| EP0555385 - AGENTS AND METHODS FOR BINDING TO ELAM-1 [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 27.08.1999 Database last updated on 28.03.2026 | Most recent event Tooltip | 27.08.1999 | Application deemed to be withdrawn | published on 13.10.1999 [1999/41] | Applicant(s) | For all designated states THE REGENTS OF THE UNIVERSITY OF MICHIGAN 475 East Jefferson, Room 2354 Ann Arbor, Michigan 48109-1248 / US | [N/P] |
| Former [1993/33] | For all designated states THE REGENTS OF THE UNIVERSITY OF MICHIGAN 475 East Jefferson, Room 2354 Ann Arbor, Michigan 48109-1248 / US | Inventor(s) | 01 /
LOWE, John, B. 3055 Whisperwood Drive, 383 Ann Arbor, MI 48105 / US | 02 /
MARKS, Rory, M. 2017 Ferdon Street Ann Arbor, MI 48104 / US | 03 /
STOOLMAN, Lloyd, M. 5201 Birkdale Ann Arbor, MI 48103 / US | [1993/33] | Representative(s) | des Termes, Monique, et al BREVALEX 3, rue du Docteur Lancereaux 75008 Paris / FR | [N/P] |
| Former [1993/33] | Des Termes, Monique, et al c/o Société de Protection des Inventions 25, rue de Ponthieu F-75008 Paris / FR | Application number, filing date | 92900499.2 | 25.10.1991 | [1993/33] | WO1991US07678 | Priority number, date | US19900603018 | 25.10.1990 Original published format: US 603018 | [1993/33] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9207572 | Date: | 14.05.1992 | Language: | EN | [1992/11] | Type: | A1 Application with search report | No.: | EP0555385 | Date: | 18.08.1993 | Language: | EN | The application published by WIPO in one of the EPO official languages on 14.05.1992 takes the place of the publication of the European patent application. | [1993/33] | Search report(s) | International search report - published on: | US | 14.05.1992 | (Supplementary) European search report - dispatched on: | EP | 07.02.1996 | Classification | IPC: | C07H3/06, C07H13/04, C07H15/04, A61K31/70, A61K48/00, A61K35/14, A61K49/00, C12N5/10, A61K9/127 | [1996/12] | CPC: |
C07H13/04 (EP);
A61K38/45 (EP);
A61K47/6425 (EP);
A61K47/6911 (EP);
A61K49/0002 (EP);
A61K49/0004 (EP);
A61K49/1812 (EP);
A61K9/1271 (EP);
A61P11/16 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
C07H15/04 (EP);
A61K48/00 (EP)
(-)
|
| Former IPC [1995/35] | C07H3/06, C07H13/04, C07H15/04, A61K31/70, A61K48/00, A61K35/14, A61K49/00, C12N5/10 | ||
| Former IPC [1993/33] | A61K31/73, C07H15/04, C07H5/06, C12N5/10 | Designated contracting states | AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LI, LU, NL, SE [1993/33] | Title | German: | SUBSTANZEN UND METHODEN ZUR BINDUNG AN ELAM-1 | [1993/33] | English: | AGENTS AND METHODS FOR BINDING TO ELAM-1 | [1993/33] | French: | AGENTS ET PROCEDES DE LIAISON A L'ELAM-1 | [1993/33] | Biological material | This application mentions deposited biological material, check the file for details | Entry into regional phase | 30.04.1993 | National basic fee paid | 30.04.1993 | Search fee paid | 30.04.1993 | Designation fee(s) paid | 30.04.1993 | Examination fee paid | Examination procedure | 19.05.1992 | Request for preliminary examination filed International Preliminary Examining Authority: DE | 03.05.1993 | Examination requested [1993/33] | 24.03.1998 | Despatch of a communication from the examining division (Time limit: M06) | 21.09.1998 | Reply to a communication from the examining division | 06.10.1998 | Despatch of a communication from the examining division (Time limit: M06) | 17.04.1999 | Application deemed to be withdrawn, date of legal effect [1999/41] | 17.05.1999 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [1999/41] | Fees paid | Renewal fee | 11.10.1993 | Renewal fee patent year 03 | 19.09.1994 | Renewal fee patent year 04 | 25.09.1995 | Renewal fee patent year 05 | 16.09.1996 | Renewal fee patent year 06 | 26.09.1997 | Renewal fee patent year 07 | 05.10.1998 | Renewal fee patent year 08 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X] M. M. PALCIC ET AL.: "Enzymic synthesis of oligosaccharides terminating in the tumor-associated sialyl-Lewis-a determinant.", CARBOHYDRATE RESEARCH, vol. 190, no. 1, 1 July 1989 (1989-07-01), AMSTERDAM NL, pages 1 - 11 [X] 1-3,12 * page 1 - page 7 * | [X] P. STANLEY AND P. H. ATKINSON: "The LEC11 chinese hamster ovary mutant synthesizes N-linked carbohydrates containing sialylated, fucosylated lactosamine units. Analysis by one and two-dimensional 1H NMR spectroscopy.