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Extract from the Register of European Patents

EP About this file: EP0627932

EP0627932 - ANTIBODY CONSTRUCT [Right-click to bookmark this link]
Former [1994/50]NOVEL ANTIBODY CONSTRUCT
[2000/15]
StatusNo opposition filed within time limit
Status updated on  14.03.2003
Database last updated on 11.09.2024
Most recent event   Tooltip14.03.2003No opposition filed within time limitpublished on 02.05.2003  [2003/18]
Applicant(s)For all designated states
City of Hope
1500 East Duarte Road
Duarte, CA 91010 / US
[N/P]
Former [1994/50]For all designated states
CITY OF HOPE
1500 East Duarte Road
Duarte California 91010-0269 / US
Inventor(s)01 / WU, Anna, M.
14919 Sutton Street
Sherman Oaks, CA 91403 / US
[1994/50]
Representative(s)Hall, Marina, et al
Elkington and Fife Prospect House, 8 Pembroke Road Sevenoaks
Kent TN13 1XR / GB
[N/P]
Former [1995/05]Dowden, Marina, et al
Elkington and Fife Prospect House, 8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
Former [1995/01]Marchant, James Ian
Elkington and Fife Prospect House 8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
Former [1994/50]Sheard, Andrew Gregory
Kilburn & Strode 30, John Street
London WC1N 2DD / GB
Application number, filing date92924181.804.11.1992
[1994/50]
WO1992US09347
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9409817
Date:11.05.1994
Language:EN
[1994/11]
Type: A1 Application with search report 
No.:EP0627932
Date:14.12.1994
Language:EN
The application published by WIPO in one of the EPO official languages on 11.05.1994 takes the place of the publication of the European patent application.
[1994/50]
Type: B1 Patent specification 
No.:EP0627932
Date:08.05.2002
Language:EN
[2002/19]
Search report(s)International search report - published on:US11.05.1994
(Supplementary) European search report - dispatched on:EP19.03.1997
ClassificationIPC:C12N15/13, C07K16/46, C07K16/30, C12N1/21
[2000/13]
CPC:
C07K16/468 (EP,US); C07K16/00 (EP,US); C07K16/3007 (EP,US);
Y10S530/866 (EP,US); Y10S530/867 (EP,US)
Former IPC [1994/50]A61K39/00, C12P21/06, C12N5/00, C12N1/00, C12N15/00, C07K3/00, C07K13/00, C07K15/00, C07K17/00
Designated contracting statesDE,   FR,   GB [1994/50]
TitleGerman:ANTIKÖRPERKONSTRUKTE[2000/15]
English:ANTIBODY CONSTRUCT[2000/15]
French:STRUCTURE D'ANTICORPS[2000/15]
Former [1994/50]NEUARTIGE ANTIKÖRPERKONSTRUKTE
Former [1994/50]NOVEL ANTIBODY CONSTRUCT
Former [1994/50]NOUVELLE STRUCTURE D'ANTICORPS
Entry into regional phase01.08.1994National basic fee paid 
01.08.1994Search fee paid 
01.08.1994Designation fee(s) paid 
01.08.1994Examination fee paid 
Examination procedure01.08.1994Examination requested  [1994/50]
08.03.1999Despatch of a communication from the examining division (Time limit: M06)
07.09.1999Reply to a communication from the examining division
08.06.2000Despatch of a communication from the examining division (Time limit: M06)
03.11.2000Reply to a communication from the examining division
19.07.2001Despatch of communication of intention to grant (Approval: Yes)
14.11.2001Communication of intention to grant the patent
06.02.2002Fee for grant paid
06.02.2002Fee for publishing/printing paid
Opposition(s)11.02.2003No opposition filed within time limit [2003/18]
Fees paidRenewal fee
15.11.1994Renewal fee patent year 03
09.11.1995Renewal fee patent year 04
11.11.1996Renewal fee patent year 05
10.11.1997Renewal fee patent year 06
10.11.1998Renewal fee patent year 07
12.11.1999Renewal fee patent year 08
13.11.2000Renewal fee patent year 09
14.11.2001Renewal fee patent year 10
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]EP0506124  (TANOX BIOSYSTEMS INC [US]) [X] 8,12 * page 10 *;
 [A]  - COLCHER D ET AL, "IN VIVO TUMOR TARGETING OF A RECOMBINANT SINGLE-CHAIN ANTIGEN-BINDING PROTEIN", JOURNAL OF THE NATIONAL CANCER INSTITUTE, (19900718), vol. 82, no. 14, pages 1191 - 1197, XP000574245 [A] 1-14

DOI:   http://dx.doi.org/10.1093/jnci/82.14.1191
 [A]  - P.PACK AND A.PLÜCKTHUN, "Miniantibodies: Use of amphipatic helices to produce functional, flexibly linked dimeric Fv fragments with high avidity in Escherichia coli", BIOCHEMISTRY, EASTON, PA US, (19920218), vol. 31, no. 6, pages 1579 - 1584, XP002026334 [A] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1021/bi00121a001
 [A]  - A.J.CUMBER ET AL., "Comparative stabilities in vitro and in vivo of a recombinant mouse antibody FvCys fragment and a bisFvCys conjugate", JOURNAL OF IMMUNOLOGY, BALTIMORE US, (19920701), vol. 149, no. 1, pages 120 - 126, XP002026335 [A] 1-14 * the whole document *
 [T]  - S-Z HU ET AL., "Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment ( single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts", CANCER RESEARCH, MD US, (19960701), vol. 56, no. 13, pages 3055 - 3061, XP002026337 [T] 1-14 * the whole document *
International search[XY]  - Cancer Research, Volume 51, issued 01 December 1991, MILENIC et al.: "Construction, Binding Properties, Metabolism, and Tumor Targeting of a Single-Chain Fv Derived from the Pancarcinoma Monoclonal Antibody CC49", pages 6363-6371, see entire document.
 [Y]  - Proceedings of the National Academy of Sciences, Volume 81, issued November 1984, MORRISON et al.: "Chimeric Human Antibody Molecules: Mouse Antigen-Binding Domains with Human Constant Region Domains", pages 6851-6855, see entire document.
 [Y]  - Science, Volume 242, issued 21 October 1988, BIRD et al.: "Single-Chain Antigen-Binding Proteins", pages 423-426, see entire document.
 [Y]  - Human Antibodies and Hybridomas, Volume 1, No. 1, issued 1990, GILLIES et al.: "Antigen Binding and Biological Activities of Engineered Mutant Chimeric Antibodies with Human Tumor Specificities", pages 47-54, see entire document.
 [Y]  - Cancer Research, Vol. 50, issued 01 April 1990, NEUMAIER et al.: "Cloning of the Genes for T84,66, and Antibody... Hampster Ovary Cells", pages 2128-2134, entire document.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.