EP0692029 - GENETICALLY ENGINEERED GLUTAMINASE AND ITS USE IN THERAPY [Right-click to bookmark this link] | |||
Former [1996/03] | GENETICALLY ENGINEERED GLUTAMINASE AND ITS USE IN ANTIVIRAL AND ANTICANCER THERAPY | ||
[2006/44] | Status | No opposition filed within time limit Status updated on 14.03.2008 Database last updated on 31.08.2024 | Most recent event Tooltip | 18.04.2008 | Lapse of the patent in a contracting state New state(s): GR | published on 21.05.2008 [2008/21] | Applicant(s) | For all designated states ME MEDICAL ENZYMES AG Frohburgweg 7 CH-6340 Baar / CH | [2007/19] |
Former [1996/03] | For all designated states ME MEDICAL ENZYMES AG Frohburgweg 7 CH-6340 Baar / CH | Inventor(s) | 01 /
ROBERTS, Joseph 6 Sunturf Circle Columbia, SC 29223 / US | 02 /
MacALLISTER, Thomas W. 308 E. Meadow Court Columbia, SC 29210 / US | 03 /
SETHURAMAN, Natarajan 1340 Long Creek Drive 713 Columbia, SC 29210 / US | 04 /
FREEMAN, Abbie G. 1538 Lonsford Road Columbia, SC 29206 / US | [1996/03] | Representative(s) | Wright, Simon Mark, et al J A Kemp 14 South Square Gray's Inn London WC1R 5JJ / GB | [N/P] |
Former [2001/21] | Wright, Simon Mark, et al J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5LX / GB | ||
Former [2001/03] | Tombling, Adrian George, et al Withers & Rogers Goldings House 2 Hays Lane London SE1 2HW / GB | ||
Former [1996/03] | Dean, John Paul, et al Withers & Rogers 4 Dyer's Buildings Holborn London EC1N 2JT / GB | Application number, filing date | 93900818.1 | 04.12.1992 | [1996/03] | WO1992US10421 | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9413817 | Date: | 23.06.1994 | Language: | EN | [1994/14] | Type: | A1 Application with search report | No.: | EP0692029 | Date: | 17.01.1996 | Language: | EN | The application published by WIPO in one of the EPO official languages on 23.06.1994 takes the place of the publication of the European patent application. | [1996/03] | Type: | B1 Patent specification | No.: | EP0692029 | Date: | 09.05.2007 | Language: | EN | [2007/19] | Search report(s) | International search report - published on: | EP | 23.06.1994 | Classification | IPC: | C12N15/55, C12N9/80, A61K47/48, A61K48/00, C12N1/21 | [2006/44] | CPC: |
C12N9/82 (EP,US);
A61K47/6815 (EP,US);
A61K47/6865 (EP,US);
A61K47/6899 (EP,US);
A61P31/12 (EP);
A61P35/00 (EP);
B82Y5/00 (EP,US);
C07K16/3053 (EP,US);
C07K19/00 (EP,US);
C12N9/80 (EP,US);
C12Y305/01038 (EP,US);
A61K38/00 (EP,US);
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Former IPC [1996/03] | C12N15/55, A61K37/54, C12N9/80, C07K13/00, A61K47/48, A61K48/00, A61K9/127, C12N1/21 | Designated contracting states | AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1996/03] | Title | German: | GENTECHNOLOGISCH HERGESTELLTE GLUTAMINASE UND IHRE VERWENDUNG IN THERAPIE | [2006/44] | English: | GENETICALLY ENGINEERED GLUTAMINASE AND ITS USE IN THERAPY | [2006/44] | French: | GLUTAMINASE PRODUITE PAR GÉNIE GÉNETIQUE ET SON UTILISATION EN THÉRAPIE | [2006/44] |
Former [1996/03] | GENETECHNOLOGISCH HERGESTELLTE GLUTAMINASE UND IHRE VERWENDUNG IN ANTIVIRALER UND ANTIKREBSTHERAPIE | ||
Former [1996/03] | GENETICALLY ENGINEERED GLUTAMINASE AND ITS USE IN ANTIVIRAL AND ANTICANCER THERAPY | ||
Former [1996/03] | GLUTAMINASE PRODUITE PAR GENIE GENETIQUE ET SON UTILISATION EN THERAPIE ANTIVIRALE ET ANTICANCEREUSE | Biological material | This application mentions deposited biological material, check the file for details | Entry into regional phase | 28.04.1995 | National basic fee paid | 28.04.1995 | Designation fee(s) paid | 28.04.1995 | Examination fee paid | Examination procedure | 09.06.1994 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 28.04.1995 | Examination requested [1996/03] | 26.04.1996 | Despatch of a communication from the examining division (Time limit: M06) | 05.12.1996 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 11.02.1997 | Reply to a communication from the examining division | 04.06.1998 | Despatch of a communication from the examining division (Time limit: M06) | 14.12.1998 | Reply to a communication from the examining division | 10.11.1999 | Despatch of a communication from the examining division (Time limit: M06) | 18.05.2000 | Reply to a communication from the examining division | 08.02.2001 | Despatch of a communication from the examining division (Time limit: M08) | 16.10.2001 | Reply to a communication from the examining division | 19.02.2002 | Despatch of a communication from the examining division (Time limit: M06) | 