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 263, no. 23, 15 August 1988 (1988-08-15), MD US, pages 11374 - 11381 [X] 1-3,12 * page 11374 - page 11375 * | [PX] A. KAMEYAMA ET AL.: "Synthetic studies on sialoglycoconjugates 22: total synthesis of tumor associated ganglioside, sialyl Lewis X.", JOURNAL OF CARBOHYDRATE CHEMISTRY, vol. 10, no. 4, pages 549 - 560 [PX] 1-3,12 * page 551 - page 552 * | International search | [X] The Journal of Biological Chemistry, Vol. 259, No. 14, issued 25 July 1984, LAMBLIN et al., "Primary Structure Determination of Five Sialylated Oligosaccharides Derived from Bronchial Mucus Glycoproteins of Patients Suffering from Cystic Fibrosis", pages 9051-9058, see entire document. [X] | [X] Cancer Research, Vol. 44, issued November 1984, FUKUSHIMA et al., "Characterization of Sialosylated Lewis X as New Tumor-Associated Antigen", pages 5279-5285, see entire document. [X] | [X] European Journal of Biochemistry, Vol. 177, No. 2, issued November 1988, VAN HALBEEK et al., "Isolalation and Structural Characterization of Low-molecular-mass Monosialyl Oligosaccharides Derived from Respiratory-mucus Glycoproteins of a Patient Suffering from Bronchiectasis", pages 443-460, see entire document. [X] | [X] Chemistry and Physics of Lipids, Vol. 42, issued 1986, HAKOMORI, "Tumor-associated Glycolipid Antigens, Their Metabolism and Organization", pages 209-233, see entire document. [X] | [XP] Proceedings of the National Academy of Sciences, (USA), Vol. 88, issued February 1991, TIEMEYER et al., "Carbohydrate Ligands for Endothelial-leukocyte Adhesion Molecule 1", pages 1138-1142, see entire document. [XP] | [XP] Biochemical Society Transactions, Vol. 19, No. 3, issued August 1991, LOWE et al., "A Transfected Human Fucosyltransferase cDNA Determines Biosynthesis of Oligosaccharide Ligand(s) for Endothelial-leukocyte Adhesion Molecule 1", pages 649-653, see entire document. [XP] | [XP] The Journal of Biologica Chemistry, Vol. 266, No. 23, issued 15 August 1991, BERG et al., "A Carbohydrate Domain Common to both Sialyl Le A and Sialyl Le X is Recognized by the Endothelial Cell Leudocyte Adhesion Molecule ELAM-1", pages 14869-14872, see entire document. [XP] | [AP] The Journal of Cell Biology, Vol. 115, No. 2, issued October 1991, ZHOU et al., "The Selectin GMP-140 Binds to Sialylated, Fucosylated Lactosaminoglycans on both Myeloid and Nonmyeloid Cells", pages 557-564. [AP] | [XP] Cell, Vol. 63, issued 21 December 1990, GOELZ et al., "ELFT: A Gene that Directs the Expression of an ELAM-1 Ligand", pages 1349-1356, see entire document. [XP] | [XP] Science, Vol. 250, issued 23 November 1990, WALZ et al., "Recognition by ELAM-1 of the Sialyl-Le X Determinant on Myeloid and Tumor Cells", pages 1132-1135, see entire document. [XP] | [XP] Science, Vol. 250, issued 23 November 1990, PHILLIPS et al., "ELAM-1 Mediates Cell Adhesion by Recognition of a Carbohydrate Ligand, Sialyl-Le X", pages 1130-1132, see entire document. [XP] | [X] Proceedings of the National Academy of Sciences (USA), Vol. 87, issued March 1990, HESSION et al., "Endothelial Leukocyte Adhesion Molecule 1: Direct Expressions Cloning and Functional Interactions", pages 1673-1677, see entire document. [X] | [AP] Biochemical and Biophysical Research Communications, Vol. 179, No. 2, issued 16 September 1991, TAKADA et al., "Adhesion of Human Cancer Cells to Vascular Endothelium Mediated by a Carbohydrate Antigen, Sialyl Lewis A", pages 713-719, see entire document. [AP] | [T] The Journal of Experimental Medicine, Vol. 174, issued December 1991, BERG et al., "The Cutaneous Lymphocyte Antigen In a Skin Lymphocyte Homing Receptor for the Vascular Lectin Endothelial Cell-Leukocyte Adhesion Molecule 1", pages 1461-1466, see entire document. [T] |