, "Interleukin-8 (IL-8)-induced neutrophil chemotaxis is inhibited by synthetic peptides", FASEB JOURNAL, BETHESDA, MD US, (199006), vol. 4, page A2117 [A] 1,8 * abstract 2452 *
 [A]  - E.J. MILLER ET AL, "a synthetic peptide specifically inhibits Neutrophil Activating Factor-induced chemotaxis", AMERICAN REVIEW OF RESPIRATORY DISEASE, (199004), vol. 141, no. 4, page A95 [A] 8 * abstract *
 [A]  - S.TANAKA ET AL, "Synthesis and biological characterization of Monocyte-Derived Neutrophil Chemotactic Factor", FEBS LETTERS, AMSTERDAM NL, (198808), vol. 236, no. 2, doi:doi:10.1016/0014-5793(88)80078-4, pages 467 - 470, XP025601723 [A] 1,8 * the whole document *

DOI:   http://dx.doi.org/10.1016/0014-5793(88)80078-4
International search[XY]WO8904836  (SANDOZ AG [CH], et al)
 [XY]  - Journal Experimental Medicine, Vol. 167, issued June 1988, MATSUSHIMA et al., "Molecular Cloning of a Human Monocyte-Derived Neutrophil Chemotactic Factor (MDNCF) and the Induction of MDNCF mRNA by Interleukin 1 and Tumor Necrosis Factor", pages 1883-1893, see page 1886.
 [XY]  - Biochem. Biophys. Res. Comm., Vol. 151, No. 2, issued 15 March 1988, GREGORY et al., "Structure Determination of a Human Lymphocyte Derived Neutrophil Activating Peptide (LYNAP)", pages 883-890, see page 886.
 [XY]  - Molecular and Cellular Biology, Vol. 9, No. 5, issued May 1989, KOWALSKI et al., "Regulation of the mRNA of Monocyte-Derived Neutrophil-Activating Peptide in Differentiating HL60 Promyelocytes", pages 1946-1957, see page 1951.
 [Y]  - Clin. Chem., Vol. 27, No. 11, issued 1981, SEVIER et al., "Monoclonal Antibodies in Clinical Immunology", pages 1797-1806, see all.
 [Y]  - Journal Biological Chemistry, Vol. 264, No. 32, issued 15 November 1989, CLORE et al., "Determination of the Secondary Structure of Interleukin 8 by Nuclear Magnetic Resonance Spectroscopy", pages 18907-18911, see entire document.
 [Y]  - Biochemistry, Vol. 29, issued 20 February 1990, CLORE et al., "Three Dimensional Structure of Interleukin 8 in Solution", pages 1689-1696, see entire document.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.