23.08.2002 | Reply to a communication from the examining division | 04.02.2004 | Despatch of a communication from the examining division (Time limit: M07) | 14.09.2004 | Reply to a communication from the examining division | 17.11.2006 | Communication of intention to grant the patent | 15.03.2007 | Fee for grant paid | 15.03.2007 | Fee for publishing/printing paid | Divisional application(s) | EP07009229.1 / EP1854876 | Opposition(s) | 12.02.2008 | No opposition filed within time limit [2008/16] | Request for further processing for: | 11.02.1997 | Request for further processing filed | 11.02.1997 | Full payment received (date of receipt of payment) Request granted | 25.02.1997 | Decision despatched | Fees paid | Renewal fee | 27.05.1995 | Renewal fee patent year 03 | 07.12.1995 | Renewal fee patent year 04 | 09.12.1996 | Renewal fee patent year 05 | 05.12.1997 | Renewal fee patent year 06 | 21.12.1998 | Renewal fee patent year 07 | 06.12.1999 | Renewal fee patent year 08 | 07.12.2000 | Renewal fee patent year 09 | 07.12.2001 | Renewal fee patent year 10 | 28.11.2002 | Renewal fee patent year 11 | 18.12.2003 | Renewal fee patent year 12 | 07.12.2004 | Renewal fee patent year 13 | 13.12.2005 | Renewal fee patent year 14 | 12.12.2006 | Renewal fee patent year 15 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | DK | 09.05.2007 | GR | 10.08.2007 | PT | 09.10.2007 | [2008/21] |
Former [2008/12] | DK | 09.05.2007 | |
PT | 09.10.2007 | ||
Former [2008/08] | DK | 09.05.2007 | Cited in | International search | [Y]CA1168150 (UNIV ALBERTA [CA]); | [Y]US4762707 (JANSEN FRANZ [FR], et al) | [A] - Roberts, et al., "Inhibition of mouse retroviral disease by bioactive glutaminase-asparaginase", J. Gen. Virol., 72:299-305 (1991). | [AO] - Ollenschl{ger, et al., "Intestinal Glutamine Metabolism of Patients with HIV-Infection", Clinical Nutrition, 9:48-49 (1990). | [AO] - Roberts, et al., "Glutaminase has potent antiretroviral activity in vivo", Abstract, Proc. Am. Assoc. Cancer Res., 30:454 (1989). | [Y] - Schmer, et al., "Kinetics of Uptake and Activity in Mouse Liver of Glutaminase Coupled to Desialated Orosomucoid", Biochimica et Biophysica Acta, 538:397-405 (1978). | [A] - Shapiro, et al., "Isolation, Characterization, and in Vitro Expression of a cDNA That Encodes the Kidney Isoenzyme of the Mitochondrial Glutaminase", J. Biol. Chem., 266:18792-18796 (1991). | [X] - Roberts, et al., "Biologic and Antineoplastic Effects of Enzyme-Mediated In Vivo Depletion of L-Glutamine, L-Tryptophan, and L-Histidine", Cancer Treatment Reports, 63:1045-1054 (1979). | [A] - Wu, et al., "Receptor-mediated Gene Delivery in Vivo", J. Biol. Chem., 266:14338-14342 (1991). | [A] - Nicolau, et al., "Liposomes as Carriers for in Vivo Gene Transfer and Expression", Meth. Enzymol., 149:157-176 (1987). | Examination | - J. GEN. VIROL. vol. 72, no. 2, February 1991, COLCHESTER, UK pages 299 - 305 J. ROBERTS & W.G. MCGREGOR 'Inhibition of mouse retroviral disease by bioactive glutaminase-asparaginase' cited in the application | - CLIN. NUTR. (EDINB.) vol. 9, no. 1, February 1990, EDINBURGH, UK pages 48 - 49 G. OLLENSCHL[GER ET AL. 'Intestinal Glutamine Metabolism of Patients with HIV-Infection' | - PROC. AM. ASSOC. CANCER RES. ANNU. MEET.; ABSTR.NO. 1806 vol. 30, no. 0, 1989, page 454 J. ROBERTS & W.G. MCGREGOR 'Glutaminase has potent entiretroviral activity in vivo' | - BIOCHIMICA ET BIOPHYSICA ACTA vol. 538, 1978, AMSTERDAM, NL pages 397 - 405 G. SCHMER ET AL. 'KINETICS OF UPTAKE AND ACTIVITY IN MOUSE LIVER OF GLUTAMINASE COUPLED TO DESIALATED OROSOMUCOID' | - JOURNAL OF BIOLOGICAL CHEMISTRY. (MICROFILMS) vol. 266, no. 28, 5 October 1991, BALTIMORE, MD US pages 18792 - 18796 R.A. SHAPIRO ET AL. 'Isolation, Characterization, and in Vitro Expression of a cDNA That Encodes the Kidney Isoenzyme of the Mitochondrial Glutaminase' | - CANCER TREATMENT REPORTS vol. 63, no. 6, June 1979, BETHESDA, MD, USA pages 1045 - 1054 J. ROBERTS ET AL. 'Biologic and Antineoplastic Effects of Enzyme-Mediated In Vivo Depletion of L-Glutamine, L-Tryptophan, and L-histidine' cited in the application | - JOURNAL OF BIOLOGICAL CHEMISTRY. (MICROFILMS) vol. 266, no. 22, 5 August 1991, BALTIMORE, MD US pages 14338 - 14342 G.Y. WU ET AL. 'Receptor-mediated Gene Delivery in Vivo' cited in the application | - METHODS IN ENZYMOLOGY, VOL. 149, PART B 1987, NEW YORK, US pages 157 - 176 C. NICOLAU ET AL. 'Liposomes as Carriers for in Vivo Gene Transfer and Expression' cited in the application |