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Extract from the Register of European Patents

EP About this file: EP0551427

EP0551427 - BETA-CAROTENE AND ASPIRIN THERAPY FOR INHIBITION OF MAJOR VASCULAR EVENTS [Right-click to bookmark this link]
Former [1993/29]BETA-CAROTENE AND VITAMIN E THERAPY FOR INHIBITION OF MAJOR VASCULAR EVENTS
[1999/29]
StatusThe application has been refused
Status updated on  20.04.2000
Database last updated on 02.11.2024
Most recent event   Tooltip20.04.2000Refusal of applicationpublished on 07.06.2000 [2000/23]
Applicant(s)For all designated states
BRIGHAM AND WOMEN'S HOSPITAL
75 Francis Street Boston
Massachusetts 02115 / US
[N/P]
Former [1993/29]For all designated states
BRIGHAM AND WOMEN'S HOSPITAL
75 Francis Street
Boston, Massachusetts 02115 / US
Inventor(s)01 / HENNEKENS, Charles, H.
2 Clark Road
Wellesley, MA 02181 / US
[1993/29]
Representative(s)Florence, Julia Anne, et al
Kilburn & Strode LLP
20 Red Lion Street
London WC1R 4PJ / GB
[N/P]
Former [1998/47]Florence, Julia Anne, et al
Kilburn & Strode, 20 Red Lion Street
London WC1R 4PJ / GB
Former [1993/29]Wright, Simon Mark, et al
Kilburn & Strode 30 John Street
London WC1N 2DD / GB
Application number, filing date91919463.927.09.1991
[1993/29]
WO1991US07093
Priority number, dateUS1990059202401.10.1990         Original published format: US 592024
[1993/29]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9205780
Date:16.04.1992
Language:EN
[1992/09]
Type: A1 Application with search report 
No.:EP0551427
Date:21.07.1993
Language:EN
The application published by WIPO in one of the EPO official languages on 16.04.1992 takes the place of the publication of the European patent application.
[1993/29]
Search report(s)International search report - published on:US16.04.1992
(Supplementary) European search report - dispatched on:EP02.08.1993
ClassificationIPC:A61K31/07, A61K31/605
[1999/29]
CPC:
A61K31/355 (EP,US); A61K31/07 (EP,KR,US); A61K31/015 (EP,US);
A61K31/60 (EP,US); A61P9/00 (EP); A61P9/08 (EP);
A61P9/10 (EP) (-)
C-Set:
A61K31/355, A61K2300/00 (US,EP);
A61K31/355, A61K31/015 (EP,US);
A61K31/60, A61K2300/00 (US,EP);
A61K31/60, A61K31/015 (US,EP)
Former IPC [1993/29]A61K31/07, A61K31/355, A61K31/605
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1993/29]
TitleGerman:THERAPIE AUF BASIS VON BETA-KAROTIN UND ASPIRIN ZUR HEMMUNG GROSSER VASKULÄRER ZWISCHENFÄLLE[1999/29]
English:BETA-CAROTENE AND ASPIRIN THERAPY FOR INHIBITION OF MAJOR VASCULAR EVENTS[1999/29]
French:THERAPIE A BASE DE BETA-CAROTENE ET D'ASPIRINE DESTINEE A PREVENIR LES ACCIDENTS VASCULAIRES MAJEURS[1999/29]
Former [1993/29]THERAPIE AUF BASIS VON BETA-KAROTIN UND VITAMIN E ZUR HEMMUNG GROSSER VASKULÄRER ZWISCHENFÄLLE
Former [1993/29]BETA-CAROTENE AND VITAMIN E THERAPY FOR INHIBITION OF MAJOR VASCULAR EVENTS
Former [1993/29]THERAPIE A BASE DE BETA-CAROTENE ET DE VITAMINE E DESTINEE A PREVENIR LES ACCIDENTS VASCULAIRES MAJEURS
Entry into regional phase26.04.1993National basic fee paid 
26.04.1993Search fee paid 
26.04.1993Designation fee(s) paid 
26.04.1993Examination fee paid 
Examination procedure30.04.1992Request for preliminary examination filed
International Preliminary Examining Authority: FR
26.04.1993Examination requested  [1993/29]
06.03.1997Despatch of a communication from the examining division (Time limit: M06)
15.12.1997Reply to a communication from the examining division
24.02.1998Despatch of a communication from the examining division (Time limit: M06)
07.10.1998Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
16.12.1998Reply to a communication from the examining division
02.08.1999Despatch of communication of intention to grant (Approval: )
17.01.2000Despatch of communication that the application is refused, reason: formalities examination [2000/23]
27.01.2000Application refused, date of legal effect [2000/23]
Request for further processing for:16.12.1998Request for further processing filed
16.12.1998Full payment received (date of receipt of payment)
Request granted
13.01.1999Decision despatched
15.12.1997Request for further processing filed
15.12.1997Full payment received (date of receipt of payment)
Request deemed not to be filed
08.01.1998Decision despatched
Fees paidRenewal fee
16.09.1993Renewal fee patent year 03
08.09.1994Renewal fee patent year 04
08.09.1995Renewal fee patent year 05
12.09.1996Renewal fee patent year 06
10.09.1997Renewal fee patent year 07
09.09.1998Renewal fee patent year 08
03.09.1999Renewal fee patent year 09
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Documents cited:Search[X]WO9010440  (HARVARD COLLEGE [US])
 [A]  - MED. NUTR. vol. 26, no. 1, 1990, pages 35 - 37 'Vitamines antioxydantes et beta-carotène: activités préventives en pathologie humaine.'
 [A]  - BIBL. NUTR. DIETA vol. 37, 1986, pages 53 - 91 K.F. GEY 'On the antioxidant hypothesis with regard to arteriosclerosis'
International search[Y]  - BURTON et al., "Beta-Carotene: An Unusual Type of Lipid Antioxidant", Science, Volume 224, 11 May 1984, see pages 569-573.
 [Y]  - PARTHASARATHY et al., "Probucol Inhibits Oxidative Modification of Low Density Lipoproteins", J. Clinical Invest., Volume 77, February 1986, see pages 641-644.
 [Y]  - STEINBERG et al., "Modifications of Low-Density Lipoproteins That Increase Its Atherogenicity", New England Journal of Medicine, Volume 320, No. 14, 06 April 1989, see pages 915-924.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.