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EP About this file: EP0589930

EP0589930 - GABA-A RECEPTOR SUBUNITS ($g(a)-2, $g(a)-3, $g(a)-5, $g(a)-6, $g(b)-2) AND TRANSFECTED CELLS EXPRESSING THEM [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 19.01.2004 Database last updated on 06.07.2024
Most recent event Tooltip	07.12.2007	Lapse of the patent in a contracting state New state(s): IT	published on 09.01.2008 [2008/02]
Applicant(s)	For all designated states MERCK SHARP & DOHME LTD. Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB
	[N/P]
Former [2003/11]	For all designated states MERCK SHARP & DOHME LTD. Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB
Former [1994/14]	For all designated states MERCK SHARP & DOHME LTD. Hertford Road Hoddesdon Hertfordshire EN11 9BU / GB
Inventor(s)	01 / HADINGHAM, Karen Louise 83 Cambridge Road Sawbridgeworth, Hertfordshire CM21 9BU / GB
	02 / LE BOURDELLES, Beatrice 100 Herons Wood Harlow, Essex CM20 1RT / GB
	03 / WHITING, Paul John Tithe Barn, Bentfield Green Stansted Mountfitchet, Essex CM24 8HX / GB
	04 / WINGROVE, Peter Baxter Fairgreen House Sawbridgeworth, Hertfordshire CM21 9AJ / GB
	[1994/14]
Representative(s)	Thompson, John, et al Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR / GB
	[N/P]
Former [1994/14]	Thompson, John Dr., et al Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR / GB
Application number, filing date	92911528.5	09.06.1992
	[1994/14]
	WO1992GB01031
Priority number, date	GB19910012504	11.06.1991 Original published format: GB 9112504
	[2002/43]
Former [1994/14]	GB19910125047	11.06.1991
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9222652
	Date:	23.12.1992
	Language:	EN
	[1992/32]
	Type:	A1 Application with search report
	No.:	EP0589930
	Date:	06.04.1994
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 23.12.1992 takes the place of the publication of the European patent application.
	[1994/14]
	Type:	B1 Patent specification
	No.:	EP0589930
	Date:	12.03.2003
	Language:	EN
	[2003/11]
Search report(s)	International search report - published on:	EP	23.12.1992
Classification	IPC:	C12N15/12, C07K14/00, C12P21/02	[2003/11]
	CPC:	C07K14/70571 (EP); A61K38/00 (EP)
	Former IPC [1994/14]	C12N15/12, C07K13/00, C12P21/02
Designated contracting states	AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LI, LU, NL, SE [1994/14]
Title	German:	GABA-A REZEPTORUNTEREINHEITEN (ALPHA-2, ALPHA-3, ALPHA-5, ALPHA-6, BETA-2) UND TRANSFEKTIERTE ZELLEN, DIE DIESE EXPREMIEREN	[1994/14]
	English:	GABA-A RECEPTOR SUBUNITS ($g(a)-2, $g(a)-3, $g(a)-5, $g(a)-6, $g(b)-2) AND TRANSFECTED CELLS EXPRESSING THEM	[1994/14]
	French:	SOUS-UNITES ($g(a)-2, $g(a)-3, $g(a)-5, $g(a)-6, $g(b)-2) DE RECEPTEUR DE GABA-A ET CELLULES TRANSFECTEES LES EXPRIMANT	[1994/14]
Entry into regional phase	13.10.1993	National basic fee paid
	13.10.1993	Designation fee(s) paid
	13.10.1993	Examination fee paid
Examination procedure	17.12.1992	Request for preliminary examination filed International Preliminary Examining Authority: DE
	13.10.1993	Examination requested [1994/14]
	12.05.1998	Despatch of a communication from the examining division (Time limit: M06)
	23.11.1998	Reply to a communication from the examining division
	16.04.1999	Despatch of a communication from the examining division (Time limit: M06)
	26.10.1999	Reply to a communication from the examining division
	09.12.1999	Despatch of a communication from the examining division (Time limit: M06)
	26.05.2000	Reply to a communication from the examining division
	05.02.2001	Despatch of a communication from the examining division (Time limit: M04)
	15.05.2001	Reply to a communication from the examining division
	08.02.2002	Despatch of communication of intention to grant (Approval: Yes)
	19.08.2002	Communication of intention to grant the patent
	29.11.2002	Fee for grant paid
	29.11.2002	Fee for publishing/printing paid
Divisional application(s)	EP02078136.5 / EP1258530
Opposition(s)	15.12.2003	No opposition filed within time limit [2004/10]
Fees paid	Renewal fee
	07.04.1994	Renewal fee patent year 03
	30.06.1995	Renewal fee patent year 04
	01.07.1996	Renewal fee patent year 05
	30.06.1997	Renewal fee patent year 06
	30.06.1998	Renewal fee patent year 07
	30.06.1999	Renewal fee patent year 08
	30.06.2000	Renewal fee patent year 09
	02.07.2001	Renewal fee patent year 10
	01.07.2002	Renewal fee patent year 11
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	AT	12.03.2003
	BE	12.03.2003
	GR	12.03.2003
	IT	12.03.2003
	NL	12.03.2003
	LU	09.06.2003
	SE	12.06.2003
	[2008/02]
Former [2004/39]	AT	12.03.2003
	BE	12.03.2003
	GR	12.03.2003
	NL	12.03.2003
	LU	09.06.2003
	SE	12.06.2003
Former [2004/10]	AT	12.03.2003
	BE	12.03.2003
	GR	12.03.2003
	NL	12.03.2003
	SE	12.06.2003
Former [2003/50]	AT	12.03.2003
	GR	12.03.2003
	NL	12.03.2003
	SE	12.06.2003
Former [2003/47]	AT	12.03.2003
	GR	12.03.2003
	NL	12.03.2003
Former [2003/46]	GR	12.03.2003
	NL	12.03.2003
Former [2003/41]	NL	12.03.2003
Cited in	International search	[X] - NATURE. vol. 335, 1 September 1988, LONDON GB pages 76 - 79; LEVITAN, EDWIN S.; SCHOFIELD, PETER R.; BURT, DAVID R.; RHEE, LUCY M.; WISDEN, WILLIAM; KOHLER, MARTIN; FUJITA, NORIHISA ET AL.: 'Structural and functional basis for GABAA receptor heterogeneity.' cited in the application
		[X] - NATURE. vol. 346, 16 August 1990, LONDON GB pages 648 - 651; LUEDDENS, HARTMUT; PRITCHETT, DOLAN B.; KOEHLER, MARTIN; KILLISCH, IRIS; KEINAENEN, KARI; MONYER, HANNAH; SPRENGEL, ROLF; SEEBURG,: 'Cerebellar GABAA receptor selective for a behavioral alcohol antagonist.' cited in the application
		[X] - EMBO JOURNAL. vol. 8, no. 6, 1989, EYNSHAM, OXFORD GB pages 1665 - 1670; YMER, SANIE; SCHOFIELD, PETER R.; DRAGUHN, ANDREAS; WERNER, PIA; KOEHLER, MARTIN; SEEBURG, PETER H.: 'GABAA receptor .beta. subunit heterogeneity: functional expression of cloned cDNAs.' cited in the application

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