Extract from the Register of European Patents

EP About this file: EP0545344

EP0545344 - Endothelin,converting enzymes [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.03.1998
Database last updated on 28.03.2026
Most recent event   Tooltip06.03.1998No opposition filed within time limitpublished on 22.04.1998 [1998/17]
Applicant(s)For all designated states
NISSHIN FLOUR MILLING CO., LTD.
19-12, Nihonbashi-koami-cho
Chuo-ku, Tokyo 103 / JP
[1993/23]
Inventor(s)01 / Ohwaki, Tatsuya, Kohpo-Hanafusa 203
1228-22, Kamekubo, Ohimachi
Iruma-gun, Saitama-ken / JP
02 / Sakai, Hiroshi
Takayama-mansion 303, 17-10, Tsurugaoka 1-chome
Ohimachi, Iruma-gun, Saitama-ken / JP
[1993/23]
Representative(s)Gille Hrabal Partnerschaftsgesellschaft mbB Patentanwälte
Brucknerstraße 20
40593 Düsseldorf / DE
[N/P]
Former [1993/23]Türk, Gille, Hrabal, Leifert
Brucknerstrasse 20
D-40593 Düsseldorf / DE
Application number, filing date92120430.130.11.1992
[1993/23]
Priority number, dateJP1991031687429.11.1991         Original published format: JP 31687491
[1993/23]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0545344
Date:09.06.1993
Language:EN
[1993/23]
Type: A3 Search report 
No.:EP0545344
Date:16.02.1994
Language:EN
[1994/07]
Type: B1 Patent specification 
No.:EP0545344
Date:02.05.1997
Language:EN
[1997/18]
Search report(s)(Supplementary) European search report - dispatched on:EP29.12.1993
ClassificationIPC:C12N9/64
[1994/07]
CPC:
C12N9/6497 (EP,US); C12Y304/24071 (EP,US)
Former IPC [1993/23]C12N9/00
Designated contracting statesCH,   DE,   FR,   GB,   IT,   LI,   SE [1993/23]
TitleGerman:Endothelin-konvertierende Enzyme[1993/23]
English:Endothelin,converting enzymes[1993/23]
French:Enzymes de conversion d'endothéline[1993/23]
Examination procedure13.10.1993Examination requested  [1993/49]
27.08.1996Despatch of communication of intention to grant (Approval: Yes)
29.10.1996Communication of intention to grant the patent
22.01.1997Fee for grant paid
22.01.1997Fee for publishing/printing paid
Opposition(s)03.02.1998No opposition filed within time limit [1998/17]
Fees paidRenewal fee
23.11.1994Renewal fee patent year 03
22.11.1995Renewal fee patent year 04
23.11.1996Renewal fee patent year 05
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Documents cited:Search[X]   J. TAKADA ET AL: "Phosphoramidon-sensitive endothelin-converting enzyme in the cytosol of cultured bovine endothelial cells", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 176, no. 2, 30 April 1991 (1991-04-30), DULUTH, MINNESOTA US, pages 860 - 865 [X] 1-5,10-13,15,16 * the whole document *
 [X]   Y. HIOKI ET AL: "Endothelin converting enzyme of bovine carotid artery smooth muscles", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 174, no. 2, 31 January 1991 (1991-01-31), DULUTH, MINNESOTA US, pages 446 - 451 [X] 1-5,10-13 * the whole document *
 [DX]   K. OKADA ET AL: "Conversion of big endothelin-1 by membrane-bound metalloendopeptidase in cultured bovine endothelial cells", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 171, no. 3, 28 September 1990 (1990-09-28), DULUTH, MINNESOTA US, pages 1192 - 1198 [DX] 1-5 * the whole document *
 [X]   T. MARSELLE ET AL: "Identification of a neutral metalloendopeptidase endothelin converting enzyme from various cultured endothelial cell lines", FASEB JOURNAL, vol. 5, no. 5, April 1991 (1991-04-01), BETHESDA, MD US, pages A1417 [X] 1-5 *abstract 6072*
 [X]   Y. MATSUMURA ET AL: "Conversion of big endothelin-1 to endothelin-1 by two types of metalloproteinases derived from porcine aortic endothelial cells", FEBS LETTERS., vol. 272, no. 1,2, October 1990 (1990-10-01), AMSTERDAM NL, pages 166 - 170 [X] 1-5 * the whole document *
 [PX]   CHEMICAL ABSTRACTS, vol. 117, no. 23, 7 December 1992, Columbus, Ohio, US; abstract no. 229115, H. SAKAI AND T. OOWAKI: "Purification of human endothelin-converting enzyme" page 389; [PX] 1-5,10-17 * abstract *
 [PX]   K. AHN ET AL: "The endothelin-converting enzyme from human umbilical vein is a membrane-bound metalloprotease similar to that from bovine aortic endothelial cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA., vol. 89, September 1992 (1992-09-01), WASHINGTON US, pages 8606 - 8610 [PX] 1-5 * the whole document *
 [PX]   T. OPGENORTH ET AL: "Endothelin-converting enzymes", FASEB JOURNAL., vol. 6, June 1992 (1992-06-01), BETHESDA, MD US, pages 2653 - 2659 [PX] 1-5 * the whole document *
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